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Feed additive capable of improving oxidative stress of dairy cows and application method of feed additive

A feed additive, oxidative stress technology, used in applications, animal feed, animal feed, etc.

Active Publication Date: 2015-03-25
HUNAN TAIFENG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional dairy cow health care and udder protection are dominated by antibacterial enhancement, which to a certain extent ignores the harm of oxidative stress to mammary gland health. The main means to effectively prevent oxidative stress is to feed antioxidants to dairy cows, but there is no direct way to prevent oxidative stress. Drugs or feed additives for antioxidant intervention on dairy cows are available on the market. Therefore, the applicant has developed a high-efficiency antioxidant preparation with a new component in view of the increasing demand for such products in the current market, which can prevent or alleviate the effects of Oxidative stress, corrects oxidative imbalance in dairy cows, protects mammary glands from oxidative damage, and improves milk production

Method used

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  • Feed additive capable of improving oxidative stress of dairy cows and application method of feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1. Weigh 50 portions of Pueraria lobata, 30 portions of buckwheat leaves, and 20 portions of licorice root, mix and crush them, pass through a 60-mesh sieve, reflux with 70% ethanol for 3 hours, filter, and concentrate and dry the filtrate at 45°C to obtain a compound extract of Pueraria lobata. The substance accounts for 1%-2% of the original drug.

[0018] 2. Pre-mixing Take 6g of compound pueraria lobata extract and 600g sepiolite; take 6.6g of vitamin A, 1.5g of vitamin E and 400g of chaff.

[0019] 3. Mixing Add 0.5g of tert-butyl hydroquinone to the above two pre-mixes and then stir to make the mixture uniform.

[0020] 4. The laboratory technician will inspect the mixing uniformity, effective substance content, moisture, and filling quantity.

[0021] 5. Packing and storage.

Embodiment 2

[0023] 1. Weigh 60 parts of Pueraria lobata, 25 parts of buckwheat leaves, 15 parts of licorice root, mix and pulverize, pass through a 60-mesh sieve, reflux with 80% ethanol for 2.5 hours, filter, and concentrate and dry the filtrate at 45°C to obtain a compound extract of Pueraria lobata. The substance accounts for 1%-2% of the original drug.

[0024] 2. Pre-mixing Take 8g of compound pueraria lobata extract and 700g sepiolite and mix; take 8.8g vitamin A, 2.5g vitamin E and 300g chaff.

[0025] 3. Mixing Add 1g of tert-butyl hydroquinone to the above two pre-mixes and then stir to make the mixture uniform.

[0026] 4. The laboratory technician will inspect the mixing uniformity, effective substance content, moisture, and filling quantity.

[0027] 5. Packing and storage.

Embodiment 3

[0029] Comparative study on antioxidant activity in vivo

[0030] 1. Materials and methods

[0031] 40 Chinese Holstein dairy cows with similar body weight, calving age, milk production and parity were selected and randomly divided into 4 groups. The control group was fed a basal diet. Under the same conditions, the test group 1 was added to the basal diet Vitamin E 100mg / day / head, test 2 groups add daidzein 400mg / day / head, test 3 groups add 50g / day / head of the additive prepared in Example 1 of the present invention, the test period is 20 days, and the test is collected twice before and after the test. Milk samples were tested for superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) activity and MDA value with a kit.

[0032] 2. Test results

[0033] It can be seen from Table 1 that there are significant differences between the additive group and the control group in various antioxidant indexes (P<0.01), while the vitamin E group and daidzein group are significantly different ...

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Abstract

The invention discloses a feed additive capable of improving oxidative stress of dairy cows and an application method of the feed additive. The feed additive is prepared from three plant extracts, two reductive vitamins and a carrier. Compared with a common dairy cow feed additive and a breast health medicine, the feed additive has a brand-new effect; the oxidative stress, caused by various stress sources, of the dairy cows can be resisted, and free radicals in a body are eliminated; and breast tissues are prevented from oxidative damages, the milk yield of the dairy cows is improved and the milk quality is improved.

Description

Technical field: [0001] The invention belongs to the field of feed additives, and specifically relates to a feed additive that can remove free radicals in dairy cows, resist oxidative damage, and improve the oxidative stress suffered by dairy cows and applications. Background technique: [0002] Dairy cows are prone to oxidative stress due to high-intensity metabolism. For example, the lactation period of dairy cows is as long as 300 days, and a large amount of milk is secreted every day. Material metabolism and oxygen consumption are both at very high levels, coupled with environmental stress. The addition of lipids in diets and diets makes dairy cows in a state of oxidative stress for a long time, which has a negative impact on their health and productivity. In particular, the mammary gland, as a common functional organ, has more serious oxidative damage. The incidence of mastitis is interrelated and directly leads to a decrease in lactation. Traditional dairy cow health care ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/16A23K1/18
Inventor 禹善秋
Owner HUNAN TAIFENG ANIMAL PHARMA
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