Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit

A technology for gastrointestinal diseases and compositions, which is applied in the directions of medical preparations containing active ingredients, drug combinations, plant/algae/fungus/moss components, etc., can solve the problems of aggravating gastric ulcer or duodenal ulcer and large side effects. , to achieve the effect of improving gastrointestinal diseases

Inactive Publication Date: 2016-02-24
HURUM +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to alleviate the above symptoms, quick-acting antacids are taken, but they can only work temporarily, and steroidal and non-steroidal anti-inflammatory analgesics are restricted due to their side effects
In particular, non-steroidal anti-inflammatory analgesics such as aspirin and ibuprofen can aggravate gastric or duodenal ulcers. Therefore, patients with ulcers are prohibited from taking them or taking them together with antacids is subject to many restrictions.

Method used

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  • Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit
  • Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit
  • Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment one : Essential oil component of pure fruit of Litsea japonica

[0046] Add 5000ml of 95% ethanol to 500g of freeze-dried pure fruit of Litsea japonica, stir and extract at room temperature 20°C for 24 hours, remove alcohol, and add water step by step to obtain 85g of pure fruit of Litsea japonica essential oil components.

Embodiment 2

[0047] Embodiment two : Essential oil component of Litsea japonica pure fruit

[0048] After adding 5000 ml of n-hexane to 500 g of freeze-dried pure fruit of Litsea Cubeja, stirring and extracting at room temperature for 24 hours at 20° C., the hexane was removed to obtain the essential oil components of 95 g of pure fruit of Litsea Cube.

Embodiment 3

[0049] Embodiment three : Seed essential oil component of Litsea japonica fruit

[0050] After adding 5000 ml of n-hexane to 500 g of freeze-dried Litsea japonica seeds, stirring and extracting at room temperature for 24 hours at 20° C., the hexane was removed to obtain 46 g of the essential oil components of the pure fruit of Litsea cubeba japonica.

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Abstract

The present invention relates to a composition for preventing and treating gastrointestinal diseases by using Litsea japonica, and specifically, to a composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from Litsea japonica fruit as an active ingredient. According to the present invention, the essential oils extracted from Litsea japonica fruits (pure fruit, seed fruit, and seeds) and used as the active ingredient of the composition for preventing and treating gastrointestinal diseases have been confirmed to have excellent effects in an efficacy evaluation for relieving gastrointestinal diseases caused by Helicobacter pylori, which is a gastrointestinal disease factor, physical factors induced by stress, and chemical factors induced by indomethacin. Therefore, the essential oils extracted from Litsea japonica fruit (pure fruit, seed fruit, and seeds) are useful for preventing and treating gastrointestinal diseases caused by various factors.

Description

technical field [0001] The invention relates to a composition for preventing and treating gastrointestinal diseases by using japonica japonica, in more detail, to a composition for preventing and treating gastrointestinal diseases using essential oil components obtained from the fruit of japonica japonica as an effective ingredient. Background technique [0002] In 1999, the number of diagnosed and treated patients with digestive system diseases in Korea reached 599 out of 100,000, second only to 1,156 patients with respiratory system diseases (Ministry of Health and Welfare, 2001). Among 100,000 people, the death rate is 30.1, which accounts for a very high rate (Statistical Bureau, 2002). [0003] Digestive system diseases are increasing due to bacterial factors, stress factors, ethanol and other drug factors, dietary life factors, aging and other factors. [0004] The factors that cause gastrointestinal diseases can be roughly divided into bacterial disease factors such ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P1/04
CPCA61K36/54A61P1/04
Inventor 曹柱铉朴仁在郑龙焕崔九熙尹源钟朴成桓尹支铉白顺玉
Owner HURUM
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