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Jiangzhining granule and preparation method thereof

A technology of Jiangzhining and granules, which is applied in the direction of medical formulas, medical preparations containing active ingredients, block delivery, etc. It can solve problems such as long disintegration time in the gastrointestinal tract, damage to the gastric mucosa, and difficulty in swallowing for patients. To achieve the effect of inhibiting the increase of serum cholesterol and the formation of atherosclerotic plaque, increasing coronary flow and dilating coronary vessels

Inactive Publication Date: 2014-12-03
TONGHUA XINDONGRI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Western medicines such as statins are very toxic. After taking them, they will not only damage the liver and kidneys, but also cause muscle pain, indigestion, skin rashes, etc.
[0004] Traditional Chinese medicines for lowering blood lipids in the market are mostly tablets, but the disintegration time in the gastrointestinal tract after oral administration is long, generally 15-20 minutes, which is easy to damage the gastric mucosa, and it is difficult for patients with swallowing difficulties to swallow

Method used

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  • Jiangzhining granule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take by weighing 500g of hawthorn (pitted), prepare 25g of Radix Polygoni Multiflori, 25g of Semen Cassiae, 75g of lotus leaf, decoct Hawthorn and Semen Cassiae with water for 2 hours each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.30( 50°C); the remaining lotus leaves and polygoni multiflorum were extracted three times with dilute ethanol under reflux, the first time was 3 hours, the second time was 2 hours, and the third time was 1 hour, the extracts were combined, ethanol was recovered, and concentrated to a relative density of 1. Combine the clear ointment of 22 (50°C) with the above-mentioned thick ointment, add 900g of sucrose, mix well, make 1000g, make granules, and dry to obtain.

[0018] Usage and dosage: take orally. 10g (1 bag) at a time, 3 times a day.

Embodiment 2

[0020] Take by weighing 500g of hawthorn (pitted), prepare 25g of Radix Polygoni Multiflori, 25g of Semen Cassiae, 75g of lotus leaf, decoct Hawthorn and Semen Cassiae with water for 2 hours each time, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.30( 50°C); the remaining lotus leaves and polygoni multiflorum were extracted three times with dilute ethanol under reflux, the first time was 3 hours, the second time was 2 hours, and the third time was 1 hour, the extracts were combined, ethanol was recovered, and concentrated to a relative density of 1. Combine the clear paste at 22 (50°C) with the above thick paste, add 310g of dextrin, mix well, make 400g, make granules, and dry to obtain (no sucrose).

[0021] Usage and dosage: take orally. 10g (1 bag) at a time, 3 times a day.

[0022] Application effect:

[0023] Get the Jiangzhining granule prepared by the method of Example 1 for clinical treatment.

[0024] 100 patients with hyper...

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Abstract

The invention discloses a Jiangzhining granule. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 25 to 27.5 parts of hawthorn, 1 to 1.25 parts of radix polygonum multiflorum preparata, 1 to 1.25 parts of semen cassiae and 3.25 to 3.75 parts of lotus leaves. The prepared Jiangzhining granule has functions of expanding coronary vessels, increasing coronary flow, reducing cholesterol absorption, accelerating cholesterol excretion, inhibiting the rising of serum cholesterol and the formation of atherosclerotic plaques, reducing blood fat and cholesterol and the like.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparation. More specifically, it relates to a Jiangzhining granule and a preparation method thereof. Background technique [0002] Cardiovascular disease is one of the most common and serious diseases that endanger human health (especially middle-aged and elderly people). Dyslipidemia is an important risk factor for atherosclerosis, coronary heart disease and other cardiovascular and cerebrovascular diseases. In recent years, hyperlipidemia has developed into a common disease in today's society, and with the improvement of people's living standards and changes in lifestyle, the incidence of hyperlipidemia is gradually increasing. Among adults over the age of 30 in the country, the incidence of hyperlipidemia is about 10%-20%, and the number of patients with hyperlipidemia is as high as 90 million. [0003] At present, there are many types of blood lipid-lowering drugs on t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K9/16A61P3/06
Inventor 崔永坤崔永佶
Owner TONGHUA XINDONGRI PHARMA CO LTD
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