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Hair-blacking traditional Chinese medicine composition as well as granules thereof

A composition and granule technology, which is applied in the field of UFA traditional Chinese medicine composition, to achieve the effects of uniform granules, less loss in the granulation process, and low moisture absorption rate

Active Publication Date: 2015-05-13
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main black hair products are to dye the hair black through hair dyes, and fail to solve the problem fundamentally

Method used

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  • Hair-blacking traditional Chinese medicine composition as well as granules thereof
  • Hair-blacking traditional Chinese medicine composition as well as granules thereof
  • Hair-blacking traditional Chinese medicine composition as well as granules thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Example 1: Extraction and purification process of flavored two to granules

[0054] According to the properties of the main active components of the medicinal materials, privetin and stilbene glycosides, which are easily soluble in ethanol, the extraction and investigation were carried out, and the main components of privet privet and the main components of stilbene glycosides in Polygonum multiflorum were selected as evaluation indicators , select the best extraction process (extraction process see figure 1 ).

[0055] method:

[0056] The making of the privetin standard curve:

[0057] Precisely draw 0.0408μg, 0.0816μg, 0.1632μg, 0.3264μg, 0.6528μg, 1.3056μg of the reference substance of privetin into the liquid chromatograph, take the content of the reference substance (X) as the abscissa, and take the peak area (Y) as the ordinate coordinates as a standard curve (see figure 2 ). The calculated regression equation is Y=3193005.971X-34289.284, r=0.9991.

[0058...

Embodiment 2

[0061] Embodiment 2: Granule molding process

[0062] Different excipients have different properties:

[0063] Dextrin: It dissolves slowly in cold water, easily soluble in hot water, insoluble in ethanol, and has strong cohesiveness.

[0064] Lactose: It is an excellent tablet filler. It is often crystalline lactose containing a part of water. It has no hygroscopicity, good compressibility, stable properties, no chemical reaction with most drugs, and the pressed tablets are smooth and beautiful.

[0065] Microcrystalline cellulose: It has good compressibility and strong binding force, and the compressed tablet has relatively high hardness. It can be used as a "dry binder" for direct compression of powder.

[0066] Sodium carboxymethyl cellulose: Carboxymethyl etherification of cellulose, insoluble in organic solvents such as ethanol and chloroform, when dissolved in water, the surface of the particles initially swells, and then water slowly penetrates into the interior and b...

Embodiment 3

[0087] Embodiment 3: granule molding process (drying temperature)

[0088] According to the above optimized process, take 100g of the extract prepared according to the method of Example 1, add 225g of lactose, 25g of sodium carboxymethylcellulose, mix and make soft material, granulate through a 20-mesh sieve, granulate through a 18-mesh sieve, and then use The traditional gradual heating method is used to dry the particles, that is, bake at 60°C for 30 minutes, bake at 70°C for 30 minutes, bake at 80°C for 30 minutes, and then cool down to 60°C with the same gradient to take out. The obtained soft material is "kneaded into agglomerates, lightly kneaded to disperse", and the obtained particles are dark brown, slightly sticky, with less loss, very little fine powder, and uniform particles.

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Abstract

The invention relates to a hair-blacking traditional Chinese medicine composition, application thereof as well as granules prepared from the composition. The hair-blacking traditional Chinese medicine composition is prepared from the following components in parts by mass: 20-50 parts of glossy privet fruit, 20-50 parts of eclipta, 10-30 parts of polygonum multiflorum, 10-40 parts of sealwort and 10-40 parts of black soya bean. The hair-blacking traditional Chinese medicine composition provided by the invention has the main benefits that the composition has the functions of nourishing liver and kidney, enriching and benefiting essence and blood and blacking hair and improving eyesight and is mainly used for deficiency of liver and kidney, insufficiency of blood and essence, premature graying of hair, dizziness and tinnitus and the like; the hair-blacking granules are relatively good in appearance, the granulating process is relatively less in loss, the granules are uniform, and the moisture rate is relatively low, and moreover, the hair-blacking traditional Chinese medicine composition is good in flowability, meets the basic standard of the granules, and is large in drug loading capacity, excellent in curative effect and convenient to carry and take.

Description

(1) Technical field [0001] The invention relates to an Ufa traditional Chinese medicine composition and application thereof, and Ufa granules prepared by using the composition. (2) Background technology [0002] At present, due to the accelerated pace of life, increased work pressure and mental pressure, serious lack of rest and sleep, and other factors, the nutrition required for hair is unbalanced, resulting in more and more young and middle-aged white-haired people, and its incidence rate is the highest among young and middle-aged people. Already higher than 15 to 32%. This disease has become an important factor affecting people's image and physical and mental health, and its etiology and pathogenesis are complicated, which are not clear yet. [0003] According to traditional Chinese medicine, gray hair is caused by deficiency of liver and kidney, insufficient production of qi and blood, lack of qi and blood to nourish hair, yin deficiency and internal heat, long-term yi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/16A61K47/38A61K47/26A61P17/00
Inventor 钟晓明余雪玲黄真任学聪赵静芳陈梦静
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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