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Method for determining content of Astragaloside IV in traditional Chinese medicinal composition

A method of determination, the technology of astragaloside IV, is applied in the field of content determination of specific components in traditional Chinese medicine compositions, which can solve problems such as the lack of determination methods for the content of drug components, and achieve the effect of improving safety and reliability

Inactive Publication Date: 2015-01-14
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For this traditional Chinese medicine composition, only the medicinal ingredients and preparation method are disclosed at present, and the content determination method of the corresponding medicinal ingredients is not given

Method used

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  • Method for determining content of Astragaloside IV in traditional Chinese medicinal composition
  • Method for determining content of Astragaloside IV in traditional Chinese medicinal composition
  • Method for determining content of Astragaloside IV in traditional Chinese medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0079] The proportioning of this Chinese medicine composition is as follows:

[0080] Astragalus 700g, Ligustrum lucidum 140g, talc 140g, Prunella vulgaris 210g, litchi core 210g, amber 21g, cinnamon 28g, Phellodendron 70g.

[0081] The preparation process of this Chinese medicine composition capsule is:

[0082] (1) Take the above-mentioned Chinese medicinal materials, select them separately, crush them, and weigh them according to the prescription; (2) Take Astragalus membranaceus and Cortex Phellodendri, add 6 times the amount of 50% ethanol, heat and reflux for extraction once, each time for 0.5 hours, the extract Filtrate, merge, recover ethanol under reduced pressure, concentrate into a clear paste with a relative density of 1.2, put it into a vacuum drying oven, and dry under reduced pressure at a temperature of 60°C and a vacuum of 0.04Mpa, and the dry paste is ready for use;

[0083] (3) Take Ligustrum lucidum, add 6 times the amount of 70% ethanol, heat and reflux t...

Embodiment 2

[0095] The proportioning of this Chinese medicine composition is as follows:

[0096] Astragalus 140g, Ligustrum lucidum 25g, talc 25g, Prunella vulgaris 35g, lychee core 35g, amber 4g, cinnamon 5g, Phellodendron 15g.

[0097] The preparation process of this Chinese medicine composition tablet is:

[0098](1) Take the above-mentioned Chinese medicinal materials, select them separately, crush them, and weigh them according to the prescription; (2) Take Astragalus membranaceus and Cortex Phellodendri, add 70% ethanol, heat and reflux to extract 3 times, each time for 2 hours, filter the extract, and combine , after recovering ethanol under reduced pressure, concentrate it into a clear ointment with a relative density of 1.25, and set aside; (3) take Ligustrum lucidum, add 10 times the amount of 90% ethanol, heat and reflux for 3 times, and the time is 3 hours each time. Filtrate, combine, recover ethanol under reduced pressure, concentrate into a clear paste with a relative den...

Embodiment 3

[0112] The proportioning of this Chinese medicine composition is as follows:

[0113] Astragalus 350g, Ligustrum lucidum 90g, talc 90g, Prunella vulgaris 150g, litchi core 150g, amber 10g, cinnamon 20g, Cortex Phellodendri 50g.

[0114] The preparation process of this Chinese medicine composition pill is:

[0115] (1) Take the above-mentioned Chinese medicinal materials, select them separately, crush them, and weigh them according to the prescription; (2) Take Astragalus membranaceus and Cortex Phellodendri, add 60% ethanol, heat and reflux to extract twice, each time for 1 hour, filter the extract, and combine , after recovering ethanol under reduced pressure, concentrate it into a clear ointment with a relative density of 1.23 for later use; (3) take Ligustrum lucidum, add 8 times the amount of 80% ethanol, heat and reflux to extract twice, and the time is 2 hours each time. Filtrate, combine, recover ethanol under reduced pressure, concentrate into a clear paste with a rel...

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Abstract

The invention discloses a method for determining the content of Astragaloside IV in a traditional Chinese medicinal composition. The method concretely comprises the steps of preparing a tested substance solution, preparing a reference substance solution and determining. The determination method is helpful for controlling the quality of medicines, and improves the safety and the reliability of the medicines.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a method for determining the content of specific components in a traditional Chinese medicine composition. Background technique [0002] Traditional Chinese medicine has a history of thousands of years to treat diseases. With the development of science and technology, Chinese medicine is also facing modernization. To enter the world market, this requires that the quality control of Chinese medicine must be done well. The quality control of the composition content of Chinese medicine is It is the most critical, especially for compound traditional Chinese medicine preparations. In order to fully control the quality of traditional Chinese medicine, it is necessary to accurately measure the content of each component. [0003] The traditional Chinese medicine composition of the present invention is composed of astragalus, Ligustrum lucidum, talc, Prunella vulgar...

Claims

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Application Information

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IPC IPC(8): G01N30/02G01N30/06
Inventor 刘敏彦董超许红辉
Owner HEBEI YILING MEDICINE INST
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