A feed additive for repairing grass carp drug-induced liver injury and preparation method thereof

Abstract

The invention relates to a feed additive capable of restoring a drug-induced liver injury of a grass carp. The feed additive is prepared from by glutathione, vitamin C, vitamin E, organic selenium, Chinese wolfberry fruits, astragalus membranaceus, soybean protein powder and wheat middling; the ingredients are reasonably matched in a certain proportion for producing out the feed additive, when the feed additive is added to grass carp feed, glutamic oxalacetic transaminase, glutamic-pyruvic transaminase and malonaldehyde which rise to a high level in the body of the grass carp can be adjusted to the normal level, meanwhile, a good restoration effect is achieved on liver tissue pathological changes caused by drug-induced elements, and the feed additive is simple in preparation method.

Description

【Technical field】 [0001] The invention relates to a feed additive for grass carp, in particular to a feed additive for repairing drug-induced liver injury of grass carp and a preparation method thereof, belonging to the field of feed additives. 【Background technique】 [0002] Grass carp is the freshwater aquaculture species with the largest annual aquaculture output in my country. Common diseases during the aquaculture period mainly include bacterial diseases, viral diseases, parasitic diseases and other diseases. For the above three types of grass carp diseases, the breeding terminal mainly adopts drugs to prevent and control them. Bacterial diseases are mainly treated with oral antibiotics, viral diseases are mainly treated with Chinese herbal medicines and active substances, and parasitic diseases are mainly treated with oral administration Or splash chemical drugs for prevention and treatment. [0003] Fish liver is the metabolic center of nutrients in the body and play...

AI Technical Summary

Problems solved by technology

However, when the accumulation of drugs in the fish body exceeds the physiological load of the liver for drug metabolism and transformation, it will cause drug-induced damage to the grass carp liver, resulting in different degrees of energy and multiple nutrient metabolism disorders in the fish body

In recent years, due to the objective existence of drug resistance of grass carp-derived pathogenic bacteria and the subjective misunderstanding of drug use by breeding terminals, in order to better prevent and control the disease, drugs are used beyond the course of treatment and over the course of the disease. Phenomena such as recommended dosage and random compatibility are becoming more and more common in the breeding terminal, which has caused a series of indirect hazards. For example, during or after the medication period, the biological behavior of grass carp manifests as swimming fatigue, loss of appetite, and growth performance. Decreased, sensitive to environmental stress; pathologically manifested as yellow or white liver, green liver in severe cases, edematous widening of liver interstitial tissue, hepatocyte enlargement, degeneration, necrosis, etc.; in severe cases, grass carp Raise the bait coefficient and reduce the breeding benefit per mu

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