Preparation method for heart-protecting musk pill-containing mixed medicament for preventing and treating coronary heart disease and cardiac failure

A technology of Shexiang Baoxin Pill and heart failure, applied in the field of traditional Chinese medicine, can solve the problem that it is difficult to effectively reduce the mortality and rehospitalization rate of heart failure in the elderly, the treatment status of heart failure has not been fundamentally improved, and it is difficult to effectively reduce the death of elderly heart failure. It can stabilize the atherosclerotic plaque, improve clinical symptoms and cardiac function indicators, and reduce the size of myocardial infarction.

Inactive Publication Date: 2014-07-16
田芳
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For a long time, drugs such as isosorbide dinitrate, metoprolol tartrate, furosemide, and captopril have been used to treat elderly heart failure. Although they have played a great role in the treatment of heart failure, the treatment status of heart failure It has not been fundamentally improved, and the treatment effect is not satisfactory. It is difficult to effectively reduce the mortality rate and rehospitalization rate of elderly heart failure patients. How to improve the quality of life, 5-year survival period and reduce rehospitalization rate of elderly patients with heart failure, and develop new and effective treatments Drugs for heart failure have become a major research topic in the cardiovascular field
[0005] The retrieved application number is 200510109554.6, which discloses a pharmaceutical composition for treating heart failure. It uses red ginseng, sun-burned astragalus, aconite, sun-burned epimedium, salvia miltiorrhiza, Chuanxiong, citrus citrus citrus, Radix Ophiopogon japonicus, and Tinglizi to treat heart failure in the elderly. The failure effect is not obvious, and it is difficult to effectively reduce the mortality rate of heart failure in the elderly

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The weight percentage of each component is 25-85% of Shexiang Baoxin Pills, 5-10% of isosorbide dinitrate, 6.25-25% of metoprolol tartrate, 10-40% of furosemide, and 10-40% of spironolactone. %, captopril 12.5%-50%, aspirin 15-70%, atorvastatin 10-20%, the sum of the above components by weight is 100%.

Embodiment 2

[0025] The weight percentage of each component is 26-75% of Shexiang Baoxin Pills, 5-9% of isosorbide dinitrate, 6.25-15% of metoprolol tartrate, 10-30% of furosemide, and 10-30% of spironolactone. %, captopril 14.5-50%, aspirin 15-65%, atorvastatin 10-20%, the sum of the above components by weight is 100%.

Embodiment 3

[0027] The weight percentage of each component is: Shexiang Baoxin Pills 28-85%, isosorbide dinitrate 5-9%, metoprolol tartrate 6.25-25%, furosemide 14-40%, spironolactone 10-34 %, captopril 12.5%-30%, aspirin 15-68%, atorvastatin 10-15%, the sum of the above components by weight is 100%.

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Abstract

The invention discloses a preparation method for a heart-protecting musk pill-containing mixed medicament for preventing and treating coronary heart disease and cardiac failure. On the basis of conventional therapy, a heart-protecting musk pill is added to treat coronary heart disease and cardiac failure, clinical symptoms and cardiac function indexes of patients are further improved, no obvious side effect exists, and the mixed medicament is effective and safe in treating coronary heart disease and cardiac failure. The cardiac function is improved by at least two levels after treatment, and the symptoms and signs are completely or partially remitted.

Description

Technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a method for assembling a mixed medicine containing Shexiang Baoxin pills for the prevention and treatment of coronary heart disease and heart failure. Background technique [0002] Heart failure refers to a syndrome of cardiac insufficiency caused by various heart diseases. In most cases, it refers to the decrease of myocardial contractility so that the cardiac output cannot meet the body's metabolic needs, and the blood perfusion of organs and tissues is insufficient. The performance of pulmonary circulation and (or) systemic circulation congestion. Heart failure is the terminal stage of various heart diseases. [0003] With the accelerated process of population aging and the increasing incidence of common cardiovascular diseases such as hypertension and coronary heart disease, the prevalence of heart failure is gradually increasing. According to statistics, the prevalence...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61P9/04A61P9/10A61K31/045A61K35/413A61K35/55A61K35/56A61K31/585A61K31/341A61K31/34A61K31/138A61K31/401A61K31/40A61K31/616A61K35/65
Inventor 田芳
Owner 田芳
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