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Traditional Chinese medicine preparation for treating central retinal vein occlusion

A retinal vein and traditional Chinese medicine preparation technology, applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve problems such as affecting vision and poor prognosis, and achieve the effects of improving vision, having no toxic side effects, and being convenient to take.

Inactive Publication Date: 2014-07-09
杨丽敏
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Ischemic patients are seriously ill and can lead to various serious complications such as neovascular glaucoma and cystoid macular edema, which seriously affect vision and poor prognosis

Method used

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  • Traditional Chinese medicine preparation for treating central retinal vein occlusion

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: take rehmannia glutinosa 30g, angelica 20g, red peony 15g, chuanxiong 10g, bupleurum 18g, bellflower 20g, aurantium citrus 20g, peach kernel 25g, turmeric 20g, salvia miltiorrhiza 18g, spatholobus 15g, medlar 15g, licorice 10g. Decoction in water, one dose per day, 15 days as a course of treatment. It is effective in the treatment of retinal vein occlusion.

Embodiment 2

[0032] Example 2: Take Rehmannia glutinosa 25g, Angelica 15g, Radix Paeoniae Rubra 10g, Ligusticum chuanxiong 8g, Bupleurum 12g, Platycodon grandiflorum 15g, Citrus aurantii 15g, peach kernel 20g, Curcuma 15g, Salvia miltiorrhiza 12g, Milletah 12g, Lycium barbarum 10g, licorice 6g.

[0033] Decoction in water, one dose per day, 15 days as a course of treatment. It is effective in the treatment of retinal vein occlusion.

[0034] Clinical Trials:

[0035] In order to verify the therapeutic effect of the present invention, in 2009~2011, the following clinical trials were carried out to the present invention in Liaocheng People's Hospital of Shandong Province:

[0036] 1. Materials and methods

[0037] 1.1 Diagnostic criteria

[0038] 1.1.1 Western medicine diagnostic criteria

[0039]Refer to "Ophthalmology" edited by Hui Yannian to determine the diagnostic criteria: 1. Sudden painless, non-progressive vision loss. 2. Fundus: optic disc edema, unclear boundary, flame-like ...

example 1

[0085] Example 1: Zhang, male, 56 years old, worker, first diagnosed in June 2010. Complaints of blurred vision in right eye for 2 months. The patient has a history of hypertension, generalized joint pain, red tongue, thin white fur, and astringent and weak pulse. Eye examination: visual acuity: right eye: L3.8, fundus optic disc hyperemia, blurred border, omentum scattered flame-like hemorrhage and hard exudation along the superior temporal vein. Fundus angiography showed retinal vein occlusion. A diagnosis of retinal superior temporal branch vein occlusion was made. Give treatment of the present invention, every day 1 dose, decoct in water. After taking 15 doses, the patient felt that the visual acuity of the right eye was improved, and the range of visual objects was expanded. Eye examination: visual acuity: right eye: L4.6, the optic disc of the fundus was clearer than before, most of the hemorrhage and exudation were absorbed, and the fundus angiography showed ischemia...

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Abstract

A traditional Chinese medicine preparation is prepared from the following raw materials by weight: 25-30 g of prepared rehmannia root, 15-20 g of angelica sinensis, 10-15 g of radix paeoniae rubra, 8-10 g of rhizoma chuanxiong, 12-18 g of radix bupleuri, 15-20 g of platycodon grandiflorum, 15-20 g of fructus aurantii immaturus, 20-25 g of semen persicae, 15-20 g of radix curcumae, 12-18 g of salvia miltiorrhiza, 12-15 g of caulis spatholobi, 10-15 g of fructus lycii, and 6-10 g of licorice. The traditional Chinese medicine preparation is capable of regulating liver and promoting qi circulation, promoting blood circulation to remove blood stasis, and improving eyesight and dredging collaterals, and plays a role in treating both symptoms and root causes on the retinal vein occlusion. The traditional Chinese medicine preparation has the following clinical effects: 1, the traditional Chinese medicine preparation effectively treats the retinal vein occlusion, the clinical healing and conspicuous effect rate is 66.6%, and the total clinical effective rate is 93.3%; 2, the traditional Chinese medicine preparation can improve eyesight, improves retinal microcirculation and retinal ischemia reperfusion, and promotes retinal hemorrhage and exudation absorption, so as to achieve the purpose of treating the retinal vein occlusion; and 3, the traditional Chinese medicine preparation is convenient to take, and has no toxic or side effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation made of pure Chinese medicines for treating retinal vein occlusion. Background technique [0002] Retinal vein occlusion is a relatively common retinal vascular disease. It is also one of the fundus diseases that cause blindness. Most occur in the elderly over the age of 50-60. Often monocular disease. The etiology of the disease is relatively complicated, and it is often closely related to hypertension, arteriosclerosis, hyperlipidemia, high blood viscosity, hemorheology and hemodynamics. Cardiac insufficiency, bradycardia, arrhythmia, and increased intraocular pressure can all be the cause of this disease in some patients. According to retinal ischemia, it is divided into ischemic type and non-ischemic type. Ischemic patients are seriously ill and can lead to various serious complications such as neovascular glaucoma a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P9/10A61P27/02
Inventor 杨丽敏林艳辉蔡新萌
Owner 杨丽敏
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