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Soluble tilmicosin premix and preparation method thereof

A technology of tilmicosin and premix, which is applied in the directions of pharmaceutical formulations, organic active ingredients, medical preparations of non-active ingredients, etc., can solve the problem of not improving the anorexia of livestock and poultry, and not overcoming the bad odor irritation of tilmicosin. To achieve the effect of increasing bioavailability, improving bioavailability, and increasing dissolved concentration

Active Publication Date: 2014-12-03
GUANGDONG GALLOPER VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this patent application did not overcome the bad smell of tilmicosin and its irritation to the gastrointestinal tract, and did not improve the anorexia of livestock and poultry

Method used

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  • Soluble tilmicosin premix and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 Tilmicosin premix of the present invention and preparation method thereof

[0022] The soluble powder tilmicosin premix comprises the following components in parts by weight: 20 parts of tilmicosin; 10 parts of citric acid; 7 parts of lemon flavor; 63 parts of glucose.

[0023] The method for preparing the above product includes the following steps: 1) Accurately weigh the citric acid, lemon essence and tilmicosin after passing through a 40-mesh sieve according to the weight of the prescription, add the above components to a mixer for the first mixing, The mixing time is 20-30 minutes to obtain the first mixture; 2) After passing the glucose through a 40-mesh sieve, accurately weigh the glucose by weight of the prescription and add it to the first mixture for the second mixing. The mixing time is 30 -40 minutes, the second mixture is obtained; 3) The second mixture is subjected to quality inspection, and the finished product is obtained.

[0024] Among th...

Embodiment 2

[0025] Example 2 Tilmicosin premix of the present invention and its preparation method

[0026] The soluble powder tilmicosin premix comprises the following components in parts by weight: 18 parts of tilmicosin; 12 parts of citric acid; 10 parts of lemon essence; 60 parts of glucose.

[0027] The method for preparing the above product includes the following steps: 1) Accurately weigh the citric acid, lemon essence and tilmicosin after passing through a 40-mesh sieve according to the weight of the prescription, add the above components to a mixer for the first mixing, The mixing time is 20-30 minutes to obtain the first mixture; 2) After passing the glucose through a 40-mesh sieve, accurately weigh the glucose by weight of the prescription and add it to the first mixture for the second mixing. The mixing time is 30 -40 minutes, the second mixture is obtained; 3) The second mixture is subjected to quality inspection, and the finished product is obtained.

Embodiment 3

[0028] Example 3 Tilmicosin premix of the present invention and its preparation method

[0029] The soluble powder tilmicosin premix comprises the following components in parts by weight: 20 parts of tilmicosin; 15 parts of citric acid; 8 parts of lemon essence; 57 parts of glucose.

[0030] The method for preparing the above product includes the following steps: 1) Accurately weigh the citric acid, lemon essence and tilmicosin after passing through a 40-mesh sieve according to the weight of the prescription, add the above components to a mixer for the first mixing, The mixing time is 20-30 minutes to obtain the first mixture; 2) After passing the glucose through a 40-mesh sieve, accurately weigh the glucose by weight of the prescription and add it to the first mixture for the second mixing. The mixing time is 30 -40 minutes, the second mixture is obtained; 3) The second mixture is subjected to quality inspection, and the finished product is obtained.

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Abstract

The invention relates to a premix of a veterinary drug for livestock and a preparation method of the premix, and particularly relates to a soluble tilmicosin premix and a preparation method thereof, belonging to the field of veterinary drug processing, and aiming at overcoming the technical defects of low feeding rate of tilmicosin series of products and low utilization rate of tilmicosin in the feed in the prior art. The bad smell and the irritation of tilmicosin are covered in the premix, so that the stability of the drug is greatly improved, and the irritation to the stomach is reduced, the dissolution concentration of tilmicosin is improved, and the bioavailability of organism is greatly increased.

Description

technical field [0001] The invention relates to a veterinary drug premix for livestock and a preparation method thereof, in particular to a soluble tilmicosin premix and a preparation method thereof, belonging to the field of veterinary drug processing. Background technique [0002] As a major discovery in the development of human science and technology, antibiotics are a milestone in the fields of biology and medicine. Since the advent of penicillin in 1940, various synthetic and semi-synthetic antibiotics have emerged in an endless stream, becoming an important weapon to protect the health of human beings, animals and plants. The research and application of antibiotics are becoming more and more extensive, and they have played an important role in the prevention and control of animal diseases, improving feed utilization, and promoting the growth of livestock and poultry. [0003] Tilmicosin is a macrolide antibiotic semi-synthesized from tylosin, which is specially used f...

Claims

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Application Information

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IPC IPC(8): A23K1/16A61K31/706A61K47/26A61K47/12A61K47/46A61K47/36A61P31/04
Inventor 李云黄剑华
Owner GUANGDONG GALLOPER VETERINARY PHARMA
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