Quickly disintegrated calcium vitamin D tablet and preparation method thereof

Abstract

The invention discloses a quickly-disintegrated calcium vitamin D tablet and a preparation method thereof. The tablet is prepared from the following raw materials in parts by weight: 80-90 parts of calcium acetate, 0.1-1 part of vitamin D3, 2-9 parts of a disintegrating agent, 2-10 parts of filler, 1-8 parts of a lubricating agent and 0.2-2 parts of a flavoring agent. The preparation method comprises the following steps: weighing calcium acetate, vitamin D3, filler and partial lubricating agent, adding into a tablet machine or a rolling machine, and performing primary tabletting to prepare a flake; crushing and grinding the flake into particles having a proper size, adding the disintegrating agent, the flavoring agent and the rest lubricating agent, stirring, mixing and granulating; and sufficiently mixing various raw materials, detecting content and tabletting. According to the calcium vitamin D tablet, the main drug is calcium acetate which is easily hydrolyzed and absorbed, the effective drug has high content, and the tablet can be quickly disintegrated, so that the bioavailability of the medicine can be improved.

Description

technical field [0001] The invention relates to a rapidly disintegrating calcium-vitamin D tablet and a preparation method thereof. The product contains calcium acetate and vitamin D3 and belongs to the field of medicine and health care products. Background technique [0002] Calcium is the most abundant inorganic salt in the human body, accounting for about 2% of the body weight. 99% of the calcium in the human body is distributed in the bones and teeth, the long-term calcium deficiency of the human body first affects the bones. Calcium deficiency in children affects growth and development, and teething is delayed in children. Calcium deficiency in teenagers can cause vertebral deformation, curvature of the spine, and easy loosening of teeth. Due to the decline in the functions of various parts of the body of middle-aged and elderly people, the absorption of calcium is not good, and more serious symptoms will occur, such as osteoporosis, bone hyperplasia, fractures, and i...

AI Technical Summary

Problems solved by technology

Now due to environmental problems, too much exposure to ultraviolet light can cause skin cancer, and it is difficult to meet the needs of the human body simply from food intake, so it is necessary to supplement a certain amount of vitamin D3 products

[0006] Calcium products currently on the market not only contain less calcium and are not easily absorbed by the human body, but also take a long time to disintegrate, which affects the efficacy of the drug

Images