Box type DNA sequencing instrument with frame type shock absorption structure

Abstract

The invention relates to a box type DNA sequencing instrument with a frame type shock absorption structure. The box type DNA sequencing instrument comprises a response record subsystem, a reagent supply system, a control system and a sequencing instrument box body for loading the systems, wherein the sequencing instrument box body comprises a main supporting component for supporting a bottom part, a side part, a back part and a division part between a left box body area and a right box body area of the box body; the main supporting component is formed by splicing steel plates, is fixed by splicing or bolt fastening, and comprises a base component, a top plate component, a supporting frame component which is connected with the base component to form a side frame of the box body, and a buffer system mounting seat; and the supporting frame component comprises a left side vertical plate component and a middle vertical plate component for separating a left box body and a right box body. The box type DNA sequencing instrument with the frame type shock absorption structure has a frame structure composed of the steel plate and has a strong shock absorption effect; sequencing reaction and reagent supply equipment should have a stable and closed operating environment; and the box type DNA sequencing instrument is stable in overall structure and high in sequencing efficiency.

Description

technical field [0001] The invention relates to the field of DNA sequencing, in particular to a box-type DNA sequencer with a frame-type shock-absorbing structure. Background technique [0002] In the field of DNA sequencing technology, pyrosequencing technology (pyrosequencing) is a new enzyme cascade sequencing technology developed by Nyren et al. in 1987. Its repeatability and accuracy are comparable to Sanger method DNA sequencing technology. , while the speed is greatly improved. [0003] The overall operation process is described as follows: After the DNA sample is crushed, the library construction reagent is used to add adapters, single-strand capture, bind to microspheres, microemulsion PCR amplification, and emulsion breaking to obtain a DNA library built on microspheres. The template lays the library and the enzymes required for the sequencing reaction on the sequencing chip with a micro-reaction pool, installs the sequencing chip and sequencing reagents on the ho...

AI Technical Summary

Problems solved by technology

[0004] In the actual DNA sequencing process, the sequencing reaction and reagent supply equipment are required to have a stable and closed operating environment; the existing DNA sequencing equipment is difficult to meet the above requirements

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