Traditional Chinese medicine composition for treating bone and joint tuberculosis, preparation method and combination of Chinese and Western medicines

A composition and joint technology, applied in the field of medicine, can solve problems such as long taking time, poor chemotherapy effect, abnormal liver function of patients, etc., achieve effects of less toxic and side effects, improve positive and negative effects, and be suitable for large-scale industrial production and application

Inactive Publication Date: 2015-01-21
HENAN UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, anti-tuberculosis drug chemotherapy currently advocates combination therapy, with isotonicum, rifampicin, and ethambutol as the first-line drugs, especially isotonicum and rifampicin as the first choice drugs, with the deterioration of the environment and the resistance of tuberculosis With the increase of drug strains, these anti-tuberculosis drugs have serious drug resistance problems, and the effect of chemotherapy is getting worse and worse, which has become a difficult problem in clinical treatment
At the same time, it is easy to cause abnormal liver function in patients due to the long time of taking the combined drug.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The traditional Chinese medicine composition that is used for the treatment of bone and joint tuberculosis in the present embodiment is made up of the raw material drug of following weight: Yunling 10 grams, Atractylodes macrocephala 15 grams, Codonopsis 10 grams, Radix Astragali 30 grams, Angelica sinensis 5 grams, Guizhi 15 grams , Platycodon grandiflorum 5 grams, Angelica dahurica 15 grams, red peony root 5 grams, white peony root 15 grams, saponins 5 grams.

[0038] The preparation method of the traditional Chinese medicine composition for the treatment of bone and joint tuberculosis in the present embodiment comprises the following steps: accurately take each raw material drug according to the weight part, add water and decoct 4 times, decoct for 2 hours each time, combine the decoction, Filtrate, take the filtrate and concentrate to a soft material with a relative density of 1.1 at room temperature, add an excipient 4 times the mass of the soft material (the excipi...

Embodiment 2

[0041] The traditional Chinese medicine composition that is used for the treatment of bone and joint tuberculosis in the present embodiment is made up of the raw material medicine of following weight: Yunling 10 grams, Atractylodes macrocephala 10 grams, Codonopsis pilosula 10 grams, Radix Astragali 15 grams, Angelica sinensis 5 grams, Guizhi 5 grams , 5 grams of bellflower, 5 grams of Angelica dahurica, 5 grams of red peony, 5 grams of white peony, 5 grams of fried saponins.

[0042] The preparation method of the traditional Chinese medicine composition for treating bone and joint tuberculosis in this example comprises the following steps: accurately take each raw material according to the weight part, add 3 times the amount of water to decoct and then concentrate to 300ml to obtain the oral liquid.

[0043] Usage and dosage of oral liquid: 1 dose per day, 100ml per dose, orally in 2 times.

Embodiment 3

[0045] The traditional Chinese medicine composition that is used for the treatment of bone and joint tuberculosis in the present embodiment is made up of the raw material medicine of following weight: Yunling 12 grams, Atractylodes macrocephala 12 grams, Codonopsis pilosula 12 grams, raw astragalus root 20 grams, angelica 10 grams, cassia twig 10 grams , 6 grams of bellflower, 10 grams of Angelica dahurica, 10 grams of red peony, 10 grams of white peony, 6 grams of fried saponins.

[0046] The preparation method of the traditional Chinese medicine composition for treating bone and joint tuberculosis in this example comprises the following steps: accurately take each raw material according to the weight part, add 4 times the amount of water to decoct and concentrate to 350ml to obtain the oral liquid.

[0047] Usage and dosage of oral liquid: 1 dose per day, 100ml per dose, orally in 2 times.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating bone and joint tuberculosis, a preparation method and a combination of Chinese and Western medicines, and belongs to the technical field of medicines. The traditional Chinese medicine composition is composed of the following raw materials by weight: 10-15 parts of poria, 10-15 parts of bighead atractylodes rhizome, 10-15 parts of radix codonopsis, 15-30 parts of raw radix astragali, 5-15 parts of angelica sinensis, 5-15 parts of cassia twig, 5-10 parts of radix platycodi, 5-15 parts of radix angelicae dahuricae, 5-15 parts of red peony root, 5-15 parts of white peony root and 5-10 parts of Chinese honeylocust spine. According to the theory of traditional Chinese medicine, the traditional Chinese medicine composition combines the medicines reasonably. For internal causes of the bone and joint tuberculosis, a plurality of qi-tonifying components such as the raw radix astragali, white peony root and angelica sinensis are used, which can effectively improve vital qi deficiency of a patient; and for external causes, the radix platycodi and Chinese honeylocust spine are used, which have good functions of activating blood to disperse swelling, and expelling toxin and pus. The traditional Chinese medicine composition has a definite curative effect, small toxic and side effect, can increase resistance of a patient by being taken for a long time, and can effectively treat the bone and joint tuberculosis.

Description

technical field [0001] The invention specifically relates to a traditional Chinese medicine composition for treating bone and joint tuberculosis, a preparation method of the traditional Chinese medicine composition, and a combination of Chinese and Western medicine for treating bone and joint tuberculosis, belonging to the technical field of medicine. Background technique [0002] Bone and joint tuberculosis is a purulent disease caused by Mycobacterium tuberculosis invading bone or joint. According to traditional Chinese medicine, its etiology and pathogenesis are nothing more than four aspects: one is the cold evil guest in the meridians, and the poisonous gas is trapped in the bones for a long time; Weakness; third, heavy loads, falls and injuries, resulting in disharmony of qi and blood, and re-infection of wind and cold, phlegm and turbidity, which remain in the bones; fourth, improper diet, qi stagnation and phlegm coagulation. In short, "deficiency is the root cause ...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P19/08A61P19/02A61P31/06A61K31/496A61K31/4409A61K31/133
CPCA61K36/076A61K9/0095A61K9/4866A61K31/133A61K31/4409A61K31/496A61K36/232A61K36/284A61K36/34A61K36/344A61K36/481A61K36/483A61K36/54A61K36/65A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 邱相君赵建龙李珂赵会军冯建芳吴银萍
Owner HENAN UNIV OF SCI & TECH
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