Ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation

Abstract

The invention provides an ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation. High-low-frequency ultrasonic waves or low-high-frequency ultrasonic waves are sequentially transmitted by controlling a double-array-element annular con-focal power ultrasonic transducer in a time-sharing working mode or the ultrasonic transducer and phase-change micro-nano liquid drops are combined in use to achieve the purpose of improving ultrasonic mediated visco-elastic medium mechanical damage and thermal coagulation efficiency.

Description

technical field [0001] The invention relates to ultrasonic physics and ultrasonic instruments and applications thereof, in particular to an efficient ultrasonic mechanical damage and thermal coagulation device and method based on dual-frequency confocal ultrasonic time-sharing excitation. Background technique [0002] High-intensity focused ultrasound (HIFU), as a non-invasive ultrasound treatment technology, mainly utilizes the good tissue penetration and directionality of ultrasound to gather and form a high-intensity sound field in body tissues, through the transient high-temperature effect of ultrasound, The cavitation effect and mechanical effect destroy the target tissue in the focal region, but there is no damage to the tissue on the acoustic path and the surrounding tissue, so that the purpose of non-invasive treatment or surgical resection of the lesion can be achieved. According to its mechanism of action, HIFU damages the target tissue in two main ways: thermal ef...

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Problems solved by technology

However, HIFU still has certain limitations. The main point is that the thermal ablation or mechanical lesion produced by a single HIFU irradiation is small in size, and it takes a long time to ablate or destroy a larger tumor. It takes several hours, and it is difficult for the patient to remain still for such a long treatment time, which increases the risk and the incidence of complications

[0003] To address the above deficiencies, the most commonly used method is to increase the energy of HIFU. Although this method can expand the volume of ablation (or damage) lesions and shorten the treatment time, but at the same time, increasing the acoustic energy on the HIFU propagation path will affect the acoustic energy on the acoustic propagation path. causes extra damage to tissue, especially around the focal area, so this method is flawed

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