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Traditional Chinese medicine gel used for treating qi stagnation and blood stasis type bedsore in clinical nursing

A qi stagnation and blood stasis type, gel technology, applied in aerosol delivery, drug combination, medical formula, etc., can solve the problems of complex ingredients, non-extraction, and difficulty in borrowing

Inactive Publication Date: 2015-11-11
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are problems such as extensive preparation process, unreasonable selection of matrix, and impenetrable research on transdermal absorption mechanism.
[0005] Due to the complex composition of traditional Chinese medicine compound preparations, multiple ingredients often play a therapeutic role together, usually no single pure product is extracted, and the dosage is generally large, so it is difficult to borrow an advanced new external dosage form for a while

Method used

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  • Traditional Chinese medicine gel used for treating qi stagnation and blood stasis type bedsore in clinical nursing
  • Traditional Chinese medicine gel used for treating qi stagnation and blood stasis type bedsore in clinical nursing
  • Traditional Chinese medicine gel used for treating qi stagnation and blood stasis type bedsore in clinical nursing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Prescription: 3 parts of clear ointment, 3.5 parts of chitosan, 6 parts of propylene glycol, 2.5 parts of azone, 3.5 parts of triethanolamine, 40 parts of ethanol, and 155 parts of water.

[0055] Prescription for clear ointment: 9 parts of Zizhu Ye, 12 parts of Zicao, 12 parts of Radix Paeoniae Rubra, 25 parts of Sijiqing, 12 parts of Dilu, 2 parts of Coptidis Rhizoma, 10 parts of Red Vine, 15 parts of Xingye Fangfeng, 9 parts of Liangmianzhen.

[0056] Preparation method: mix Zizhu Ye, Comfrey, Radix Paeoniae Rubra, Sijiqing, Dilu, Coptidis Rhizoma, Red Vine, Xingye Fangfeng, and Liangmianzhen, add water to decoct 2 to 3 times, each time the amount of water added is the raw material medicine 6 to 10 times the weight, decoct for 1 to 2 hours, filter; combine the filtrates, let stand, take the supernatant and concentrate to a relative density of 1.08 (measured at 60°C), add ethanol to make the volume percentage of ethanol up to 65%, after stirring evenly, alcohol precip...

Embodiment 2

[0059] Prescription: 3 parts of clear ointment, 3 parts of chitosan, 6 parts of propylene glycol, 3 parts of azone, 3 parts of triethanolamine, 35 parts of ethanol, and 140 parts of water.

[0060] Prescription for clear ointment: 10 parts of purple pearl leaves, 12 parts of comfrey, 15 parts of red peony root, 25 parts of Sijiqing, 15 parts of Dixie, 2 parts of coptis, 10 parts of red rattan, 12 parts of apricot leaf Fangfeng, and 8 parts of liangmianzhen.

[0061] Preparation method: mix Zizhu Ye, Comfrey, Radix Paeoniae Rubra, Sijiqing, Dilu, Coptidis Rhizoma, Red Vine, Xingye Fangfeng, and Liangmianzhen, add water to decoct 2 to 3 times, each time the amount of water added is the raw material medicine 6 to 10 times the weight, decoct for 1 to 2 hours, filter; combine the filtrates, let stand, take the supernatant and concentrate to a relative density of 1.06 (measured at 60°C), add ethanol to make the volume percentage of ethanol up to 68%, after stirring evenly, alcohol p...

Embodiment 3

[0064] Prescription: 3.5 parts of clear ointment, 4.5 parts of chitosan, 8 parts of propylene glycol, 3.5 parts of azone, 4.5 parts of triethanolamine, 42 parts of ethanol, and 160 parts of water.

[0065] Prescription for clear ointment: 12 parts of purple pearl leaves, 10 parts of comfrey, 15 parts of red peony root, 30 parts of Sijiqing, 15 parts of Dixie, 2.5 parts of coptis, 12 parts of red rattan, 15 parts of apricot leaf Fangfeng, 12 parts of Liangmianzhen.

[0066] Preparation method: mix Zizhu Ye, Comfrey, Radix Paeoniae Rubra, Sijiqing, Dilu, Coptidis Rhizoma, Red Vine, Xingye Fangfeng, and Liangmianzhen, add water to decoct 2 to 3 times, each time the amount of water added is the raw material medicine 6 to 10 times the weight, decoct for 1 to 2 hours, filter; combine the filtrates, let stand, take the supernatant and concentrate to a relative density of 1.10 (measured at 60°C), add ethanol to make the volume percentage of ethanol up to 570%, after stirring evenly, a...

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Abstract

The invention discloses traditional Chinese medicine gel used for treating qi stagnation and blood stasis type bedsore in clinical nursing. The gel comprises 1-10 parts of clear paste, 1-10 parts of chitosan, 3-15 parts of propylene glycol, 2-8 parts of azone, 1-5 parts of triethanolamine, 20-50 parts of ethyl alcohol and 80-200 parts of water. The clear paste comprises folium callicarpae pedunculalae leaves, lithospermum, red peony roots, folium ilicis purpurea, melastoma dodecandrum, coptidis rhizome, caulis sargentodoxae, herba pimpinellae and shinyleaf pricklyash roots. The gel has the functions of promoting blood circulation to remove blood stasis, clearing away heat and toxic materials, regulating qi-flowing for activating stagnancy, cooling blood and clearing away heat and dispersing blood stasis and promoting tissue regeneration. The gel regulates qi and blood according to main pathological links of the qi stagnation and blood stasis type bedsore, and finally achieves the aims of promoting tissue regeneration and gaining flesh. Meanwhile, the gel is uniform and fine, is easy to coat after being expanded, long in residence time, stable in release and good in stability, and the skin is not tightened.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating decubitus of qi stagnation and blood stasis type, in particular to a traditional Chinese medicine gel used in clinical nursing for treating decubitus of qi stagnation and blood stasis type. Background technique [0002] Decubitus ulcer is soft tissue necrosis caused by neurotrophic disorder, blood circulation disorder, local tissue continuous ischemia, and malnutrition. Elbows, sacrum, heels, etc. The reason for its occurrence is a complex pathological process caused by many factors, common factors are: compression, shear force and friction. Patients who have been bedridden for a long time are under pressure on the local tissue for too long; the shear force acts on the deep skin, causing the relative movement of the tissue, resulting in the obstruction of the blood supply in the relevant area. The skin is often su...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61K9/06A61K47/36A61P17/02
Inventor 不公告发明人
Owner QINGDAO YUNTIAN BIOTECH
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