Alcohol-relieving medicine composition and preparation method thereof

A composition and anti-alcoholic technology, which is applied in the direction of drug combination, anti-drug, pharmaceutical formula, etc., can solve the problems of lack of products, accelerated ethanol metabolism, and single effect, so as to protect the liver, promote alcohol metabolism and excretion, and prevent drunkenness Effect

Active Publication Date: 2015-07-01
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current commercially available anti-alcoholic agents have the following deficiencies: the effect is relatively single, mostly acting on the liver metabolic enzyme system, accelerating the metabolism of ethanol to reduce the damage to tissues and cells, antagonizing the toxic effect of ethanol metabolism-related substances on the liver, However, there is a lack of products that can act on multiple links and have comprehensive effects.

Method used

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  • Alcohol-relieving medicine composition and preparation method thereof
  • Alcohol-relieving medicine composition and preparation method thereof
  • Alcohol-relieving medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
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specific Embodiment 1

[0047] The preparation of specific embodiment 1 extract dry powder

[0048] Pueraria japonica, Hovenia dulcis, hawthorn, Poria skin, reed root, tangerine peel, Schisandra chinensis, safflower, the raw materials are removed from the sundries and set aside. Take 4-8g of kudzu flower, 4-8g of Hovenia dulcis, 3-5g of hawthorn, 1-2.5g of poria cocos skin, 1-5g of reed root, 2-4g of tangerine peel, 3-5g of schisandra, and 0.1-0.25g of safflower. cook. For the first decoction, the soaking time of medicinal materials is 0.5-1.5 hours, the amount of water added is 8-12 times, and the extraction time is 1.0-2.0 hours. For the second decoction, add 6 to 10 times the amount of water, and the extraction time is 0.5 to 1.5 hours. Collect and combine the extracts that have been decocted for the second time, and the material-liquid specific gravity of the extracts is 1-2. Perform spray drying. The drying air inlet temperature is 180°C-210°C, the outlet air temperature is 80°C-110°C, the s...

specific Embodiment 2

[0049] The preparation of specific embodiment 2 granules

[0050] The dry powder obtained by spray-drying the extract of Example 1, adding an appropriate amount of absolute ethanol to granulate, passing through a 10-20 mesh sieve, drying in a constant temperature drying oven at 40-60°C for 3-4 hours, and then drying with a 10-20 mesh The granules are sieved to obtain granules, and the total flavonoids contained in the granules are not less than 1.5%.

specific Embodiment 3

[0051] The preparation of specific embodiment 3 buccal tablet

[0052] Spray-dry the obtained dry powder of the extract of Example 1, add magnesium stearate according to 2% of the dry powder mass, mix evenly, compress into tablets, and the pressure is 5-12KN to make buccal tablets, with a tablet weight of 0.5g, buccal tablets Containing total flavonoids is not less than 0.5%.

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Abstract

The invention discloses an lcohol-relieving medicine composition and a preparation method thereof. The composition is prepared from the following components in parts by weight: 3-12 parts of flos puerariae, 3-12 parts of hovenia dulcis thunb, 3-12 parts of hawthorn, 1-9 parts of poria bark, 2-9 parts of schisandra chinensis, 2-9 parts of rhizoma phragmitis, 2-12 parts of pericarpium citri reticulatae and 0.1-3 parts of safflower carthamus. The preparation method comprises the following steps: 1, removing impurities in the raw materials; 2, decocting for the first time to obtain primary extract; 3, decocting for the second time to obtain secondary extract; 4, mixing the primary extract and the secondary extract, and performing spray drying to obtain extract dried powder; and 5, molding, and manufacturing granules, tablets or effervescent tablets. According to the mechanism and approach of alcohol absorption, metabolism and excretion, natural medicinal and edible traditional Chinese medicinal materials are adopted as raw materials and are subjected to modern extraction technology and preparation technology to prepare granules, buccal tablets and effervescent tablets having excellent comprehensive alcohol relieving effect, safety and no toxic or side effect after being taken for a long time.

Description

technical field [0001] The invention belongs to the technical field of health care and relates to a hangover composition, in particular to a hangover composition and a preparation method thereof. Background technique [0002] According to reports, there are more than 500 million drinkers in China, who cannot avoid drinking in social communication, work entertainment, etc. Among them, 60% of the drinkers drink unhealthily and drink too much; 50% of the drinkers are in sub-health and poor health. below its level. Therefore, drunkenness often occurs, and the problem of hangover also arises from it. [0003] Excessive drinking can damage the gastrointestinal tract, liver, nerves, cardiovascular and cerebrovascular organs, and can lead to mental disorders, gastric ulcers, fatty liver, alcoholic hepatitis, and cirrhosis of the liver. [0004] China is the country with the highest incidence of liver cancer in the world. According to statistics, the incidence of liver cancer in my...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P39/00
Inventor 朱爱华张亚利杨钧李存张艺芳任雷何爱武
Owner 陕西中药研究所
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