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A kind of braided wire for medical use and its preparation method and product

A braided wire and medical technology, applied in the field of medical materials, can solve the problems of braided wire movement, sling or patch erosion, and insufficient softness, and achieve the effects of reducing sliding and friction, avoiding erosion and exposure, and improving bonding

Active Publication Date: 2017-09-12
MEDPRINSHENZHEN REGENERATIVEA MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The occurrence of this situation is mainly caused by its own technical characteristics: most of the existing woven slings or patches are woven with monofilament polypropylene thread, and polypropylene thread is relatively hard, which will constantly rub against the implanted site. It may lead to puncture of local tissues; after the sling or patch is implanted in the body, the sling or patch will be displaced as the patient moves, and the braided wire and its nodes will also move, resulting in poor tissue growth and healing, or even Puncture occurs
In the prior art, attempts have been made to replace polypropylene threads with other materials such as electrospun materials. However, electrospun materials have poor mechanical strength and are not soft enough, so they can only be used clinically in areas with low requirements for mechanical strength and comfort. such as skin
Currently, there is no product that does a good job of addressing the erosion and exposure of existing slings or patches

Method used

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  • A kind of braided wire for medical use and its preparation method and product
  • A kind of braided wire for medical use and its preparation method and product
  • A kind of braided wire for medical use and its preparation method and product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0057] Prepare the braided wire for medical use as follows:

[0058] S1. Preparation of electrospinning solution: Polylactic acid was dissolved in hexafluoroisopropanol with a mass volume concentration of 5%.

[0059] S2. Perform electrospinning. The electrospinning conditions are as follows: the electrospinning voltage is 25 kV, the propulsion speed is 0.5 mL / h, and the distance from the electrospinning head to the grounded metal plate is 30 cm. After the start of electrospinning, at a distance of about 10cm from the filament outlet, a bundle of polypropylene threads continues to pass in parallel, and the polypropylene threads are continuously conveyed from one end to the other; at the same time, the polypropylene thread keeps rotating by itself during the conveying process. The conveying speed of the polypropylene wire was 3 m / min, and the rotation speed of the polypropylene wire was 100 rpm. Electrospinning will be evenly wound onto the surface of the polypropylene thread ...

Embodiment 2

[0062] Prepare the braided wire for medical use as follows:

[0063] S1. Preparation of electrospinning solution: Polylactic acid was dissolved in hexafluoroisopropanol to make the mass volume concentration of polylactic acid 15%.

[0064] S2. Perform electrospinning. The electrospinning conditions are as follows: the electrospinning voltage is 25 kV, the propulsion speed is 5 mL / h, and the distance from the electrospinning head to the grounded metal plate is 30 cm. After the start of electrospinning, at a distance of about 20 cm from the filament outlet, a bundle of polypropylene threads continued to pass in parallel, and the polypropylene thread was continuously conveyed from one end to the other; at the same time, the polypropylene thread kept rotating itself during the conveying process. The conveying speed of the polypropylene wire was 12 m / min, and the rotation speed of the polypropylene wire was 1000 rpm. Electrospinning will be evenly wound onto the surface of the pol...

Embodiment 3

[0068] Prepare the braided wire for medical use as follows:

[0069] S1. Preparation of electrospinning solution: Polylactic acid was dissolved in hexafluoroisopropanol to make the mass volume concentration of polylactic acid 7%.

[0070] S2. Perform electrospinning. The electrospinning conditions are as follows: the electrospinning voltage is 15 kV, the propulsion speed is 3 mL / h, and the distance from the electrospinning head to the grounded metal plate is 20 cm. After the start of electrospinning, at a distance of about 15 cm from the filament outlet, a bundle of polypropylene threads continued to pass in parallel, and the polypropylene thread was continuously conveyed from one end to the other; at the same time, the polypropylene thread kept rotating itself during the conveying process. The conveying speed of the polypropylene wire was 6 m / min, and the rotation speed of the polypropylene wire was 500 rpm. Electrospinning will be evenly wound onto the surface of the polypr...

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Abstract

The invention discloses a braided wire for medical use and a preparation method thereof. The braided wire for medical use includes a core layer made of synthetic high molecular polymer wire and a shell layer made of electrospinning. After the implanted medical device prepared from the braided wire is used for treating female pelvic floor dysfunction diseases, since the shell is relatively soft, the friction of the implanted medical device on the tissue can be reduced, and the shell can also stimulate tissue growth , so that the tissue and the wire of the implanted medical device form a staggered wrap, improve the combination of the implanted medical device and the tissue, and further reduce the sliding and friction between the two, so that the erosion and exposure of the existing implanted medical device can be avoided In addition, drug loading on the shell can further reduce the foreign body reaction of implanted medical devices or reduce postoperative bleeding.

Description

technical field [0001] The invention belongs to the field of medical materials, and in particular relates to a braided wire for medical use and a preparation method thereof. Background technique [0002] Braided slings or meshes have been widely used in the treatment of female pelvic floor dysfunction in the past 10 years, but in the past two years, there have been some problems with such products, such as erosion and exposure, which have brought huge secondary damage to patients , indicating that there are deficiencies in the existing device design. The occurrence of this situation is mainly caused by its own technical characteristics: most of the existing woven slings or patches are woven with monofilament polypropylene thread, and polypropylene thread is relatively hard, which will constantly rub against the implanted site. It may lead to puncture of local tissues; after the sling or patch is implanted in the body, the sling or patch will be displaced as the patient move...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): D02G3/44A61F2/08A61B17/00D06M13/144D06M10/00D06M15/03D06M101/32D06M101/20
Inventor 赖奎霖徐弢袁玉宇
Owner MEDPRINSHENZHEN REGENERATIVEA MEDICAL TECH CO LTD
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