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Medical ultrasonic coupling agent and preparation method thereof

A technology of ultrasonic coupling agent and essential oil, which is applied in echo/ultrasonic imaging agents, medical preparations containing active ingredients, pharmaceutical formulas, etc. It can solve the problems of poor sound transmission effect and ultrasonic imaging effect, and few applications, so as to avoid crossover Infection, good coupling effect, good lubricating effect

Inactive Publication Date: 2015-12-16
乔芳霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there are products or technologies that use povidone-iodine to make gels, such as the invention patent CN102657600A, which discloses a veterinary povidone-iodine gel and its preparation process, but this type of gel is rarely used in ultrasound medicine , the effect of sound transmission and ultrasound imaging is relatively poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A medical ultrasonic coupling agent, which is made of the following raw materials by weight percentage: povidone iodine 0.1%, oleyl alcohol polyoxyethylene ether 0.02%, konjac gum 0.05%, aloe vera gel 0.05%, angelica essential oil 0.05%, longevity Chrysanthemum essential oil 0.05%, Houttuynia cordata essential oil 0.05%, polyethylene glycol 2%, potassium iodide 0.01%, carbomer 0.1%, triethanolamine 0.05%, angelica water extract 0.5%, dandelion water extract 0.5%, Panax notoginseng Water extract 0.5%, licorice water extract 0.5%, purified water.

[0017] The preparation method of described medical ultrasonic coupling agent, comprises the following steps:

[0018] (1) Add povidone-iodine and potassium iodide into an appropriate amount of purified water, fully dissolve to obtain aqueous solution A; add an appropriate amount of purified water to extract water extracts of angelica sinensis, dandelion, water extracts of Panax notoginseng, and water extracts of licorice, and f...

Embodiment 2

[0022] A medical ultrasonic coupling agent is made of the following raw materials by weight percentage: povidone iodine 0.5%, oleyl alcohol polyoxyethylene ether 0.25%, konjac gum 0.23%, aloe vera gel 0.35%, angelica essential oil 0.75%, longevity Chrysanthemum essential oil 0.75%, Houttuynia cordata essential oil 0.77%, polyethylene glycol 2.5%, potassium iodide 0.06%, carbomer 1%, triethanolamine 0.8%, angelica water extract 0.75%, dandelion water extract 0.75%, Panax notoginseng Water extract 0.75%, licorice water extract 0.75%, purified water.

[0023] The preparation method of the medical ultrasonic coupling agent described in this embodiment is the same as that in Embodiment 1.

Embodiment 3

[0025] A medical ultrasonic coupling agent is made of the following raw materials by weight percentage: povidone iodine 1%, oleyl alcohol polyoxyethylene ether 0.5%, konjac gum 0.5%, aloe vera gel 0.65%, angelica essential oil 0.1%, longevity Chrysanthemum essential oil 0.15%, Houttuynia cordata essential oil 0.1%, polyethylene glycol 5%, potassium iodide 0.1%, carbomer 2%, triethanolamine 1.55%, angelica water extract 1%, dandelion water extract 1%, Panax notoginseng Water extract 1%, licorice water extract 1%, purified water.

[0026] The preparation method of the medical ultrasonic coupling agent described in this embodiment is the same as that in Embodiment 1.

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PUM

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Abstract

The invention provides a medical ultrasonic coupling agent and belongs to the technical field of reagents for medical tests. The ultrasonic coupling agent is prepared from raw materials as follows: povidone iodine, oleic alcohol polyoxyethylene ether, konjac glucomannan, aloe gel, Chinese angelica essential oil, African marigold essential oil, heartleaf houttuynia herb essential oil, polyethylene glycol, potassium iodide, carbomer, triethanolamine, a Chinese angelica aqueous extract, a dandelion aqueous extract, a notoginseng aqueous extract, a liquorice aqueous extract and purified water. The ultrasonic coupling agent is free of cytotoxicity, irritation and sensitization to skin, free of bubbles, good in heat stability and good in biocompatibility, and cross infection during clinical ultrasonic tests is avoided; the ultrasonic coupling agent is good in lubrication property and easy to expand, has sterilization and anti-inflammatory functions, can soften, moisten and smoothen the skin and has effects of promoting blood circulation, removing blood stasis, relieving pain and removing swellings; the ultrasonic coupling agent has a good coupling function and is significant in transmission effect and clear in ultrasonic imaging.

Description

technical field [0001] The invention belongs to the technical field of medical examination reagents, in particular to a medical ultrasonic coupling agent and a preparation method thereof. Background technique [0002] Medical ultrasonic coupling agent is an ultrasonic neutral medium that needs to be used in the process of ultrasonic diagnosis and treatment to fill or coat between the radiating surface of the probe and the human epidermis and mucous membrane to transmit sound waves. Ultrasonic coupling agent plays a role in determining the quality and even success in ultrasonic diagnosis and treatment operations. In clinical applications, it not only acts as a sound-transmitting medium, but also acts as a lubricant. Not only its acoustic characteristics, but also the goal of safety and effectiveness. Among them, the effectiveness mainly focuses on the sound transmission effect, and the safety mainly focuses on the impact on human tissues and the prevention of cross-infection....

Claims

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Application Information

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IPC IPC(8): A61K49/22A61K36/886A61K36/896A61P17/00A61P31/02A61K31/79A61K33/18
Inventor 乔芳霞武晓莲王润
Owner 乔芳霞
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