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Medicine for treating ischemic stroke and preparation method thereof

A technology for ischemic stroke and drugs, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of poor clinical efficacy and no clinical reports of ischemic stroke drugs

Inactive Publication Date: 2014-02-12
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional Chinese medicine treatment methods for cerebral apoplexy mainly include the method of promoting blood circulation and removing blood stasis, promoting blood circulation and resolving phlegm, promoting qi and promoting blood circulation, regulating qi and resolving phlegm and promoting blood circulation, clearing heat, detoxifying and promoting blood circulation, and nourishing yin and promoting blood circulation. Most of the researches are based on "activating blood circulation and removing stasis" legislation, but the treatment is only based on "activating blood circulation and removing stasis", sometimes the clinical efficacy is not good
However, there are no relevant clinical reports on ischemic stroke drugs that treat phlegm and blood stasis at the same time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Raw material formula: Panax notoginseng 417g, scallions 277g, earthworm 277g, melon skin 277g, borneol 3g

[0022] Preparation Process:

[0023] Grind Panax notoginseng into fine powder (through a 80-mesh sieve) for later use; then mix scallions, earthworms and Trichosanthes skin, add 8 times the amount of water to decoct and extract 3 times, each time for 1 hour, filter, combine the filtrates, and concentrate to The clear ointment with a relative density of 1.10-1.12 (70°C) was left to cool, and 70% ethanol was added to make the alcohol content 60%, and it was left to stand for 24 hours, filtered, and the ethanol was recovered from the filtrate and concentrated to a relative density of 1.33-1.35 ( 70°C), add notoginseng fine powder and mix evenly, dry in a drying oven at 80°C until the water content is 5%, add borneol, pulverize in a pulverizer, pass through a 80-mesh sieve, add appropriate amount of starch to the total The weight is 500g, mixed evenly, packed into ca...

Embodiment 2

[0025] Raw material formula: with embodiment 1

[0026] Preparation Process:

[0027]Crush Panax notoginseng into fine powder (through 80-mesh sieve); take two-thirds of Panax notoginseng powder and add 6 times the amount of 70% ethanol, extract three times, combine the extracts, recover ethanol, and concentrate to a relative density of 1.33-1.35 (70°C) clear ointment for later use. The alcohol-extracted notoginseng dregs, scallion, earthworm, and gualou skin were decocted with 8 times the amount of water to extract 3 times, each time for 1 hour, filtered, and the filtrates were combined and concentrated to a relatively high temperature. The clear paste with a density of 1.33-1.35 (70°C) is combined with the notoginseng alcohol extract clear paste extracted in the first step and the remaining third of the fine powder of notoginseng, mixed evenly, and placed in a drying oven at 70-80°C Dry to a moisture content of 4%. Finally add borneol, pulverize, pass through an 80-mesh si...

Embodiment 3

[0029] Raw material formula: with embodiment 1

[0030] Preparation Process:

[0031] Crush one-third of Panax notoginseng into fine powder (through a 80-mesh sieve) for later use; decoct the remaining Panax notoginseng, scallion, earthworm, and melon skin with 8 times the amount of water to extract 3 times, 1 hour each time, filter After filtering, the filtrates were combined and concentrated to a clear paste with a relative density of 1.10 to 1.12 (70°C). Let it cool, add 70% ethanol to make the alcohol content 50%, let it stand for 24 hours, filter, recover ethanol from the filtrate and concentrate to Thick paste with a relative density of 1.33-1.35 (70°C), mixed with notoginseng crushed into fine powder, and dried in a drying oven at 70-80°C until the water content is 3%. Finally add borneol, pulverize, pass through an 80-mesh sieve, add an appropriate amount of starch to a total weight of 500g, mix well, pack into capsules, and make 1000 capsules to obtain the final prod...

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PUM

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Abstract

The invention discloses a medicine for treating ischemic stroke, which is prepared from the following main raw materials in parts by weight: 10-30 parts of panax pseudoginseng, 5-25 parts of allium macrostemon, 5-25 parts of lumbricus, 5-25 parts of pericarpium trichosanthis and 0.1-0.5 part of borneol. The raw materials of the product disclosed by the invention are widely available, the cost is relatively low, and the preparation process is simple; and the product has the functions of eliminating and dissipating phlegm and restoring consciousness and dredging vessels, and can improve the traditional Chinese medicine symptoms of a patient suffering ischemic stroke, reduce neurologic impairment and improve the activities of daily living and the like, thereby realizing a perfect curative effect on ischemic stroke.

Description

technical field [0001] The invention relates to a medicine for treating ischemic stroke and a preparation method of the medicine. Background technique [0002] Ischemic stroke is cerebral infarction. At present, the traditional Chinese medicine treatment methods for cerebral apoplexy mainly include the method of promoting blood circulation and removing blood stasis, promoting blood circulation and resolving phlegm, promoting qi and promoting blood circulation, regulating qi and resolving phlegm and promoting blood circulation, clearing heat, detoxifying and promoting blood circulation, and nourishing yin and promoting blood circulation. Most of the research on "activating blood circulation and removing stasis" legislates, but the treatment is only based on "activating blood circulation and removing stasis", and the clinical curative effect is sometimes not good. Clinically, the symptoms of patients with acute ischemic stroke include blood stasis, such as severe headache, pe...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P9/10A61K35/56A61K31/045A61K35/62
Inventor 刘泰
Owner GUANGXI UNIV OF CHINESE MEDICINE
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