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Infantile common cold and cough syrup and preparation method thereof

A cold and syrup technology for children, which is applied in the field of medicine, can solve the problems of poor patient acceptance, slow drug absorption, and exacerbation of the disease, and achieve good curative effect, convenient transportation, and reduce the burden on patients

Active Publication Date: 2014-11-05
SHAANXI BICON PHARMA GRP HLDG COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In short, traditional Chinese medicine has achieved good curative effect in the treatment of this disease, but there are still some problems: traditional Chinese medicine is mainly based on Chinese patent medicines in the treatment of colds and coughs in children, which not only has large doses, slow drug absorption, and poor acceptance by patients. , not getting better for a long time, it will often delay the disease and make the disease worse

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  • Infantile common cold and cough syrup and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 A pediatric cold and cough syrup, in parts by weight (50g each), its components are: 1.2 parts of Kebiqing, 7 parts of ammonium chloride, 40 parts of pumila, 15 parts of gypsum, 320 parts of oligosaccharides, sodium benzoate 4 parts, 48 ​​parts licorice extract, the balance is water.

[0039] The method for preparing the above-mentioned pediatric cold and cough syrup is as follows:

[0040] (1) Crush the wild horse seed and the raw gypsum together, leaching with a 30% mass concentration of ethanol solvent according to the percolation method, obtain the liquid, recover the ethanol, and evaporate and concentrate to the volume (in milliliters) as the weight of the native drug ( In grams) 1.8 times.

[0041] (2) Mix the concentrated liquid obtained in step (1) with the licorice extract, and adjust the pH to 7.2 with sodium hydroxide.

[0042] (3) The oligosaccharides are first boiled with water, dissolved and filtered, and then the syrup is mixed into the mixed liquid ob...

Embodiment 2

[0045] Example 2 The preparation of children's cold and cough syrup (10g each): 1.8 parts of Kebiqing, 13 parts of ammonium chloride, 60 parts of pumila, 30 parts of gypsum, 420 parts of xylitol, 12 parts of sodium benzoate, 60 parts of licorice extract, The balance is water.

[0046] The method for preparing the above-mentioned pediatric cold and cough syrup is as follows:

[0047] (1) Crush the wild horse seed and the raw gypsum together, leaching with an ethanol solvent with a mass concentration of 80% according to the percolation method, obtain the liquid, recover the ethanol, and evaporate and concentrate to the volume (in milliliters) as the weight of the native drug ( In grams) 2.2 times.

[0048] (2) Mix the concentrated liquid obtained in step (1) with licorice extract, and adjust the pH to 8.5 with potassium hydroxide.

[0049] (3) Xylitol is first boiled with water, dissolved, filtered, and then the syrup is mixed into the mixed liquid obtained in step (2).

[0050] (4) Di...

Embodiment 3

[0053] Example 3 Preparation of pediatric cold and cough syrup (20g each): 1.4 parts of Kebiqing, 8 parts of ammonium chloride, 42 parts of Paomazi, 18 parts of gypsum, 360 parts of sucrose, 6 parts of sodium benzoate, 52 parts of licorice extract, the balance For water.

[0054] The method for preparing the above-mentioned pediatric cold and cough syrup is as follows:

[0055] (1) Crush the wild horse seeds and the raw gypsum together, leaching them with an ethanol solvent with a mass concentration of 35% according to the percolation method to obtain the liquid, recover the ethanol, and evaporate and concentrate to the volume (in milliliters) as the weight of the native drug ( In grams) 1.9 times.

[0056] (2) Mix the concentrated liquid obtained in step (1) with licorice extract, and adjust the pH to 7.5 with ammonia.

[0057] (3) The sucrose is first boiled with water, dissolved and filtered, and then the syrup is mixed into the mixed liquid obtained in step (2).

[0058] (4) Diss...

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Abstract

The invention discloses infantile common cold and cough syrup. The syrup is prepared from the following raw materials in parts by weight: 1.2-1.8 parts of carbetapentane citrate, 7-13 parts of ammonium chloride, 40-60 parts of manchurian lilac, 15-30 parts of gypsum, 320-420 parts of sucrose, 4-12 parts of sodium benzoate, 48-60 parts of liquid extract of liquorice and the balance of water. The syrup has the good effects that the product has good curative effects, takes an effect quickly and is safe and reliable; children make no resistance and are easy to feed; a process is simple and is easy in production operation; the syrup is convenient to store and transport; the medicine sources are accessible and the costs of the medicines are low, so that the burdens of patients can be reduced.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a cold and cough syrup for children and a preparation method thereof. Background technique [0002] Cold and cough in children is the most common type of disease in pediatrics. Its frequent season is mainly spring and winter. Studies believe that the disease is a type of exogenous disease caused by exogenous pathogens. The main clinical features of the disease include fever, nasal congestion, sneezing, and runny nose. Snot, cough, etc. These adverse symptoms have had a serious impact on the healthy development of children. Children are in the period of development and growth. It is believed in medicine that children have weak lung qi, delicate skin, weak defense, and immature immune system. Some external adverse factors such as weather changes and bacterial infections can easily cause children to catch a cold. The viscera are tender and weak, and adverse reactions s...

Claims

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Application Information

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IPC IPC(8): A61K36/63A61P11/00A61P11/14
Inventor 孙法峰
Owner SHAANXI BICON PHARMA GRP HLDG COMPANY
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