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Composition containing tangeretin for external application to the skin

A technology for external skin preparations and compositions, applied in the field of external skin preparation compositions, which can solve the problems of reduced antioxidant enzyme active oxygen defense ability, mutagenicity, toxicity, etc., achieve excellent skin erythema, improve skin tone, and prevent skin aging Effect

Inactive Publication Date: 2014-08-13
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the increase of age, the defense ability of antioxidant enzymes against active oxygen decreases, and synthetic antioxidants have been found to be mutagenic (mutage nicity) and toxic, so it is urgent to develop a safer and more effective natural antioxidant. oxidizing agent

Method used

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  • Composition containing tangeretin for external application to the skin
  • Composition containing tangeretin for external application to the skin
  • Composition containing tangeretin for external application to the skin

Examples

Experimental program
Comparison scheme
Effect test

reference example 1

[0067] [Reference Example 1] Preparation of Citrus Peel Extract

[0068]After the citrus peels are washed with pure water, they are dried. After pulverizing the citrus peels from which water has been removed, the active ingredients are extracted by cold-soaking extraction method at room temperature for 40-48 hours. The extracted content was filtered once with a 250 μm mesh, and then centrifuged to obtain the supernatant. Afterwards, the above-mentioned supernatant liquid was filtered sequentially with filter papers of 3 μm, 1 μm, and 0.5 μm. After adding 1,3-butanediol (1,3-Butylene glycol) 10%, phenoxyethanol (phenoxyethanol) 0.5%, ethylhexylglycerin (Ethylhexylglycerin) (Ethylhexylglycerin) 0.05%, and then filter with 0.2-0.3μm mesh filter paper, Thereby obtaining citrus peel extract.

reference example 2

[0069] [Reference Example 2] Preparation of Green Tea Extract

[0070] Green tea leaves are washed with pure water and then dried. After pulverizing the green tea leaves from which water has been removed, the effective components are extracted by cold soaking extraction method at room temperature for 40-48 hours. The extracted content is filtered once with a 250 μm mesh, and then centrifuged to obtain the supernatant. Afterwards, the above-mentioned supernatant was filtered sequentially with filter papers of 3 μm, 1 μm, and 0.5 μm mesh. After adding 10% of 1,3-butanediol, 0.5% of phenoxyethanol, and 0.05% of ethylhexylglycerin, the green tea extract was obtained by filtering with 0.2-0.3 μm filter paper.

reference example 3

[0071] [Reference Example 3] Preparation of Tangeretin

[0072] Tangeretin used in the present invention was purchased from Sigma-Aldrich.

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PUM

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Abstract

The present invention provides a composition containing tangeretin as an active ingredient for external application to the skin. The present invention also provides a composition containing tangeretin and EGCG for external application to the skin. The present invention also provides a composition for external application to the skin, comprising, as an active ingredient, mandarin peel extracts containing tangeretin. The present invention also provides a composition for external application to the skin comprising mandarin peel extracts containing tangeretin and further comprising green tea extracts containing Epigallocatechin gallate (EGCG). The composition has excellent antioxidative effects, and therefore can be applied as a cosmetic composition, a pharmaceutical composition or a health food composition. Furthermore, the composition may have superior effects of preventing skin erythema, improving skin tone and preventing skin aging.

Description

technical field [0001] The present invention relates to a composition for skin external application containing orange peel. Furthermore, the present invention relates to an external skin preparation composition containing tangeretin and epigallocatechin gallate (EGCG, Epigallocatechin gallate). Background technique [0002] All aerobic organisms, including humans, often produce reactive oxygen species damage in the process of using oxygen for energy metabolism, and the production of reactive oxygen species, which is basically beyond the self-defense capacity, has recently been recognized as an adult disease. Inflammation, circulatory system disorders, and even the etiology of various diseases such as senile dementia. [0003] Reactive oxygen species, generally considered to be harmful oxygen, are the most stable triplet oxygen ( 3 o 2 ) singlet oxygen generated during oxidation and reduction, such as superoxide anion ( 1 o 2 - ) and hydrogen peroxide (H 2 o 2 ), hydr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/353A61K36/752A61K31/35A61P17/00
CPCA61Q19/00A61Q19/08A61K8/498A61K8/97A61K2800/522A61P17/18A61K9/0014A61K31/352A61K36/752A61K36/82A61K2236/33A61K8/9789A61Q19/02A61K2236/51
Inventor 朴安娜金延埈
Owner AMOREPACIFIC CORP
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