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Method for rapidly and simultaneously detecting multiple indexes of fructus forsythia medicinal material

A detection method and multi-indicator technology, applied in measuring devices, analyzing materials, and analyzing materials through optical means, can solve problems such as few researches, improve production efficiency and economic benefits, shorten detection time, and ensure safety Effect

Active Publication Date: 2015-04-29
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are few relevant literature reports on the rapid detection of multi-index quality control content of Forsythia medicinal materials, especially the simultaneous rapid detection methods for the contents of rutin, forsythiaside A and forsythin

Method used

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  • Method for rapidly and simultaneously detecting multiple indexes of fructus forsythia medicinal material
  • Method for rapidly and simultaneously detecting multiple indexes of fructus forsythia medicinal material
  • Method for rapidly and simultaneously detecting multiple indexes of fructus forsythia medicinal material

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Example 1 : Method for fast detection of moisture in Forsythia medicinal material

[0043] (1) Near-infrared spectrum data collection of forsythia medicinal materials

[0044] After crushing 60 batches of Forsythia medicinal materials from different origins, they were passed through a 80-mesh sieve to obtain Forsythia medicinal powder with a relatively uniform particle size. The obtained Forsythia medicinal powder was precisely weighed 2 g, and placed in a flat bottle to keep the powder surface smooth. Near-infrared spectra were collected by the diffuse reflectance method. Spectral acquisition conditions: with air as a reference, the scanning range is 4000-12000 cm -1, the number of scans is 32, and the resolution is 8 cm -1 . The scanning of each batch of samples was repeated 3 times, and the average spectrum was taken. 60 batches of Forsythia medicinal material powder near-infrared original absorption spectra are attached figure 1 .

[0045] (2) Moisture dete...

Embodiment 2

[0060] Example 2 : Rapid detection method of forsythia medicinal material extract

[0061] (1) Near-infrared spectrum data collection of forsythia medicinal materials

[0062] After crushing 60 batches of Forsythia medicinal materials from different origins, they were passed through a 80-mesh sieve to obtain Forsythia medicinal powder with a relatively uniform particle size. The obtained Forsythia medicinal powder was precisely weighed 2 g, and placed in a flat bottle to keep the powder surface smooth. Near-infrared spectra were collected by the diffuse reflectance method. Spectral acquisition conditions: with air as a reference, the scanning range is 4000-12000 cm -1 , the number of scans is 32, and the resolution is 8 cm -1 . 60 batches of Forsythia medicinal material powder near-infrared original absorption spectra are attached figure 1 .

[0063] (2) Determination of extract content of Forsythia medicinal material:

[0064] Take 1 g sample and weigh it accurately ...

Embodiment 3

[0073] Example 3 : Rapid detection method for active ingredient content of Forsythia medicinal material

[0074] (1) Near-infrared spectrum data collection of forsythia medicinal materials

[0075] After crushing 60 batches of Forsythia medicinal materials from different origins, they were passed through a 80-mesh sieve to obtain Forsythia medicinal powder with a relatively uniform particle size. The obtained Forsythia medicinal powder was precisely weighed 2 g, and placed in a flat bottle to keep the powder surface smooth. Near-infrared spectra were collected by the diffuse reflectance method. Spectral acquisition conditions: with air as a reference, the scanning range is 4000-12000 cm -1 , the number of scans is 32, and the resolution is 8 cm -1 . 60 batches of Forsythia medicinal material powder near-infrared original absorption spectra are attached figure 1 .

[0076] (2) Simultaneous determination of the contents of rutin, forsythiaside A and forsythin in forsythi...

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Abstract

The invention relates to a method for rapidly and simultaneously detecting multiple indexes of a fructus forsythia medicinal material. The method comprises the following steps: collecting the fructus forsythia medicinal material; determining the content of rutin, forsythiaside A and forsythin by a high performance liquid chromatography; collecting near infrared spectrum data of fructus forsythia medicinal material powder, pretreating, building rapid detection models for the content of moisture, extractum, rutin, forsythiaside A and forsythin in the fructus forsythia medicinal material, wherein the built models are used for rapidly and simultaneously determining the content of various quality control indexes of the fructus forsythia medicinal material; and building a real-time release quantification standard. The method can be used for rapidly determining the content of the moisture, the extractum, the rutin, the forsythiaside A and the forsythin in the fructus forsythia medicinal material. Compared with a traditional method, the built analysis method and real-time release quantification standard are capable of relatively rapidly judging whether the quality of the medicinal material is qualified or not, and determining whether the medicinal material can enter the subsequent production process links or not, so that the rapid and high-efficiency scene requirements in practical production are met; and the method has an application prospect in producing medicinal material screening and comprehensive quality evaluation.

Description

technical field [0001] The invention belongs to the field of near-infrared process analysis and detection, and in particular relates to a multi-index simultaneous rapid detection method of forsythia medicinal material. Background technique [0002] forsythia for Forsythia suspensa (Thunb.) Vahl, a deciduous shrub, commonly known as a string of gold, is a plant of the genus Forsythia in the family Oleaceae. It mainly contains phenylethanol glycosides, lignans and their glycosides, pentacyclic triterpenes, volatile oils and other compounds. It has antibacterial, anti-inflammatory, antipyretic, antiemetic, diuretic and cardiotonic, anti-liver damage, analgesic, phosphodiesterase inhibitory, antiviral, blood pressure lowering, elastase activity inhibitory, and endotoxin-resistant effects. In addition to the fruit being used as medicine, it has the effects of clearing heat and detoxifying, eliminating stagnation and discharging pus, and its leaves are also effective in treatin...

Claims

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Application Information

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IPC IPC(8): G01N21/359G01N21/3563
Inventor 陈勇金叶耿姝吴永江刘雪松韩晓燕
Owner ZHEJIANG UNIV
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