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Chewing gum capable of resisting oral helicobacter pylori, and preparation method thereof

A technology of Helicobacter pylori and chewing gum, applied in the field of chewing gum, can solve the problems of increasing treatment difficulty and medical cost, increasing the drug resistance of Helicobacter pylori, increasing the difficulty of treatment, etc., so as to reduce bacterial adhesion and aggregation, and inhibit and remove dental plaque. , The effect of taking the method is simple

Active Publication Date: 2014-07-02
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The prior art treats Helicobacter pylori by taking a variety of large doses of antibiotics. The disadvantages are: killing a large number of beneficial bacteria; increasing the drug resistance of Helicobacter pylori, increasing the difficulty of treatment and medical costs
In the prior art, antibiotics are added to chewing gum, which increases the drug resistance of Helicobacter pylori, increases the difficulty of treatment, and increases medical costs

Method used

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  • Chewing gum capable of resisting oral helicobacter pylori, and preparation method thereof
  • Chewing gum capable of resisting oral helicobacter pylori, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Embodiment 1: Preparation anti-oral HP chewing gum:

[0036] Take 2 kg of buckwheat glucoside, 0.01 kg of total alkaloids of flavescens, 0.25 kg of forsythiaside A and forsythiaside B, 0.3 kg of glycyrrhizin, 1 kg of tea polyphenols, 5 kg of milk protein, lanthanum bismuth phytate 0.01 kg, 0.004 kg of enzyme preparation, 22 kg of gum base, 34.88 kg of sorbitol, 12 kg of 75% hydrogenated starch hydrolyzate, 18 kg of xylitol, 3 kg of glycerin, and 3 kg of menthol for later use.

[0037] The preparation method is as follows: put the gum base in a kneader and knead for 1-2 minutes, then add the above-mentioned raw materials in turn, knead fully to make the lumps homogeneous, and the temperature is 45°C; take out the kneaded lumps and put them into the extruder Out of the machine, 15 ~ 20min extrusion molding.

[0038] The prepared anti-oral HP chewing gum takes 2-3 tablets per adult per day, and after taking it continuously for one month, the negative conversion of oral HP...

Embodiment 2

[0039] Embodiment 2: prepare the buccal tablet of anti-oral HP:

[0040] Take 2 kg of buckwheat glucoside, 0.01 kg of total alkaloids of matrine, 0.3 kg of glycyrrhizin, 1 kg of tea polyphenols, 0.01 kg of forsythiaside, 5 kg of milk protein, 0.01 kg of lanthanum bismuth phytate, 0.004 kg of enzyme preparation, 2.8 kg of menthol, 25 kg of sucrose, 5 kg of starch, 15 kg of maltodextrin, 45 kg of mannitol, 0.01 kg of magnesium stearate; 0.02 kg of micronized silica gel for use.

[0041]Add mannitol, sucrose, and starch to raw materials such as buckwheat glucoside, total alkaloids of matrine, tea polyphenols, forsythiaside, glycyrrhizin, milk protein, lanthanum bismuth phytate, enzyme preparation, and menthol, and mix well; The mixture is mixed with ethanol, then granulated, dried at 55-65°C, and the water content is reduced to 2%-4%, and the granules are obtained, and then flavored according to conventional techniques, magnesium stearate and micro-powdered silica gel are added, ...

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Abstract

The invention belongs to a chewing gum, and relates to a chewing gum capable of resisting oral helicobacter pylori (HP), and a preparation method of the chewing gum, aiming at overcoming the defects that in the prior art, the HP is treated by a large dose of antibiotic, so that a great deal of beneficial bacteria can be killed, and the drug resistance of the HP can be improved. The chewing gum comprises the following components in parts by weight: 1-2 parts of wild buckwheat glycoside, 0.005-0.015 part of total matrines, 0.1-0.6 part of forsythiaside, 0.1-0.5 part of glycyrrhizin, 0.5-1.5 parts of tea polyphenol, 3-6 parts of milk protein, 0.01-0.02 part of phytic acid lanthanum bismuth, 0.01-0.004 part of enzymic preparation, 20-22 parts of gum base, 34-34.88 parts of sorbitol, 12 parts of 75% hydrogenated starch hydrolysate, 16-18 parts of xylitol, 2.5-3.5 parts of glycerinum and 2.5-3.5 parts of menthol. The chewing gum has the advantages of being capable of effectively killing the oral HP and cariogenic bacteria and preventing dental caries, and being convenient to take.

Description

technical field [0001] The invention belongs to chewing gum, in particular to chewing gum against oral Helicobacter pylori and a preparation method thereof. Background technique [0002] Helicobacter pylori, referred to as HP, is an orally transmitted infectious disease. Oral HP is an important reservoir for gastric HP infection. The World Health Organization (WHO) lists Helicobacter pylori as the first carcinogen inducing gastric cancer. The detection rate of Helicobacter pylori in patients with gastric cancer in my country is 80%; in patients with chronic active gastritis, the detection rate is 95% to 100%; in patients with duodenal ulcer, the detection rate is 85% to 95%; It is detected in 70% to 80% of patients with gastric ulcer. In 1989, Australian scholar Krajden first detected HP from the dental plaque of the oral teeth of patients with gastritis, and confirmed that it was the same as HP in the stomach at the molecular level, proving that oral Hp is an important re...

Claims

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Application Information

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IPC IPC(8): A23G4/12
Inventor 卞雪莲郁世芳徐春芬刘娟叶佩华张静盛铀
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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