Traditional Chinese medicine for treating primary angle closed glaucoma and preparation method of traditional Chinese medicine

An angle-closure glaucoma, primary technology, applied in the field of pharmacy, can solve the problems of falling and rising, poor control of intraocular pressure, common complications, etc., and achieves the effect of good treatment, prevention and treatment of optic nerve damage, and definite curative effect

Inactive Publication Date: 2015-11-18
朱爱菊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after the operation, the intraocular pressure may be poorly controlled or rise again, and various postoperative complications are also common.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0043] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine. When the dosage form of the traditional Chinese medicine is a granule, the preparation method includes the following steps:

[0044] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , taking the filter residue as the solute, slowly percolating at a rate of 1-2 ml per minute by percolation method, collecting the percolating liquid, and then concentrating under reduced pressure to 50-60 ℃ under the vacuum degree of 0.06-0.09Mpa, the relative density is 1.04 The paste of ~1.10 is spray-dried, the inlet air temperature of the spray dryer is 160-175 °C, and the outlet air temperature is 80-85 °C, and then pulverized into powder to make dry paste powder;

[0045] ...

Embodiment 1

[0054] Example 1: Granules

[0055] Take 100g of dogtail, 180g of Baijie vine, 100g of Humulus japonicus, 210g of yarrow, 230g of Chuangu root, 160g of sorrel, 100g of Baiyaozi, 160g of tortoise, 260g of licorice, 170g of sorrel, 120g of grapefruit core, Panlong Qi 220g, Tribulus terrestris 260g, Palm Leaf Reed 260g and Juniper 220g;

[0056] Its preparation method comprises the following steps:

[0057] Step 1: Mix the raw medicinal materials according to the stated ratio, add 6 times alcohol concentration of 95% ethanol relative to the mixture, heat to boiling and reflux for 3 hours, filter, use the reflux liquid as the solvent and the filter residue as the solute, use The percolation method slowly percolates at a rate of 2ml per minute, collects the percolation liquid, and then decompresses and concentrates it under a vacuum of 0.08Mpa to a paste with a relative density of 1.07 at 55°C, spray drying, and the air inlet of the spray dryer The temperature is 170 °C, the air ...

Embodiment 2

[0059] Example 2: Oral liquid preparation

[0060] Take 130g of dogtail, 160g of Baijie vine, 130g of Humulus japonicus, 180g of yarrow, 260g of Chuangu root, 150g of sorrel, 120g of Baiyaozi, 140g of tortoiseshell, 280g of licorice, 150g of sorrel, 140g of grapefruit core, Panlong Qi 190g, Tribulus terrestris 290g, Palm Leaf Reed 240g and Juniper 240g;

[0061] Its preparation method comprises the following steps:

[0062] The first step is to mix the dogtail, Baijie vine, Humulus japonicus, yarrow, Kawaguchi root, sorrel, white medicine seed and tortoise flower, and add 5 times the alcohol concentration of the mixture to 65% ethanol for reflux extraction 4 times, 3 hours each time, filtered, the filtrates were combined, ethanol was recovered, and concentrated to a paste with a relative density of 1.31 at 70°C for later use;

[0063] The second step is to mix the remaining raw medicinal materials in proportion, add 3 times the amount of water relative to the mixture, boil f...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine for treating primary angle closed glaucoma and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following various raw herbal materials: macrostachys uraria herb, cyclea polytata, humulus scandens, alpine yarrow fruit, roots of coix lachryma-jobi L. var. ma-yuen Stapf., creeping oxalis, stephanotis, bitter citrus immature flower, liquorice tails, buckeye, pummelo seed, tsingling bergenia rhizome, siberian saltbush fruit, tigergrass and needle juniper. The traditional Chinese medicine has the advantages that with the aid of operative treatment of western medicines, the traditional Chinese medicine for treating the primary angle closed glaucoma has a good curative effect and little side effects according to the traditional theory of traditiona chinese medicines in China; and intraocular pressure of a patient can be controlled well on the basis of operative treatment, and injury of glaucoma optic nerve damage is prevented and treated, so that glaucoma can be treated well.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating primary angle-closure glaucoma and a preparation method thereof. Background technique [0002] Glaucoma is an eye disease in which the intraocular pressure is intermittently or continuously increased. Continuous high intraocular pressure can damage various parts of the eyeball and visual function. Glaucoma is one of the three major blindness diseases that cause blindness in humans, with an incidence of 1% in the general population and 2% after the age of 45. [0003] Glaucoma is mainly divided into congenital glaucoma, primary glaucoma, secondary glaucoma and mixed glaucoma. Primary glaucoma can be further divided into primary open-angle glaucoma and primary angle-closure glaucoma. Primary angle-closure glaucoma can be further divided into acute angle-closure glaucoma and chronic angle-closure glaucoma. Acute angle-closure glaucoma:...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P27/06
Inventor 朱爱菊卢德国
Owner 朱爱菊
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