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Root paint relieving tablet and preparation method thereof

A technology of kudzu root and blocking collaterals, applied in the field of Gentongping tablet and its preparation, can solve the problems of slow disintegration, unsatisfactory curative effect, low curative effect and the like

Inactive Publication Date: 2016-02-24
HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the composition and process of Gentongping Tablets on the market, the curative effect is not ideal. The preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect.

Method used

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  • Root paint relieving tablet and preparation method thereof
  • Root paint relieving tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Take 75.2g of schisandra, 18.8g of polygala, 188g of Andrographis paniculata, 47g of kudzu root, 50g of peach kernel, 56.4g of safflower, 47g of frankincense, 50g of myrrh, 150.4g of Dipsacus, 75g of dog spine (hot), 75.2g of Shenjincao, and grind them into 60-mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 19Mpa, extraction temperature 16°C, separator pressure 12Mpa, separator temperature 36°C, separation time 1.9 hours, carbon dioxide flow rate 25L per hour, to obtain the extract; The solution was dried under reduced pressure at 62°C to obtain a dry cream; take the dry cream and add 80 g of citric acid, and use a high-energy nano-impact mill to pulverize it into a mixed dry cream powder with a particle size of 200-300 nm; take the mixed dry cream powder, 35 g of microcrystalline cellulose, Hypromellose 35g, croscarmellose sodium 35g, magnesium aluminum silicate 15g, sodium chloride 5g, mannitol 4g, maltodextrin 4g, mix well...

specific Embodiment 2

[0035] Take 75.2g of schisandra, 18.8g of polygala, 188g of Andrographis paniculata, 47g of kudzu root, 50g of peach kernel, 56.4g of safflower, 47g of frankincense, 50g of myrrh, 150.4g of Dipsacus, 75g of dog spine (hot), 75.2g of Shenjincao, and grind them into 60 mesh coarse powder, extracted by supercritical carbon dioxide extraction, extraction pressure 39Mpa, extraction temperature 44°C, separator pressure 19Mpa, separator temperature 60°C, separation time 3.5 hours, carbon dioxide flow rate 33L per hour, to obtain the extract; The solution was dried under reduced pressure at 80°C to obtain a dry cream; take the dry cream and add 120g of citric acid, and use a high-energy nano-impact mill to pulverize it into a mixed dry cream powder with a particle size of 200-300nm; take the mixed dry cream powder, 45g of microcrystalline cellulose, Hypromellose 45g, croscarmellose sodium 45g, magnesium aluminum silicate 25g, sodium chloride 15g, mannitol 6g, maltodextrin 6g, mix well,...

Embodiment 3

[0037] Take 75.2g of schisandra, 18.8g of polygala, 188g of Andrographis paniculata, 47g of kudzu root, 50g of peach kernel, 56.4g of safflower, 47g of frankincense, 50g of myrrh, 150.4g of Dipsacus, 75g of dog spine (hot), 75.2g of Shenjincao, and grind them into 60 mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 29Mpa, extraction temperature 30°C, separator pressure 16Mpa, separator temperature 48°C, separation time 2.7 hours, carbon dioxide flow rate 29L per hour, to obtain the extract; The solution was dried under reduced pressure at 71°C to obtain a dry cream; take the dry cream and add 100 g of citric acid, and use a high-energy nano-impact mill to pulverize it into a mixed dry cream powder with a particle size of 200-300 nm; take the mixed dry cream powder, 40 g of microcrystalline cellulose, Hypromellose 40g, croscarmellose sodium 40g, magnesium aluminum silicate 20g, sodium chloride 10g, mannitol 5g, maltodextrin 5g, mix we...

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Abstract

The invention discloses a root paint relieving tablet and a preparation method thereof. The root paint relieving tablet is characterized in that 75.2 g of schisandra chinensis, 18.8 g of polygala tenuifolia, 188 g of common andrographis herb, 47 g of radix puerariae, 50 g of peach kernels, 56.4 g of flos carthami, 47 g of frankincense, 50 g of myrrh, 150.4 g of dipsacus asperoids, 75 g of burned woodwardia japonica and 75.2 g of lycopodium clavatum are extracted through the carbon dioxide supercritical extraction method and are then depressurized and dried, materials are then ground into nanometer dry paste through high-energy nanometer impact grinding, functional auxiliary materials are added, the root paint relieving tablet is prepared, the disintegration time is remarkably shortened, the curative effect is remarkably better than that of root paint relieving tablets sold in the market, and the positive effect is achieved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a Gentongping tablet and a preparation method thereof. Background technique [0002] Gentongping Tablets promote blood circulation, dredge collaterals, and relieve pain. For cervical spondylosis caused by wind-cold blocking collaterals, symptoms include shoulder and neck pain, limited mobility, and numbness of upper limbs. The commercially available Gentongping Tablets have unsatisfactory curative effect due to the composition and process, and the preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect. Contents of the invention [0003] In order to overcome the above disadvantages, the present invention provides a Gentongping Tablet with fast disintegration speed and high curative effect and a preparation method thereof. [0004] Invention embodiment is as follows: [0005] Take 75.2g of schis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K9/20A61K47/38A61P19/00
CPCA61K36/79A61K9/2009A61K9/2013A61K9/205A61K9/2054A61K9/2059A61K36/11A61K36/185A61K36/19A61K36/286A61K36/324A61K36/328A61K36/488A61K36/57A61K36/69A61K36/736A61K2236/37A61K2236/51
Inventor 不公告发明人
Owner HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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