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Functional food for preventing tumor and assisting in anti-tumor treatment and preparing method thereof

A functional food and anti-tumor technology, applied in food preparation, functions of food ingredients, food ingredients, etc., can solve the problem of low anti-tumor activity and achieve the effect of preventing cancer and metastasis

Inactive Publication Date: 2015-11-04
南京贝杉国际贸易有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term experiments have proved that β-D-glucans that are dominated by alternating 1,3 linkages on the polysaccharide backbone chain often have anti-tumor activity, while those linked by 1,6 have very low antitumor activity

Method used

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  • Functional food for preventing tumor and assisting in anti-tumor treatment and preparing method thereof
  • Functional food for preventing tumor and assisting in anti-tumor treatment and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 preparation method of the present invention

[0032] A preventive and auxiliary anti-tumor fungal polysaccharide functional food formula according to the present invention, the formula ratio of which is: lentinan 50-100 parts, antler mushroom polysaccharide 100-150 parts, basswood ganoderma polysaccharide 50-100 parts, gray Tree flower polysaccharide 100-150 parts, Agaricus blazei polysaccharide 100-150 parts.

[0033] Its preparation method comprises the following steps:

[0034] 1. Extraction of fungal polysaccharides

[0035] The raw materials used in the present invention are shiitake mushrooms and ganoderma lucidum provided by Jiangxi Kangdao Biological Co., Ltd., and antler mushrooms, frondosa frondosa and Agaricus blazei provided by Yancheng Shennong Health Food Co., Ltd.

[0036] Taking lentinan as an example to illustrate the extraction method of fungal polysaccharides.

[0037] Take an appropriate amount of shiitake mushrooms, wash them with ru...

Embodiment 2

[0043] Embodiment 2 mouse tumor suppression experiment

[0044] 1. Experimental animals and tumor strains

[0045] Experimental animals: Kunming mice, half male and half male, body weight (20±2)g

[0046] Tumor strain: S180 sarcoma, EAC tumor strain, H22 tumor strain

[0047] 2. Experimental method

[0048] S180 sarcoma inoculation: Extract the ascites of S180 tumor-bearing mice that will be passaged for 7 days under aseptic conditions, dilute the tumor cell suspension at a ratio of 1:3 with sterile 0.9% L sodium chloride solution, and take 40 mice of pure Kunming species. Each mouse was subcutaneously inoculated with 0.2 mL of S180 sarcoma cell suspension in the armpit of the right forelimb. 24 hours after tumor strain inoculation, they were randomly divided into four groups, 10 in each group, respectively marked as model control group, high-dose group, middle-dose group, and low-dose group, administered by intragastric administration, and the intragastric administration d...

Embodiment 3

[0058] Embodiment 3 crowd observation experiment

[0059] In order to verify the effect of the present invention, a crowd observation experiment was carried out.

[0060] Experimental population: 10 patients each with lung cancer, liver cancer and gastric cancer

[0061] Dosing method: The experimental population took this product while receiving conventional anticancer treatment, 2 times a day, 2 tablets each time, for 6 months continuously. During the period of taking, monitor the patient's physical condition, such as sleep status, food intake, and spirit, and regularly check the proliferation of cancer cells.

[0062] Experimental results:

[0063] Table 2 Statistics of crowd observation experiment results

[0064]

[0065] From the data in Table 2, it can be seen that the sleep condition, food intake, and mental state of the test population were basically maintained in a good state during the period of taking the present invention and cooperating with anticancer trea...

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Abstract

The invention belongs to the technical field of health-care food production, and particularly relates to functional food for preventing tumor and assisting in anti-tumor treatment and a preparing method thereof. The functional food comprises, by weight, 50-100 parts of lentinan, 100-150 parts of polysaccharide of antler mushrooms, 50-100 parts of polysaccharide of tilia ganoderma lucidum, 100-150 parts of polysaccharide of grifola frondosa and 100-150 parts of polysaccharide of afaricus blazei murill. According to the functional food and the preparing method, the polysaccharide of the five fungi which are high in anti-tumor activity are prepared according to the scientific ratio to make the functional food, according to the prepared fungal polysaccharide functional food, the immunity is enhanced to inhibit increase of tumor cells, promote apoptosis of the tumor cells and prevent transfer of the tumor cells, and meanwhile the functional food can assist in improving the chemoradiotherapy effect and lowering the side effect brought by chemoradiotherapy and besides can prevent normal cells from conducting canceration to achieve the function of preventing the canner.

Description

technical field [0001] The invention belongs to the technical field of health food production, and in particular relates to a functional food for preventing and assisting anti-tumor and a preparation method thereof. Background technique [0002] According to the "World Cancer Report" published by the World Health Organization in 2014, cancer has become the largest cause of death in the world, and the global incidence of cancer is severe, with morbidity and mortality continuing to rise, especially in developing countries. The number of new cancers in the world was 12.7 million in 2008, and it is expected to rise to more than 2 million by 2030. For my country, one person is diagnosed with cancer every 6 minutes, and 85.5 million people become cancer patients every day. One out of eight people dies from cancer, and finding effective ways to prevent and treat cancer is a top priority. The unique advantages of natural products in the prevention and treatment of various complex di...

Claims

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Application Information

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IPC IPC(8): A23L1/28A23L1/09
CPCA23V2002/00A23V2200/308A23V2250/51
Inventor 侯国新朱海伦傅庭治代然
Owner 南京贝杉国际贸易有限公司
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