Drug for treating piglet diarrhea, as well as preparation method, detection method and application thereof

Abstract

The invention relates to the field of traditional Chinese medicines, particularly to a drug for treating piglet diarrhea, as well as a preparation method, a detection method and the application thereof. The drug is prepared from the following raw materials in parts by weight: 1-2 parts of sabina chinensis (L.) Ant.[Juiperus chinensis.L.] and 1-2 parts of caryopteris incana (Thunb.) Miq. [Nepeta incana Thunb. ex Houtt.]. The drug can be prepared into powders and granules. The preparation method comprises the following steps: soaking dry sabina chinensis (L.) Ant.[Juiperus chinensis.L.] and dried caryopteris incana (Thunb.) Miq. [Nepeta incana Thunb. ex Houtt.] with 11 times of water for 1 hour for the first time, decocting for 1 hour, decocting for 1 hour with 4 times of water for the second time, merging water decoctions, filtering, concentrating filtrate, drying, grinding into fine powders, screening, uniformly mixing, and preparing into powders. The chromatographic conditions in a drug quality detection method are that a HypersilDs chromatographic column is adopted; acetonitrile and a 0.05 mol / L sodium dihydrogen phosphate solution are adopted as moving phases, and the ratio of acetonitrile to the sodium dihydrogen phosphate solution is 30:70; the detection wavelength is 200 nm; the column temperature is 20 DEG C; the flow rate is 1.0 mL.min<-1>; and the sample amount is 10 [mu]L.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to an active medicine of orchid herb and juniper leaves and a preparation method thereof. Background technique [0002] Piglet diarrhea has plagued the development of pig industry for a long time and is one of the important factors restricting the development of pig industry. The cause of the disease is widespread and occurs all the year round. In the pig production process, the mortality rate of piglet diarrhea is high, the growth and development of resistant piglets are slow, and the feed utilization rate is low, causing major economic losses to breeding enterprises. At present, in the selection of drugs for the treatment of piglet diarrhea, antibiotics or synthetic antibacterial preparations are the most commonly used. Since long-term use of these drugs is likely to cause the emergence of drug-resistant strains, which is not conducive to the prevention and treatment o...

AI Technical Summary

Problems solved by technology

The cause of the disease is widespread and occurs all year round. In the process of pig production, the mortality rate of piglets with diarrhea is high, the growth and development of resistant piglets are slow, and the utilization rate of feed is low, causing major economic losses to the breeding enterprises.

At present, in the selection of drugs for the treatment of piglet diarrhea, antibiotics or synthetic antibacterial preparations are the most commonly used. Since long-term use of these drugs is likely to cause the emergence of drug-resistant strains, which is not conducive to the prevention and treatment of piglet diarrhea, therefore, Chinese herbal medicine additives are used to prevent piglet diarrhea. more and more research

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