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Superminiature preparation device of positron and molecular imaging labeled medicines

A technology for molecular imaging and preparation devices, which simplifies the maintenance process and is used in the field of preparation devices for rare isotopes (positron-labeled drugs), achieving the effects of reducing volume, reducing equipment availability problems, and improving magnetic field design

Inactive Publication Date: 2015-07-22
杭州科挚控制技术有限公司
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

And the operation is complicated, usually requires three professional operators (physicist, chemist and pharmacist)
[0007]High upfront costs, harsh installation conditions and complex and expensive operation and maintenance greatly limit the practical use of traditional medical cyclotrons
Without an accelerator, there would be no positron isotope-labeled drugs, which directly affects the promotion of PET / CT applications, prevents the majority of patients from enjoying the advanced diagnosis brought by molecular imaging technology, and limits the development of nuclear medicine in my country.

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  • Superminiature preparation device of positron and molecular imaging labeled medicines

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Embodiment Construction

[0025] The embodiment of the present invention is an ultra-miniaturized positron and molecular imaging labeling drug preparation device, which is composed of a cyclotron, a hot cell, a chemical synthesis module, a quality inspection system, and a packaging system. The isotopes produced by the cyclotron are put into the chemical synthesis module, reacted in the hot chamber, and synthesized into medical isotope-labeled drugs. After passing the quality inspection, they are put into special containers by the dispensing system and delivered to patients for use.

[0026] The cyclotron in this embodiment includes a magnet / power system, a cryogenic system, a radio frequency system, an ion source system, a vacuum system, a target system, a cooling system, and an integrated control system. The integrated control system adopts PLC and FPGA technology to fully manage other systems.

[0027] In the magnet / power supply system of the device of this embodiment, the magnet design adopts the superco...

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Abstract

The invention discloses a superminiature preparation device of positron and molecular imaging labeled medicines. The superminiature preparation device is composed of a circular accelerator, a hot cell, a chemistry synthesis module, a quality inspection system, and a subpackage system; isotopes generated by the circular accelerator are delivered into the chemistry synthesis module, and are subjected to reaction in the hot cell so as to obtain medical isotope labeled medicines via synthesizing; after quality testing, the qualified medical isotope labeled medicines are delivered into certain containers via the subpackage system, and then are given to patients for using; high-density coils, made of low-temperature superconducting materials or high-temperature superconducting materials, are adopted by the circular accelerator, and magnetized ferromagnetic mediums, such as electrotechnical soft iron or silicon steel sheet, are used as a supplement so as to obtain high-intensity magnetic fields; a complete closed-cycle subcooling condenser is used for refrigeration of the circular accelerator, and the superconducting coils can be immersed in liquid helium, or are subjected to conduction cooling without direct contact with liquid helium. Size and weight of the superminiature preparation device are reduced greatly; efficiency is increased greatly; and the superminiature preparation device is suitable for application in medical systems.

Description

[0001] technical field [0002] The invention relates to a rare isotope (positron-labeled drug) preparation device based on superconducting accelerator technology, which belongs to the field of high-end medical equipment. Background technique [0003] The development of molecular imaging technology provides the best means for early non-invasive diagnosis of cancer and heart disease, and the most representative technology is PET / CT. The full name of PET / CT is Positron Emission Tomography / X-ray Computed Tomography. This imaging technology is to inject a very small amount of positron isotope-labeled drugs into the human body, and then use an in vitro measuring instrument (PET) to detect the distribution of these positron-labeled drugs in various organs of the human body. It is one of the most advanced diagnostic imaging technologies to show the physiological and metabolic functions and structures of the main organs of the human body and the brain and heart. PET / CT is highl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K51/00
Inventor 彭晟姚治
Owner 杭州科挚控制技术有限公司
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