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Composite chitosan application for medical use

A technology of chitosan and chitosan solution, applied in the fields of medical science, bandages, absorption pads, etc., can solve the problems of insignificantly promoting the healing function of wound tissue, and achieves the benefits of wound healing, good safety, and anti-oxidation. good performance

Active Publication Date: 2015-12-09
杭州烨强生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

No significant effect on promoting the healing function of wound tissue

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A kind of medical composite chitosan plaster, comprises non-woven fabric backing and gel inner layer, and described gel inner layer is prepared by following method:

[0028] (1) Chitosan is dissolved in the glacial acetic acid solution of mass concentration 1%, and the chitosan solution that makes chitosan mass concentration is 5%; Chitosan is made up of 30% high molecular weight chitosan by weight percentage It is mixed with 70% low molecular weight chitosan oligosaccharide, the viscosity average molecular weight of high molecular weight chitosan (commercially available) is 800,000, and the viscosity average molecular weight of low molecular weight chitosan oligosaccharide (commercially available) is 2000.

[0029] (2) Add poloxamer 407 (commercially available), carrageenan extract, spirulina extract and vitamin C to the chitosan solution, the amount of poloxamer is 20g / 100mL chitosan solution, carrageenan extract The dosage of spirulina is 6g / 100mL chitosan solution, ...

Embodiment 2

[0034] A kind of medical composite chitosan plaster, comprises non-woven fabric backing and gel inner layer, and described gel inner layer is prepared by following method:

[0035] (1) Chitosan is dissolved in the glacial acetic acid solution of mass concentration 1%, and the chitosan solution that makes chitosan mass concentration is 10%; Chitosan is made up of 30% high molecular weight chitosan by weight percentage It is mixed with 70% low molecular weight chitosan oligosaccharide, the viscosity average molecular weight of high molecular weight chitosan (commercially available) is 800,000, and the viscosity average molecular weight of low molecular weight chitosan oligosaccharide (commercially available) is 2000.

[0036] (2) Add poloxamer (commercially available), carrageenan extract, spirulina extract and vitamin C to the chitosan solution, the amount of gel is 15g / 100mL chitosan solution, the amount of carrageenan extract The chitosan solution is 3g / 100mL, the amount of s...

Embodiment 3

[0041] A kind of medical composite chitosan plaster, comprises non-woven fabric backing and gel inner layer, and described gel inner layer is prepared by following method:

[0042] (1) Chitosan is dissolved in the glacial acetic acid solution of mass concentration 1%, and the chitosan solution that makes chitosan mass concentration is 7%; Chitosan is made up of 30% high molecular weight chitosan by weight percentage It is mixed with 70% low molecular weight chitosan oligosaccharide, the viscosity average molecular weight of high molecular weight chitosan (commercially available) is 800,000, and the viscosity average molecular weight of low molecular weight chitosan oligosaccharide (commercially available) is 2000.

[0043] (2) Add poloxamer (commercially available), carrageenan extract, spirulina extract and vitamin C to the chitosan solution, the amount of gel is 18g / 100mL chitosan solution, the amount of carrageenan extract The chitosan solution is 5g / 100mL, the amount of sp...

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Abstract

The invention discloses a composite chitosan application for medical use, wherein the chitosan application comprises a non-woven fabric backings and a gel inner layer; the chitosan application is characterized in that the gel inner layer is prepared by a method comprising the following steps: (1) dissolving chitosan in a glacial acetic acid solution which is 1% in mass concentration so as to obtain a chitosan solution that the mass concentration of the chitosan is 5-10%; (2) adding a gel, a pelvetia silquosa extract, a spirulina extract and vitamin C to the chitosan solution, standing by at 4 DEG C for 12-16h and uniformly stirring; and (3) heating to 37-40 DEG C, preserving heat for 30-40min and coating an obtained mixture on an outer layer by virtue of a coating machine so as to obtain the gel inner layer. The chitosan application disclosed by the invention is antibacterial, moisture-preserving and non-adhesive; and the chitosan application is free from any toxic or side effect, and is capable of promoting the rapid healing of wound tissues and relieving the formation of scars.

Description

technical field [0001] The invention relates to an application, in particular to a medical composite chitosan application. Background technique [0002] Medical applicator is a product that covers wound tissue and is used to cover wounds after surgery. Traditional wound dressings have the following defects: [0003] 1. Ordinary gauze-like dressings: opaque, unable to observe changes in the wound surface; easy to adhere to the wound tissue, without the function of absorbing exudate and relieving pain, and need to be replaced frequently; Tissue adhesion will cause severe local pain and lead to re-trauma and bleeding; it is easy to form scars, which is not conducive to the effective and rapid healing of wound tissue. [0004] 2. Silicone hydrogel dressings: chemically synthesized substances with toxic and side effects, containing silicone, polyurethane, polyethylene oxide and polyvinyl alcohol, and metallic mercury. The texture is hard, unable to be bent arbitrarily, and rel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44
Inventor 吴炜张匀卢承志
Owner 杭州烨强生物科技有限公司
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