Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Houttuynia eyedrop and preparation method thereof

A technology of Houttuynia cordata and eye drops, which is applied in the field of medicine, can solve problems such as uncertain efficacy of specific ingredients, difficulty in finding index ingredients, complex natural medicinal ingredients, etc., and achieve the effects of clear ingredients, convenient preparation, and stable quality

Active Publication Date: 2015-10-21
SICHUAN SUNNYHOPE PHARM CO LTD
View PDF2 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above reports only illustrate the main components of Houttuynia cordata. Due to the complex components of natural medicinal materials, it is impossible to determine the specific components that exert their medicinal effects. It is difficult to control the quality of the prepared preparations, and it is also difficult to find suitable index components for effective control.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Houttuynia eyedrop and preparation method thereof
  • Houttuynia eyedrop and preparation method thereof
  • Houttuynia eyedrop and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A kind of Houttuynia cordata eye drops, which is prepared by Houttuynia cordata extract as an active ingredient, plus pharmaceutically acceptable ophthalmic preparation auxiliary materials, the Houttuynia cordata extract contains 1 μg of methyl n-nonanone / ml, 4-terpineol 0.1μg / ml, ɑ-terpineol 0.01μg / ml, bornyl acetate 0.01μg / ml.

[0026] Wherein, the ophthalmic preparation auxiliary materials include surfactants, osmotic pressure regulators, bacteriostats, pH value buffers and antioxidants. The surfactant is Span; the osmotic pressure regulator is sodium chloride; the bacteriostatic agent is benzalkonium chloride; the pH buffer is phosphate; and the antioxidant is Vc. The pH value of the Houttuynia cordata eye drops is 5.

[0027] The preparation method of above-mentioned Houttuynia cordata eye drops, it may further comprise the steps:

[0028] S1. Soaking: take fresh Houttuynia cordata, add a sodium chloride solution whose volume is 1 times the weight of Houttuynia ...

Embodiment 2

[0033] A kind of Houttuynia cordata eye drops, which is prepared by Houttuynia cordata extract as an active ingredient, plus pharmaceutically acceptable ophthalmic preparation auxiliary materials, the Houttuynia cordata extract contains 10 μg of methyl n-nonanone / ml, 4-terpineol 10μg / ml, ɑ-terpineol 2.5μg / ml, bornyl acetate 2.5μg / ml.

[0034] Wherein, the ophthalmic preparation auxiliary materials include surfactants, osmotic pressure regulators, bacteriostats, pH value buffers and antioxidants. The surfactant is sorbitol; the osmotic pressure regulator is sodium chloride; the bacteriostatic agent is benzalkonium bromide; the pH buffer is citrate; the antioxidant is Vc - Palmitate. The pH value of the Houttuynia cordata eye drops is 7.

[0035] The preparation method of above-mentioned Houttuynia cordata eye drops, it may further comprise the steps:

[0036] S1. Soaking: Take fresh Houttuynia cordata, add a sodium chloride solution whose volume is 10 times the weight of Ho...

Embodiment 3

[0041] A kind of Houttuynia cordata eye drops, which is prepared by Houttuynia cordata extract as an active ingredient, plus pharmaceutically acceptable ophthalmic preparation auxiliary materials, the Houttuynia cordata extract contains 2 μg of methyl n-nonanone / ml, 4-terpineol 6 μg / ml, ɑ-terpineol 1.2 μg / ml, bornyl acetate 1.0 μg / ml.

[0042] Wherein, the ophthalmic preparation auxiliary materials include surfactants, osmotic pressure regulators, bacteriostats, pH value buffers and antioxidants. The surfactant is poloxamer; the osmotic pressure regulator is sodium chloride; the antibacterial agent is ethylparaben; the pH buffer is acetate; sodium bisulfite. The pH value of the Houttuynia cordata eye drops is 6.

[0043]The preparation method of above-mentioned Houttuynia cordata eye drops, it may further comprise the steps:

[0044] S1. Soaking: take fresh Houttuynia cordata, add a sodium chloride solution whose volume is 2 times the weight of Houttuynia cordata for soaki...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses houttuynia eyedrop and a preparation method thereof. The houttuynia eyedrop is prepared by houttuynia extract as an active ingredient and ophthalmic preparations auxiliary materials accepted pharmaceutically. The houttuynia extract contains 1-10 micrograms / ml of 2-undecanone, 0.1-10 micrograms / ml of 4-carvomenthenol, 0.01-2.5 micrograms / ml of alpha-terpineol and 0.01-2.5 micrograms / ml of bornyl acetate. The preparation method of the houttuynia eyedrop comprises the steps of soaking, distillation, redistillation and addition of auxiliary materials. The houttuynia eyedrop is definite in ingredient and stable and controllable in quality; the preparation method is easy to operate, the houttuynia eyedrop is convenient to prepare, and the houttuynia eyedrop and the preparation method thereof are suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to Houttuynia cordata eye drops and a preparation method thereof. Background technique [0002] Houttuynia cordata is the rooted whole plant of the perennial herbaceous plant Houttuynia cordata Thunb. of the family Tribaceae. It is famous for Pleurotus chinensis, Purple Houttuynia, Pig Nostril, Nine-section Lotus, etc. Its fresh plants have a pungent fishy smell after being broken. Widely distributed in the central, southeast and southwest provinces and autonomous regions of my country, especially in Hunan, Hubei, Sichuan, Jiangsu and other provinces. Houttuynia cordata has the effects of clearing heat and detoxifying, eliminating carbuncle and draining pus, diuresis and treating stranguria. Studies have shown that Houttuynia cordata contains volatile components, flavonoids, organic acids, sterols, alkaloids and other components. Houttuynia cordata is mainly eaten as a working ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/78A61K9/08A61P27/02
Inventor 黄莜萍王建波陈开军李涛程亮聂飞范世德胥勤
Owner SICHUAN SUNNYHOPE PHARM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com