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Enteric capsule for treating chronic atrophic gastritis and preparation method thereof

A technology of atrophic gastritis and enteric-coated capsules, which is applied in the field of medicine, can solve problems such as single mechanism of action, loss of advantages of traditional Chinese medicine compound in treating and preventing diseases, and limited effect, and achieve remarkable effects, no toxic side effects, and low cost

Inactive Publication Date: 2014-05-21
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the common western medicines in clinical application are: teprenone, rebamipide, sucralfate, aluminum carbonate, etc., the mechanism of action of the above-mentioned medicines is single, and the effect is limited. Lost the advantages of traditional Chinese medicine compound prescriptions in treating and preventing diseases

Method used

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  • Enteric capsule for treating chronic atrophic gastritis and preparation method thereof

Examples

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Effect test

Embodiment 1

[0025] Herbal medicine prescription: 28 parts of Atractylodes macrocephala, 30 parts of Evodia, 15 parts of ochre, 15 parts of Cyperus cyperi, 30 parts of Polygonatum odoratum, 15 parts of Sanleng, 18 parts of angelica, 13 parts of curcuma, 0.06 parts of tea polyphenols, and 0.06 parts of allicin.

[0026] Preparation process: Weigh Atractylodes macrocephala, Evodia rutaecarpa, Daich, Rhizoma Cyperi, Polygonatum Polygonatum, Sanleng, Angelica and Curcuma, add 12 times the amount of water, soak for 14 hours, then decoct three times, decoct for 1.5 hours for the first time, filter out The liquid medicine is ready for use; add 9 times the amount of water for the second time, decoct for 1.2 hours, filter out the medicine liquid for use; add 8 times the amount of water for the third time, decoct for 0.8 hours, filter out the medicine liquid for use; combine Decoct the liquid three times, filter, and collect the filtrate; concentrate the filtrate to a thick paste with a relative dens...

Embodiment 2

[0028] Prescription of raw medicine: 23 parts of Atractylodes macrocephala, 28 parts of Evodia, 12 parts of ochre, 12 parts of Cyperus cyperi, 38 parts of Polygonatum odoratum, 15 parts of Sanleng, 25 parts of angelica, 16 parts of Curcuma, 0.06 parts of tea polyphenols, and 0.06 parts of allicin.

[0029]Preparation process: Weigh Atractylodes macrocephala, Evodia rutaecarpa, Daich, Rhizoma Cyperi, Polygonatum Polygonatum, Sanleng, Angelica and Curcuma, add 11 times the amount of water, soak for 16 hours, then decoct three times, decoct for 2 hours for the first time, and filter out the medicine Add 9 times the amount of water for the second time, decoct for 1.5 hours, and filter the medicinal solution for later use; add 8 times the amount of water for the third time, decoct for 1 hour, and filter the medicinal solution for later use; combine three decoctions liquid, filter, and collect the filtrate; the filtrate is concentrated to a thick paste with a relative density of 1.3,...

Embodiment 3

[0031] Prescription of herbal medicine: 35 parts of Atractylodes macrocephala, 23 parts of Evodia rutaecarpa, 18 parts of ochre, 15 parts of Cyperus cyperi, 25 parts of Polygonatum odoratum, 12 parts of Sanleng, 25 parts of angelica, 10 parts of curcuma, 0.06 parts of tea polyphenols, and 0.06 parts of allicin.

[0032] Preparation process: Weigh Atractylodes macrocephala, Evodia rutaecarpa, Daich, Rhizoma Cyperi, Polygonatum Polygonatum, Sanleng, Angelica and Curcuma, add 12 times the amount of water, soak for 15 hours, then decoct three times, decoct for 1.5 hours for the first time, filter out The medicinal solution is set aside; the second time, add 8 times the amount of water, decoct for 1 hour, and filter the medicinal solution for later use; decoction, filter, and collect the filtrate; the filtrate is concentrated to a thick paste with a relative density of 1.3, and baked at a low temperature for 7 hours to obtain a dry paste powder: add auxiliary materials according to ...

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Abstract

The invention discloses an enteric capsule for treating chronic atrophic gastritis and a preparation method thereof. The active ingredients contained in the capsule are prepared from the following Chinese herbal medicine materials in parts by weight: 23-38 parts of rhizoma atractylodis macrocephalae, 23-38 parts of fructus evodiae, 12-20 parts of ruddle, 12-20 parts of rhizoma cyperi, 23-38 parts of radix polygonati officinalis, 12-20 parts of rhizoma sparganii, 15-25 parts of angelica sinensis, 10-16 parts of curcuma zedoary, 0.05-0.1 parts of tea polyphenol and 0.05-0.1 parts of allicin. The traditional Chinese medicine enteric capsule disclosed by the invention is especially applicable to treatment of chronic atrophic gastritis of which helicobacter pylori infection is negative.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an enteric-coated capsule for treating chronic atrophic gastritis and a preparation method thereof. Background technique [0002] Chronic atrophic gastritis (CAG) has been defined by the WHO as a precancerous state of the stomach. In 1990, the World Congress of Gastroenterology Society reported that the 10-year cumulative risk rate of gastric cancer in patients with chronic gastritis with severe atrophy was 4%-30%. Mucosa <1%. In 2011, a cross-sectional survey in my country showed that the proportion of CAG in patients with chronic gastritis confirmed by gastroscopy was as high as 23.2%. Reversing the occurrence and development of CAG and blocking its evolution to gastric cancer have gradually attracted attention. [0003] The etiology of chronic atrophic gastritis mainly includes: HP infection, genetic factors, smoking and drinking, non-steroidal anti-inflammat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61P1/04A61K33/26A61K31/255
Inventor 李文利
Owner QINGDAO MUNICIPAL HOSPITAL
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