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Functional medical dressing containing chitosan and hydrocolloid

A technology of hydrocolloid and chitosan, applied in medical science, absorbent pads, bandages, etc., can solve the problems of unsatisfactory hemostatic effect, poor healing ability, easy to fall off, etc.

Active Publication Date: 2015-07-22
武汉市思泰利医疗器械发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, hydrocolloid medical dressings on the market have problems such as poor ability to promote wound healing, unsatisfactory hemostatic effect, and poor shape retention, while chitosan medical dressings have poor skin adhesion and are easy to fall off after absorbing exudate. Problem, the present invention provides a chitosan functional hydrocolloid medical dressing that overcomes the defects of chitosan medical dressing and hydrocolloid medical dressing

Method used

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  • Functional medical dressing containing chitosan and hydrocolloid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041]Example 1: Put p-aminobenzoic acid into a three-necked bottle, add anhydrous ether, dissolve, then add a slight excess of thionyl chloride, put it in an ultrasonic cleaner, oscillate ultrasonically for 10 minutes, continue the reflux reaction and cool to room temperature After the reaction is completed, distill under reduced pressure until no liquid is evaporated, and after recrystallization, p-aminobenzoyl chloride is obtained. Add a certain amount of chitosan acetic acid solution with a concentration of 1% to the three-necked bottle, and then add p-aminobenzoyl chloride (the ratio of chitosan acetic acid solution to p-aminobenzoyl chloride is 3:1), The reaction was shaken and allowed to stand overnight. After the reaction is completed, add a large amount of acetone to precipitate the product, filter it with suction, soak it in a mixed solvent of absolute ethanol and anhydrous ether for 24 hours, then filter it with suction, and extract the filter cake with acetone for ...

Embodiment 2

[0042] Embodiment 2: formula is 16 weight parts SIS, 8 weight parts PIB1, 4 weight parts PIB2, 4 weight parts LIR-50, 10 weight parts guar gum, 14 weight parts CMC, 10 weight parts X-CMC, 5 weight parts Parts of chitosan, 15 parts by weight of rosin resin, 13 parts by weight of naphthenic oil, 1 part by weight of 1010.

Embodiment 3

[0043] Embodiment 3: formula is 18 weight parts SIS, 8 weight parts PIB1, 4 weight parts PIB2, 4 weight parts LIR-50, 10 weight parts guar gum, 14 weight parts CMC, 10 weight parts X-CMC, 5 weight parts Parts of aminobenzoyl chitosan derivatives, 15 parts by weight of rosin resin, 13 parts by weight of naphthenic oil, 1 part by weight of 1010.

[0044] Weigh various raw materials according to the formula described in Example 2 and Example 3, add rubber, tackifying resin, additives and other raw materials into the internal mixer, and vacuumize at a temperature of 135°C-160°C Mix for 20-30 minutes, when the temperature drops to 80°C-100°C, add neutral colloids, polyanion colloids, and polycation colloids, vacuumize and mix for 30-45 minutes, and then discharge, at a temperature of 70°C-90°C Next, use a vulcanizing machine to mold it into a sheet with a thickness of 1mm. One side is attached with a release paper or a release film, and the other side can be attached with a PU brea...

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Abstract

The invention relates to a functional medical dressing containing chitosan and hydrocolloid. The functional medical dressing comprises the following main components in percentage by weight: 10-40% of a polymer elastomer, 5-20% of tackifying resin, 5-15% of neutral hydrocolloid, 15-40% of polyanionic hydrocolloid, 3-15% of polycationic hydrocolloid and 5-25% of various additives. The functional medical dressing containing chitosan and hydrocolloid has very good performances such as breathability, absorptivity, softness, viscosity, skin fitness and the like, and chitosan added in the dressing has effects of resisting bacteria, diminishing inflammation, stopping bleeding and promoting wound healing. The dressing is particularly suitable for various scratches, burns, bedsores and operative wounds.

Description

technical field [0001] The invention relates to a hydrocolloid medical dressing, in particular to a chitosan functional hydrocolloid medical dressing. Background technique [0002] Hydrocolloid medical dressing is a high-tech wound healing material made by mixing water-soluble polymer particles with rubber. It is a very important type of wound dressing currently used in clinical care. [0003] The rubber component in the hydrocolloid medical dressing has a certain viscosity, which makes this kind of dressing easy to apply on the wound. The hydrocolloid fully expands after absorbing water, and its adhesive force decreases, making the adhesion between the hydrocolloid dressing and the wound Healing mainly occurs on the healthy skin around the wound; on the other hand, this type of dressing is highly hydrophilic, which can maintain a moist healing environment on the surface of the wound and absorb wound exudate, which can best protect the wound surface of fresh granulation tis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/32A61L15/24A61L15/42A61L15/44
Inventor 聂正稳李忠梅
Owner 武汉市思泰利医疗器械发展有限公司
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