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A spray for eliminating liver odor in patients with liver failure and its preparation method

A technology for patients with liver failure, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, antifungal agents, etc., can solve the problem of ineffective reduction of complications in patients with liver failure and the ineffective prevention of oral infection. Short refreshing time and other problems, achieve the effect of improving liver function damage and jaundice, removing bad breath, and reducing oral infection

Inactive Publication Date: 2018-10-30
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Existing medicines for removing bad breath include sprays and mouthwashes for eliminating bad breath, but the effect of removing bad breath caused by liver failure is not good, and the time for keeping the mouth fresh is short, which cannot prevent oral infection, or is harmful to the oral cavity. The effect of preventing oral infection is not obvious, and it cannot effectively reduce the complications of patients with liver failure, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Ratio (unit: g): Scutellaria baicalensis 20, Bezoar 30, Forsythia 30, Honeysuckle 30, Benzoin 20, Patchouli 15, Perrin 30, Gypsum 30, Coptis 20, Gardenia 20, Coix seed 10, Peppermint 15, Artemisia annua 10, turmeric 20, coriander root 30, thistle 30. A total of 360g, based on the total weight of the crude drug, calculate the appropriate amount of purified water (ml) and the amount (ml) of various liquid medicines.

[0051] Preparation:

[0052] (1) add above-mentioned crude drug to 1500ml pure water and soak for 3 hours, then heat and distill for 3 hours, the distillate is 130ml, and the distillate is obtained for subsequent use; during distillation, the decoction is filtered to obtain the decoction and medicinal residues respectively, for subsequent use;

[0053] (2) add 800ml of pure water to the dregs, heat and cook for 45 minutes, filter to obtain the secondary cooking liquid for later use; combine the two cooking liquids, then heat and concentrate to 250ml, and ob...

Embodiment 2

[0057] Ratio (unit: g): Scutellaria 22, Bezoar 30, Forsythia 28, Honeysuckle 28, Benzoin 18, Patchouli 12, Perrin 32, Gypsum 32, Coptis 18, Gardenia 22, Coix Seed 8, Mint 18, Artemisia annua 8, Curcuma 22, Imperata 28, Thistle 28. A total of 354g.

[0058] Preparation:

[0059] (1) Add the above-mentioned crude drug to 1200ml of pure water and soak for 3.5 hours, then heat and distill for 4 hours, the distillate is 135ml, and the distillate is obtained for subsequent use; during distillation, the boiled liquid is filtered to obtain the cooking liquid and medicinal residues respectively for subsequent use;

[0060] (2) Add 750ml of pure water to the dregs, heat and cook for 40 minutes, filter to obtain the secondary cooking liquid for later use; combine the two cooking liquids, then heat and concentrate to 230ml, and obtain the concentrated liquid for later use;

[0061] (3) Combine the concentrated solution of step (2) and the distilled solution of step (1), then add purifie...

Embodiment 3

[0064] Ratio (unit: g): Scutellaria 18, Bezoar 32, Forsythia 28, Honeysuckle 32, Benzoin 18, Huoxiang 18, Perrin 28, Gypsum 32, Coptis 18, Gardenia 22, Coix seed 10, Mint 15, Artemisia annua 8, Curcuma 18, Imperata 28, Thistle 32. A total of 357g.

[0065] Preparation:

[0066] (1) add above-mentioned crude drug to 1300ml pure water and soak for 3.5 hours, then heat and distill for 4.5 hours, the distillate is 140ml, and the distillate is obtained for subsequent use; during distillation, the boiled liquid is filtered to obtain the cooking liquid and medicinal residues respectively for subsequent use;

[0067] (2) add 800ml of pure water to the dregs, heat and cook for 45 minutes, filter to obtain the secondary cooking liquid for later use; combine the two cooking liquids, then heat and concentrate to 250ml, and obtain the concentrated liquid for later use;

[0068] (3) Combine the concentrated solution of step (2) and the distilled solution of step (1), then add purified wat...

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Abstract

The invention discloses a spraying agent for removing liver stink of hepatic-failure patients and a preparation method. The spraying agent is prepared from the following bulk drugs: radix scutellariae, calculus bovis, forsythia suspensa, flos lonicerae, benzoinum, cablin potchouli herb, herba eupatorii, gypsum fibrosum, rhizoma coptidis, fructus gardeniae, semen coicis, mentha haplocalyx Briq., herba artemisiae annuae, radix curcumae, rhizoma imperatae and common cephalanoplos herb. After being applied for local treatment, the spraying agent is capable of removing oral cavity peculiar smell of a hepatic-failure patient and keeping oral cavity refreshing for a relatively long time, and helps to effectively inhibit oral-cavity bacteria and fungi propagation of the patient and reduce oral cavity infection. The traditional Chinese medicine spraying agent is low in price, and simple and practicable in operation. The spraying agent can be regularly applied to clean oral cavity and maintain oral cavity normal flora. The spraying liquid volume is less and constant at every time, mistaken aspiration is prevented, and the patient safety is guaranteed.

Description

technical field [0001] The invention specifically relates to a spray for eliminating liver odor (odor in the mouth) of patients with liver failure and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] Liver failure is a liver disease syndrome that occurs on the basis of chronic hepatitis B virus carrier, chronic hepatitis or liver cirrhosis. It is the most serious type of various liver diseases, often combined with bacterial and fungal infections, with many complications, difficult treatment, and high mortality. high. Such patients are often accompanied by low immune function, which can easily cause the microecological imbalance of the body, especially after combined bacterial infection, antibiotic use and invasive operation, fungi have gradually become an important factor for secondary infection. The superficial oral cavity was the main site of infection, and the main fungal species were Candida a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K9/12A61P1/02A61P31/04A61P31/10A61K35/413A61K33/06
Inventor 张欣刘华琳王爱武李艳冬
Owner SHANDONG PROVINCIAL HOSPITAL
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