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Blood replenishing medicine composition and preparing method thereof

A composition and drug technology, applied in the direction of drug combination, medical formula, blood diseases, etc., can solve the problems of high price, complicated process, and insignificant effect, and achieve the effect of low cost, broad application prospect, and remarkable and reliable curative effect

Inactive Publication Date: 2015-07-29
汤晓
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are many drugs clinically used to replenish blood, but most of them have defects such as high price, complicated process, and insignificant effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A blood-enriching pharmaceutical composition, which is prepared from the following raw materials in weight ratio:

[0028] Angelica 45 parts, Ophiopogon japonicus 45 parts, Jujube 45 parts, Astragalus membranaceus 45 parts, Polygonum multiflorum 40 parts,

[0029] 40 parts of cinnamon, 40 parts of mulberry, 40 parts of privet fruit, 35 parts of raspberry, 35 parts of Atractylodes macrocephala,

[0030] 35 parts of papaya, 35 parts of licorice, 35 parts of poria cocos, 30 parts of dandelion, 30 parts of Sijiqing,

[0031] 30 parts of frankincense, 30 parts of rehmannia, 30 parts of comfrey, 25 parts of jujube seed, 25 parts of myrrh,

[0032] Guizhi 25 parts, Salvia miltiorrhiza 20 parts, Morinda officinalis 20 parts, Lycium barbarum 20 parts, Albizia juniper bark 20 parts, Coix seed 20 parts.

[0033] The preparation method of described pharmaceutical preparation is as follows:

[0034] Take by weighing above-mentioned crude drug according to above-mentioned weight f...

Embodiment 2

[0040] Toxicity test:

[0041] In this experiment, healthy SD rats were used, and the dosage gradient of the drug prepared in Example 1 was administered orally at 0.01g / kg and 0.1g / kg, and the drug was administered continuously for 30 days. Animal growth status, activity diet, hematology, blood biochemistry, organ tissue structure and urine routine were not significantly affected, indicating that the clinical medication is safe and reliable.

Embodiment 3

[0043] Summary of clinical efficacy:

[0044] General information, the pharmaceutical preparation of the present invention is applied to 98 cases of clinical observation, and all subjects are divided into 2 groups on average, control group and experimental group, each group of 49, two groups of cases in terms of gender, age, course of disease, etc. Analysis is comparable.

[0045] The diagnostic criteria formulated by WHO in 1972 considered that anemia was diagnosed when Hb was lower than the following levels in sea level areas: 110g / L for children aged 6 months to <6 years, 120g / L for children aged 6-14, 130g / L for adult males, and 130g / L for adults. 120g / L for women and 110g / L for pregnant women. It should be noted that the normal hemoglobin value of residents living in plateau areas is higher than that of sea-level residents; during pregnancy, hypoalbuminemia, congestive heart failure, splenomegaly, and macroglobulinemia, plasma volume increases, and even red blood cells ...

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PUM

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Abstract

The invention relates to a blood replenishing medicine composition and a preparing method thereof. The preparation is prepared from the following ingredients according to the mixture ratio: angelica, ophiopogon root, dates, milk veteh, radix-polygoni multiflori, cinnamon, mulberry fruit, fruit of glossy privet, raspberries, rhizoma atractylodis macrocephalae, pawpaw, liquorice, tuckahoe, dandelion, folium ilicis chinensis, frankincense, rehmanniae, lithospermum, wild jujube, myrrh, cassia twig, salvia miltiorrhiza, morinda officinalis, medlar, cortex albiziae and coix seeds. Various ingredients of the medicine are mutually matched and are coordinated to take effect, the cost is low, clinic use proves that the medicine has a good treatment effect on anemia, and the application prospects are wide.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a blood-tonifying medicinal composition and a preparation method thereof. Background technique [0002] Anemia refers to a common clinical symptom in which the volume of red blood cells in the peripheral blood of the human body is low, which is lower than the lower limit of the normal range. Because the determination of red blood cell volume is complicated, it is often replaced by hemoglobin (Hb) concentration in clinical practice. The main causes of anemia are: (1) iron deficiency; (2) decreased EPO production; (3) metabolic poisons inhibit the proliferation of red blood cells; (4) inflammatory factors accelerate the removal of antibodies or immune complexes in the circulation (5) The increased generation of reactive oxygen species in CKD patients makes red blood cells prone to hemolysis. Clinical manifestations: (1) Nervous system: dizziness, tinnitus,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P7/06
Inventor 汤晓刘梅霞
Owner 汤晓
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