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Composition containing tangeretin for external application to the skin

A technology for skin external preparations and compositions, applied in the field of skin external preparation compositions, can solve problems such as toxicity, mutagenicity, reduction of antioxidant enzyme active oxygen defense ability, etc., and achieves improvement of skin color, prevention of skin aging, and excellent skin erythema. Effect

Active Publication Date: 2017-12-01
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, with the increase of age, the defense ability of antioxidant enzymes against active oxygen decreases, and synthetic antioxidants have been found to be mutagenic (mutage nicity) and toxic, so it is urgent to develop a safer and more effective natural antioxidant. oxidizing agent

Method used

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  • Composition containing tangeretin for external application to the skin
  • Composition containing tangeretin for external application to the skin
  • Composition containing tangeretin for external application to the skin

Examples

Experimental program
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Effect test

reference example 1

[0068][Reference Example 1] Preparation of Citrus Peel Extract

[0069] After the citrus peels are washed with pure water, they are dried. After pulverizing the citrus peels from which water has been removed, the active ingredients are extracted by cold-soaking extraction method at room temperature for 40-48 hours. The extracted content was filtered once with a 250 μm filter bed, and then centrifuged to obtain the supernatant. Afterwards, the above-mentioned supernatant liquid was filtered sequentially through filters with meshes of 3 μm, 1 μm, and 0.5 μm. Add 10% of 1,3-butylene glycol, 0.5% of phenoxyethanol, and 0.05% of ethylhexylglycerin, and then filter with a 0.2-0.3μm mesh filter , so as to obtain the citrus peel extract.

reference example 2

[0070] [Reference Example 2] Preparation of Green Tea Extract

[0071] Green tea leaves are washed with pure water and then dried. After pulverizing the green tea leaves from which water has been removed, the effective components are extracted by cold soaking extraction method at room temperature for 40-48 hours. The extracted content is filtered once with a 250 μm filter bed, and then the supernatant is obtained through a centrifugation process. Afterwards, the above-mentioned supernatant liquid was filtered sequentially with filters of 3 μm, 1 μm, and 0.5 μm mesh. After adding 10% of 1,3-butanediol, 0.5% of phenoxyethanol, and 0.05% of ethylhexylglycerin, the green tea extract was obtained by filtering with a 0.2-0.3 μm filter.

reference example 3

[0072] [Reference Example 3] Preparation of Tangeretin

[0073] Tangeretin used in the present invention was purchased from Sigma-Aldrich.

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Abstract

The present invention provides a composition containing tangeretin as an active ingredient for external application to the skin. The present invention also provides a composition containing tangeretin and EGCG for external application to the skin. The present invention also provides a composition for external application to the skin, comprising, as an active ingredient, mandarin peel extracts containing tangeretin. The present invention also provides a composition for external application to the skin comprising mandarin peel extracts containing tangeretin and further comprising green tea extracts containing Epigallocatechin gallate (EGCG). The composition of the present invention has excellent antioxidative effects and therefore can be applied as a cosmetic composition, a pharmaceutical composition or a health food composition. Further, the composition of the present invention may have superior effects of preventing skin erythema, improving skin tone and preventing skin aging.

Description

[0001] This application claims priority to Korean Patent Application No. KR 10-2011-0136181, filed Dec. 16, 2011 and Korean Patent Application No. KR 10-2012-0146540, filed Dec. 14, 2012; this application is a 2012 A divisional application of Chinese Patent Application No. 201280061424.8 filed on December 17, 2012. technical field [0002] The present invention relates to a composition for skin external application containing orange peel. Furthermore, the present invention relates to an external skin preparation composition containing tangeretin and epigallocatechin gallate (EGCG, Epigallocatechin gallate). Background technique [0003] All aerobic organisms, including humans, often produce reactive oxygen species damage in the process of using oxygen for energy metabolism, and the production of reactive oxygen species, which is basically beyond the self-defense capacity, has recently been recognized as an adult disease. Inflammation, circulatory system disorders, and even ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/49A61Q19/00A61Q19/08
CPCA61Q19/00A61Q19/08A61K8/498A61K8/97A61K2800/522A61P17/18A61K9/0014A61K31/352A61K36/752A61K36/82A61K2236/33A61K8/9789A61Q19/02A61K2236/51
Inventor 朴安娜金延埈
Owner AMOREPACIFIC CORP
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