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Hemostatic gel for surgery

A hemostatic gel and technology for surgery, applied in the field of hemostatic gel for surgery and its preparation method, can solve the problems of high secondary infection rate, large foreign body reaction in tissues, etc., achieve convenient use, relieve pain, and prevent postoperative adhesion Effect

Inactive Publication Date: 2016-02-03
邢月军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Absorbable gelatin sponge is currently the most commonly used hemostatic material in clinical practice, but the clinical use of absorbable gelatin sponge has the disadvantages of high secondary infection rate and large tissue foreign body reaction.

Method used

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  • Hemostatic gel for surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 A hemostatic gel for surgery, prepared from the following main raw materials in parts by weight (160 g per part): 42 parts of chitosan, 28 parts of carbomer, 7 parts of gardenia, 10 parts of forsythia , 6 parts of winter melon skin, 9 parts of Panax notoginseng, 4 parts of lotus root, 11 parts of pinellia, 8 parts of Fangfeng, 7 parts of Akebia, 8 parts of notopterygium, 5 parts of Viola chinensis, 10 parts of honeysuckle, appropriate amount of moisturizing agent, antioxidant The right amount of preservatives and the right amount of preservatives.

[0042] The preparation method of above-mentioned operation hemostatic gel is:

[0043] (1) Mix gardenia and forsythia, add water to decoct twice, the amount of water added is 4.6 times the total weight of the two kinds of Chinese herbal medicines, decoct for 1.2 hours each time, combine the decoction, filter with a microporous membrane, The filtrate is concentrated into a medicinal solution with a relative density...

Embodiment 2

[0049] Example 2 A hemostatic gel for surgery, prepared from the following main raw materials in parts by weight (each part is 160 g): 56 parts of chitosan, 40 parts of carbomer, 16 parts of gardenia, 14 parts of forsythia , 11 parts of wax gourd skin, 16 parts of Panax notoginseng, 8 parts of lotus root, 16 parts of pinellia, 13 parts of Fangfeng, 15 parts of Akebia, 15 parts of notopterygium, 10 parts of Viola chinensis, 14 parts of honeysuckle, appropriate amount of moisturizing agent, anti-oxidant The right amount of preservatives and the right amount of preservatives.

[0050] The preparation method of above-mentioned operation hemostatic gel is:

[0051] (1) Mix gardenia and forsythia, add water to decoct twice, the amount of water added is 6.5 times the total weight of the two kinds of Chinese herbal medicines, decoct for 1.2 hours each time, combine the decoction, filter with a microporous membrane, The filtrate is concentrated into a medicinal solution with a relativ...

Embodiment 3

[0057] Example 3 A hemostatic gel for surgery, prepared from the following main raw materials in parts by weight (each part is 160 g): 45 parts of chitosan, 30 parts of carbomer, 10 parts of gardenia, 11 parts of forsythia , 7 parts of wax gourd skin, 11 parts of Panax notoginseng, 5 parts of lotus root, 13 parts of Pinellia, 9 parts of Fangfeng, 9 parts of Akebia, 10 parts of notopterygium, 7 parts of Viola chinensis, 11 parts of honeysuckle, appropriate amount of moisturizing agent, anti-oxidant The right amount of preservatives and the right amount of preservatives.

[0058] The preparation method of above-mentioned operation hemostatic gel is:

[0059] (1) Mix gardenia and forsythia, add water to decoct twice, the amount of water added is 4.8 times the total weight of the two Chinese herbal medicines, decoct for 1.2 hours each time, combine the decoction, filter with a microporous membrane, The filtrate is concentrated into a medicinal solution with a relative density of ...

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Abstract

The invention discloses a hemostatic gel for surgery and a preparation method thereof. The hemostatic gel is prepared from the following main raw materials by weight: 42 to 56 of chitosan, 28 to 40 of carbomer, 7 to 16 of cape jasmine, 10 to 14 of fructus forsythia, 6 to 11 of white gourd peel, 9 to 16 of pseudo-ginseng, 4 to 8 of lotus rhizome node, 11 to 16 of pinellia ternate, 8 to 13 of divaricate saposhnikovia root, 7 to 15 of akebia stem, 8 to 15 of notopterygium root, 5 to 10 of Yedo violet, 10 to 14 of honeysuckle flower, a proper amount of a humectant, a proper amount of an anti-oxidant and a proper amount of an antiseptic. The prepared hemostatic gel is convenient to use and free of toxicity and harm to the human body, has good biocompatibility and reliable security, can be biologically degraded and absorbed, is capable of stopping bleeding, relieving pain, eliminating swelling, inhibiting bacteria and eliminating inflammation, is fast in stopping bleeding, can shorten surgery time, prevents occurrence of adverse adhesion, decreases postoperative infective rate and morbidity, effectively mitigates pain of patients, accelerates wound healing, promotes postoperative rehabilitation and reduces hospitalization expenses.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to a hemostatic gel for operation and a preparation method thereof. Background technique [0002] Hemostasis plays an important role in reducing blood loss during operation, keeping the operative field clear, preventing important tissue damage, ensuring surgical safety, and postoperative wound healing. The commonly used methods of hemostasis in surgery include the following: (1) clamping and ligation to stop bleeding. That is, the visible bleeding point is quickly and accurately clamped to stop bleeding with a vascular clamp. Do not pinch blindly. If the bleeding point cannot be seen clearly due to bleeding, you can use gauze to compress it, and then pinch it after seeing it clearly. The tissue to be clamped should be less, so as not to damage the normal tissue around the blood vessel too much. For superficial small blood vessels, simple clamping can achieve...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61K9/06A61P17/02A61P7/04A61P29/00A61P31/02A61P41/00A61L24/08A61L24/06
Inventor 不公告发明人
Owner 邢月军
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