TV-based 3D positron emission tomography (PET) image reconstruction method

Abstract

The invention discloses a TV-based 3D positron emission tomography (PET) image reconstruction method. The method includes the following steps that: (1) 3D projection data are obtained by using a PET 3D acquisition mode; (2) the 3D projection data are recombined to form 2D projection data; (3) reconstruction image frequency domain distribution is calculated from the 2D projection data; (4) total variation operators are added into a direct Fourier transform model, and a target function is established; (5) the above model is solved through adopting a BOSVS algorithm, so that 2D reconstruction results can be obtained; and (6) all 2D reconstruction results are merged so as to form a 3D reconstruction image. According to the method of the invention, based on direct Fourier transform, total variation is adopted as a regular term, so that the model can be constructed; the BOSVS algorithm is adopted to perform iteration solving, so that the reconstruction image with higher resolution and clearer edges can be obtained, and therefore, the quality of the reconstruction image can be significantly improved on the basis that direct Fourier transform rapid reconstruction is ensured, and better results can be obtained under low counting rate.

Description

technical field [0001] The invention belongs to the technical field of PET imaging, and in particular relates to a TV-based three-dimensional PET image reconstruction method. Background technique [0002] PET (Positron Emission Tomography) is positron emission computed tomography, as an advanced technology in the development of nuclear medicine, it has become a very important inspection method for cancer diagnosis, heart function detection and brain function imaging. It utilizes the advantages of many new technologies such as nuclear physics and medical imaging, and can observe the activities of cell metabolism at the molecular level. PET imaging technology is to inject a radioactive isotope that can directly or indirectly reflect the biological metabolic process in the living body, and receive the photon pairs generated by the annihilation through the detector ring in the PET device, and then calculate and determine the annihilation (emission) position of the positron. Fin...

AI Technical Summary

Problems solved by technology

The 3D acquisition mode removes the limitation of the metal partition between the detectors in the 2D mode, and considers the coincidence counts in all detector rings, which greatly improves the count rate of the projection data and the sensitivity of the detector, but in the 3D acquired data Contains more scattering, which requires a lot of calculation consumption and storage requirements for reconstruction and other processing

Due to the large amount of data collected and the slow reconstruction speed of 3D PET, how to improve the reconstruction speed of 3D PET while ensuring the reconstruction image accuracy has become one of the current research hotspots

Images