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A compound biological preparation for the treatment of encephalopathy

A biological preparation, encephalopathy technology, applied in the field of medicine, can solve problems such as large side effects, poor curative effect, inability to cure, and achieve the effect of reducing blood and intestinal toxins

Active Publication Date: 2018-06-01
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing drugs for the treatment of brain or nerve damage diseases still have defects such as large side effects, poor curative effect, and inability to cure

Method used

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  • A compound biological preparation for the treatment of encephalopathy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1) Medicinal raw materials: 1 part of Rosa roxburghii root, 2 parts of June Snow, 5 parts of Periwinkle, 2 parts of Blood Pendant Grass, 4 parts of Yin Xingcao, 5 parts of Hair Holly, 2 parts of Asarum, 8 parts of Campotropia, Shan Ci 7 parts of mushrooms, 8 parts of colchicum, 2 parts of styrax, 5 parts of acute seed, 7 parts of schisandra, 1 part of scutellaria baicalensis, and 1 part of Yu Liren respectively or after mixing, add 30 times the total weight of pure water at 90-100 ° C for heat preservation extraction, The extraction time is 60 minutes, and then filtered with a vibrating sieve, the filtrate is cooled and left standing for later use, and the filter residue is extracted for the second time; during the second extraction, pure water 8 times the total weight is added, the temperature is 90-100 °C, and the extraction time is After 40 minutes, filter with a vibrating sieve after extraction, combine the two filtrates, wait for the temperature of the filtrate to c...

Embodiment 2

[0033] 1) Medicinal raw materials: 6 parts of Rosa roxburghii root, 9 parts of Liuyuexue, 10 parts of Periwinkle, 8 parts of Blood Pendant Grass, 15 parts of Yin Xingcao, 18 parts of Hair Holly, 5 parts of Asarum, 12 parts of Campotropia, Shan Ci 10 parts of mushrooms, 12 parts of colchicum, 8 parts of styrax, 9 parts of schisandra, 10 parts of schisandra, 5 parts of scutellaria baicalensis, and 5 parts of Yu Liren, respectively or after mixing, add 30 times the total weight of pure water at 90-100 ° C for heat preservation extraction, The extraction time is 60 minutes, and then filtered with a vibrating sieve, the filtrate is cooled and left standing for later use, and the filter residue is extracted for the second time; during the second extraction, pure water 15 times the total weight is added, the temperature is 90-100 ° C, and the extraction time is After 40 minutes, filter with a vibrating sieve after extraction, combine the two filtrates, wait for the temperature of the ...

Embodiment 3

[0037] 1) Medicinal raw materials: 3 parts of Rosa roxburghii root, 4 parts of June Snow, 6 parts of Periwinkle, 4 parts of Blood Pendant Grass, 5 parts of Yin Xingcao, 8 parts of Hair Holly, 3 parts of Asarum, 10 parts of Campotropia, Shan Ci 8 parts of mushrooms, 8 parts of colchicum, 2 parts of styrax, 5 parts of acute seed, 7 parts of schisandra, 3 parts of scutellaria, and 2 parts of Yu Liren respectively or after mixing, add 15 times the total weight of pure water at 90-100 ° C for heat preservation extraction, The extraction time is 30 minutes, and then filtered with a vibrating sieve, the filtrate is cooled and left standing for later use, and the filter residue is extracted for the second time; during the second extraction, pure water 8 times the total weight is added, the temperature is 90-100 °C, and the extraction time is After 20 minutes, filter with a vibrating sieve after extraction, combine the two filtrates, wait for the temperature of the filtrate to cool belo...

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Abstract

The invention relates to a compound biological preparation for treating encephalopathy, which comprises 15-35 parts by weight of dry powder of raw material extract of medicinal materials, 3-10 parts by weight of active peptide and 1-5 parts by weight of leech powder; the dry powder of raw material extract of medicinal materials consists of the following The medicinal material extracts are obtained by spraying and drying in parts by weight: 1-6 parts of Rosa roxburghii root, 2-9 parts of Liuyuexue, 5-10 parts of Periwinkle, 2-8 parts of Spleenia chinensis, 4-15 parts of Yinxingcao, holly holly 5 to 18 parts, 2 to 5 parts of asarum, 8 to 12 parts of magma fruit, 7 to 10 parts of Shanzi mushroom, 8 to 12 parts of colchicum, 2 to 8 parts of styrax, 5 to 9 parts of acute seed, 7 to 7 parts of schisandra 10 parts, 1 to 5 parts of Scutellaria baicalensis, 1 to 5 parts of Yu Liren. The present invention adopts specific traditional Chinese medicine components, active peptides and leech powder to combine with etiology and symptomatic treatment, through the effects of clearing away heat and detoxification, promoting dampness, cooling blood and dispelling blood stasis, stopping bleeding, expelling heat and laxative, so as to achieve anti-cooling blood, Hemostasis, absorption of intestinal and blood endotoxins to protect the liver and brain and prevent encephalopathy.

Description

technical field [0001] The invention relates to a composite biological preparation for treating encephalopathy, which belongs to the field of medicine. Background technique [0002] Hepatic encephalopathy (HE) is a central nervous system dysfunction syndrome based on metabolic disorders caused by severe liver disease. According to clinical manifestations, encephalopathy is divided into four stages. The first stage (prodromal stage) is characterized by mild personality changes and behavioral disturbances, and sometimes the symptoms are not obvious and are easily ignored. The second stage (pre-coma) is mainly characterized by confusion, sleep disturbance, and behavioral disturbance. The third period is the drowsy period, and the fourth period is the coma period. Subclinical encephalopathy is a subclinical state that widely exists in chronic liver diseases. Patients do have mental retardation and decreased responsiveness, but no obvious clinical manifestations and biochemica...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K38/06A61K38/01A61P1/16A61P25/00A61K36/898A61K35/62
Inventor 程率芳杨小红周春蕾
Owner HENAN UNIV OF CHINESE MEDICINE
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