Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in preparing medicament for improving immunity of rabbits

A technology of immune performance and four gentlemen, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., and can solve problems such as the impact of rabbit immune performance

Inactive Publication Date: 2014-08-06
SOUTHWEST UNIVERSITY +1
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the impact of Sijunzi powder on the immune function of rabbits has not been reported.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in preparing medicament for improving immunity of rabbits
  • Application of codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in preparing medicament for improving immunity of rabbits
  • Application of codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in preparing medicament for improving immunity of rabbits

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Sixty New Zealand white rabbits aged 30 days after weaning were selected and randomly divided into 5 treatment groups according to the principle of similar body weight and half male and female. Each treatment had 3 replicates, and each replicate had 4 rabbits. The control group (processing 1) was fed the basal diet without adding any drugs, and the antibacterial drug group (processing 2) added sulfamethoxine sodium (SMD-Na) with a percentage by weight of 0.025% on the basal diet, and processing 3 Groups 1, 4, and 5 added 1%, 3%, and 5% Sijunzi powder to the basic diet respectively, and the feed was fully mixed evenly.

[0022] Feeding test: The feeding test was carried out in the special rabbit house of the agricultural and forestry pilot practice base of the university directly under the Ministry of Education of Southwest University. Free access to forage grass and drinking water was adopted. The immune disinfection procedure was carried out according to the conventiona...

Embodiment 2

[0042] According to the method of Example 1, Sijunzisan was mixed with the rabbit basal diet at the weight ratio of 5%, 3%, and 1%, respectively, and then re-granulated. Then select 36 healthy weaned rabbits, half male and half male, and then divide them into 4 groups (Sijunzisan high, medium and low dose groups and blank control group), each group has 3 repetitions, and each repetition has 3 rabbits. During the 30-day animal feeding experiment, body weight was weighed three times before, during and after feeding, and the daily gain of rabbits was calculated. The results are shown in Table 6.

[0043] Table 6. Average daily weight gain of rabbits

[0044]

[0045] The results showed that there was no significant difference in the average daily gain of rabbits in the high, medium and low dose groups, but the average daily gain of the medium dose group was 1 g greater than that of the blank group.

[0046]After the animal feeding experiment was over, the rabbits were dissect...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in preparing medicament for improving immunity of rabbits. According to the application, the codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder accounting for 1-5 percent of the weight of basic ration is added into the basic ration, the basic ration is fed to rabbits, and the rabbit sacculus rotundus index, thymus index, spleen index or dendritic index of a rabbit can be increased, the immunity of the rabbit can be improved, the expression quantity of an antifungal protein gene can be increased, and theoretical direction is provided to the codonopsis pilosula, rhizoma atractylodis macrocephalae, poria and liquorice powder in improving rabbit immunity.

Description

technical field [0001] The invention belongs to the field of application of traditional Chinese medicines, and in particular relates to the application of Sijunzi powder in the preparation of medicines for improving the immunity of rabbits. Background technique [0002] The end of the ileum of rabbits forms a thick-walled circular sac-like structure, called the round sac, which is a unique multifunctional organ integrating digestion, immunity and neuroendocrine in rabbits, and is also a unique intestinal-associated lymphoid tissue in rabbits. Studies have shown that a large number of antimicrobial peptides are found in the rabbit sac tissue. Scholars at home and abroad have actively explored the isolation and extraction of antibacterial active substances in rabbits. For example, in 1984, Selsted et al. used RP-HPLC combined with acid urea electrophoresis to purify six components of rabbit neutrophil defensins; in addition, Ooi et al. isolated an antibacterial protein with a ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61P37/04
Inventor 陈红伟吴俊伟李英伦刘娟黄庆洲
Owner SOUTHWEST UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com