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Medicine composition for treating functional constipation and preparation method of medicine composition

A technology of functional constipation and composition, which is applied in the field of pharmaceutical composition for treating functional constipation and its preparation, and can solve problems such as colonic melanosis, many adverse reactions, and laxative-addicted "constipation"

Inactive Publication Date: 2016-02-24
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of functional constipation is still mainly based on conservative medical treatment. The commonly used drugs for treating constipation are mainly stimulant laxatives, which have many adverse reactions. "laxative-addicted" constipation, and various drugs for treating constipation can only play a short-term therapeutic effect, once the drug is stopped, the constipation will recur immediately

Method used

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  • Medicine composition for treating functional constipation and preparation method of medicine composition
  • Medicine composition for treating functional constipation and preparation method of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: The pharmaceutical composition for the treatment of functional constipation and its preparation method

[0032] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating functional constipation are: papiliochrome II 23g cassia japonica 385g chrysanthemum chrysanthemum 385g sangshin D 5.4g renthrin B 54.3g mikanolide 14g;

[0033] Preparation method: according to the ratio of the raw materials, take cayenne plum, chrysanthemum chrysanthemum, papiliochrome II, sangsin D, astragalin B, and mikanolide, mix them evenly, and use ethanol with a concentration of 37% by weight as the preparation method. Solvent, soaking and extracting at 30°C, the number of extractions is 13 times, and the extraction time is 13 hours each time, and the amount of solvent used each time is 17 times the total weight of the raw material drug, and filtered to obtain the dregs A and the extract, and the extract is recovered Ethanol, concentrated...

Embodiment 2

[0034] Embodiment 2: the pharmaceutical composition for the treatment of functional constipation and its preparation method

[0035] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating functional constipation are: papiliochrome II 22g cassia japonica 395g chrysanthemum chrysanthemum 375g sangshinin D 5.8g astragalusin B54g mikanolide 16g;

[0036] Preparation method: according to the ratio of the raw materials, take cayenne plum, chrysanthemum chrysanthemum, papiliochrome II, sangsin D, astragalin B, and mikanolide, mix them evenly, and use ethanol with a concentration of 37% by weight as the preparation method. Solvent, soaking and extracting at 30°C, the number of extractions is 13 times, and the extraction time is 13 hours each time, and the amount of solvent used each time is 17 times the total weight of the raw material drug, and filtered to obtain the dregs A and the extract, and the extract is recovered Ethanol, concentr...

Embodiment 3

[0037] Embodiment 3: the pharmaceutical composition for the treatment of functional constipation and its preparation method

[0038] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating functional constipation are: papiliochrome II 24g cassia japonica 375g chrysanthemum chrysanthemum 395g sangshin D 45g astragalin B 4.6g mikanolide 12g;

[0039] Preparation method: according to the ratio of the raw materials, take cayenne plum, chrysanthemum chrysanthemum, papiliochrome II, sangsin D, astragalin B, and mikanolide, mix them evenly, and use ethanol with a concentration of 37% by weight as the preparation method. Solvent, soaking and extracting at 30°C, the number of extractions is 13 times, and the extraction time is 13 hours each time, and the amount of solvent used each time is 17 times the total weight of the raw material drug, and filtered to obtain the dregs A and the extract, and the extract is recovered Ethanol, concentrated...

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Abstract

The invention discloses a medicine composition for treating functional constipation and a preparation method of the medicine composition. The medicine composition is prepared from the following active pharmaceutical ingredients according to a certain ratio: papiliochrome II, anemone rivularis, saussurea brunneopilosa Hand.-Mazz., morusin D, fastigilin B and mikanolide. The medicine composition can be prepared into various preparation formulations according to conventional preparation processes, and has a remarkable treating effect on functional constipation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating functional constipation and a preparation method thereof. Background technique [0002] Functional constipation (Functional constipation, FC) refers to the intestinal functional disease with reduced frequency of defecation, accompanied by difficulty or incomplete defecation, and dry stool. It is a common and frequently-occurring disease in clinical practice. The pathogenesis of functional constipation is very complex, and its pathophysiological mechanism is not yet clear. According to the results of epidemiological investigations and related research, functional constipation is related to factors such as lifestyle, eating habits, gender, age, and autonomic dysfunction. As our country enters the aging stage, the incidence of functional constipation in the elderly is increasing year by year, and the symptom...

Claims

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Application Information

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IPC IPC(8): A61K36/80A61K36/71A61P1/10A61K31/365A61K31/352A61K31/198
CPCA61K36/80A61K9/2031A61K9/2059A61K9/4866A61K31/198A61K31/352A61K31/365A61K36/285A61K36/71A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 邵培财
Owner JINAN XINGYI MEDICAL TECH
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