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Preparation method of roselle antifatigue buccal tablet

A roselle anti-fatigue technology, applied in the field of preparation of roselle anti-fatigue buccal tablets, can solve the problems of incomplete release of active ingredients, many production process steps, high pollutant emissions, etc., and achieve the fragrance and sweetness of the preparation , less production process steps, low pollutant emissions

Active Publication Date: 2015-07-01
哈药集团中药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem of incomplete release of active ingredients in existing anti-fatigue health care products, low bioavailability after taking, discomfort caused by the adhesion of extracts and auxiliary materials to teeth and gums, restrictions on the occasions of taking some dosage forms, etc., and production There are too many process steps, high energy consumption, and relatively high pollutant discharge, thus providing a preparation method for anti-fatigue lozenges of roselle

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0017] Specific embodiment one: the preparation method of a kind of Roselle anti-fatigue lozenge of the present embodiment is to carry out according to the following steps:

[0018] 1. Sieving: take roselle flower extract powder, Roselle extract powder, basil extract powder, tortoise flower extract powder, erythritol, lactose, maltodextrin, glycyrrhizin, basil powder flavor 80 mesh sieve, polyethylene glycol 6000 through 200 mesh sieve;

[0019] 2. Weighing: Take the components sieved in step 1, and weigh them according to the following mass parts: 50-150 parts of Roselle extract powder, 30-130 parts of Roselle extract powder, 30-150 parts 130 parts of basil extract powder, 15-45 parts of tortoise flower extract powder, 110-320 parts of erythritol, 140-420 parts of lactose, 90-220 parts of maltodextrin, 0.5-1.5 parts Glycyrrhizin, 5-15 parts of basil powder essence and 20-60 parts of polyethylene glycol 6000;

[0020] 3. Raw material mixing: mix and stir the roselle flower e...

specific Embodiment approach 2

[0027] Specific embodiment 2: The difference between this embodiment and specific embodiment 1 is that the components described in step 2 after sieving in step 1 are weighed according to the following mass parts: 40-140 parts of roselle Extract powder, 20-120 parts of Rosa rufica extract powder, 20-120 parts of basil extract powder, 10-40 parts of tortoise flower extract powder, 100-300 parts of erythritol, 120- 400 parts of lactose, 80-200 parts of maltodextrin, 0.4-1.4 parts of glycyrrhizin, 3-10 parts of basil powder essence and 15-45 parts of polyethylene glycol 6000. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0028] Specific embodiment 3: The difference between this embodiment and specific embodiment 1 or 2 is that each component described in step 2 after sieving in step 1 is weighed according to the following mass parts: 60-160 parts Roselle extract powder, 40-140 parts of roselle extract powder, 40-140 parts of basil extract powder, 20-50 parts of tortoise flower extract powder, 120-350 parts of erythritol, 150-450 parts of lactose, 100-250 parts of maltodextrin, 0.6-1.6 parts of glycyrrhizin, 8-18 parts of basil powder essence and 30-70 parts of polyethylene glycol 6000. Others are the same as in the first or second embodiment.

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PUM

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Abstract

The invention relates to a preparation method of a roselle antifatigue buccal tablet, and relates to the preparation method of the tablet with the function of relieving physical fatigue. The invention aims to solve the problems that in the prior art, as extracts crudely extracted from medicinal material fine powders or raw medicinal materials are mostly used for preparing antifatigue preparations, and the adopted dosage forms are mostly capsules, medicinal liquor, oral liquid, particles, common tablets, beverage and the like, the medicine cannot carried or taken conveniently, the dosage is large, the taste is bad, the oral bioavailability is low, the medicinal liquor cannot be used conveniently during the work period and the like. The preparation method comprises the following steps of (1) sieving raw and auxiliary materials; (2) weighing the raw and auxiliary materials; (3) uniformly mixing the raw materials; (4) uniformly mixing the auxiliary materials; (5) uniformly mixing the raw materials and the auxiliary materials; (6) directly compressing to obtain the tablet. The roselle antifatigue buccal tablet prepared by refined extracts is fragrant, sour and sweet, and good in taste, has no gritty texture when being taken, is not adhered to gingival or teeth, is fresh and cool, does not easily induce decayed teeth, is high in oral bioavailability and quick in effect, and can quickly relieve the state of fatigue.

Description

technical field [0001] The invention relates to a preparation method of the anti-fatigue buccal tablet of the health product Roselle for relieving physical fatigue. Background technique [0002] Buccal tablets have the advantages of being easy to carry and take, and some drugs are absorbed through the mucous membrane without going through the first-pass effect of the liver, and have high bioavailability, fast onset of action, and good taste. Therefore, for the convenience of office workers to take conveniently at present, new preparations in the field of anti-fatigue health care are mostly made into buccal tablets. Roselle anti-fatigue lozenges have the functions of refreshing, stabilizing emotions, and relieving body fatigue. They are used for sub-health states, body fatigue, and mental fatigue, which lead to decreased work and study ability, reduced thinking ability, depressed mood, and inattention, etc. A range of fatigue manifestations. At present, due to the gradual i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23P1/02A61K36/752A61K9/20A61P39/00A23L33/00
Inventor 刘景国柳松林钮旭升广鸿雁苏德龙单钰毓曲林王丽娜李殿明王英新
Owner 哈药集团中药有限公司
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