System and method for separating and removing circulating tumor cell and blood platelet in blood

Abstract

The invention discloses a system and method for separating and removing circulating tumor cell and blood platelet in blood, relates to the technical field of separation and removal of tumor cells, and aims at designing to solve the problems of poor effect on separating of circulating tumor cell, failure on blood platelet separation, failure on recycling of blood in the existing separating system. The system for separating and removing the circulating tumor cell and the blood platelet in the blood comprises a blood collecting device, a first micro-fluidic separating unit which is communicated with the blood collecting device through a pipeline, and a second micro-fluidic separating unit which is communicated with the first micro-fluidic separating unit through another pipeline; the first micro-fluidic separating unit is used for separating the circulating tumor cell in the blood; the second micro-fluidic separating unit is used for separating the blood platelet in the blood. The invention also provides a method for separating and removing the tumor cell and the blood platelet in the blood. With the adoption of the separating system, the circulating tumor cell and blood platelet in the blood of a patient with cancer can be effectively removed; the operation is simple and convenient; the separation effect is great; the spreading and metastasizing of cancer cells can be effectively controlled.

Description

technical field [0001] The invention relates to the technical field of tumor cell separation and removal, in particular to a system and method for separating and removing circulating tumor cells and platelets in blood. Background technique [0002] Cancer is one of the biggest killers that have seriously endangered human health in recent years, and the death rate it causes ranks among the top in every country in the world. With the development of medical technology, some progress has been made in the diagnosis and treatment of cancer, but most patients will experience recurrence and metastasis to varying degrees. Recent studies have shown that many factors affect the recurrence and metastasis of cancer, among which peripheral circulating tumor cells play a very important role. Circulating tumor cells are tumor cells that are shed from the primary tumor and invade the peripheral blood or lymphatic circulation. [0003] Since Ashworth first discovered tumor cells in the bloo...

AI Technical Summary

Problems solved by technology

At present, these methods generally have the disadvantages of low capture efficiency, cumbersome operation steps, low sensitivity, and easy irreversible damage to blood samples.

Due to the irreversible damage to the blood sample, the existing separation technology can only conduct preliminary analysis and detection of the blood, but cannot remove the tumor cells in all the blood of cancer patients, so the therapeutic effect cannot be achieved

Existing studies on circulating tumor cells still mainly focus on the separation, detection and analysis of circulating tumor cells. As an effective means of separation and removal, the research on removing all circulating tumor cells in blood has not been reported yet.

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