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Monascus garlic powder health care product with lipid lowering function and application thereof

A technology of red yeast rice and garlic powder, which is applied in the direction of medical preparations containing active ingredients, application, food preparation, etc., can solve the problem of large dosage, achieve the effects of taking non-toxic, avoiding stomach damage, and preventing arteriosclerosis

Inactive Publication Date: 2014-04-09
BEIJING TIAN AN KANG JIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the late 1970s, it was found that oral administration of raw garlic to healthy and ischemic patients for 2 to 3 months could significantly reduce blood cholesterol (TC) and triglyceride (TG) levels, but this result must be obtained Larger dose required
[0011] However, there is no report on the composition containing red yeast rice, EGCG, selenium, and garlic powder simultaneously

Method used

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  • Monascus garlic powder health care product with lipid lowering function and application thereof
  • Monascus garlic powder health care product with lipid lowering function and application thereof
  • Monascus garlic powder health care product with lipid lowering function and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1 Preparation Example

[0034] 200g of red yeast rice, 126.25g of garlic powder, 120g of green tea extract (of which the EGCG content is greater than 70%), 3.75g of selenium-enriched yeast (2g / kg), filled with enteric-coated capsules after mixing, and made into 1000 capsules according to the conventional method. Each grain weighs ≥0.45g.

[0035] Dosage: Take orally, 2 times a day, 2 capsules each time.

Embodiment 2

[0036] Example 2 Research on the Synergistic Lipid-lowering Effect Between Allicin and Other Components in the Monascus Garlic Powder Composition of the Present Invention

[0037] This example studies the effect of allicin and other ingredients in the red yeast garlic powder composition on the effect of reducing various blood lipid components in serum.

[0038] 2.1 Sample

[0039] Test sample: the red yeast garlic powder composition prepared in embodiment 1, the dosage is 0.15g / kgBW every day;

[0040] Control sample: a composition without garlic powder, wherein the contents of red yeast rice and green tea extract are the same as those of the red yeast rice garlic powder composition in Example 1, and the dosage is 0.15 g / kgBW per day.

[0041] 2.2 Method

[0042] In this embodiment, a total of 36 healthy SPF grade male SD rats were used and randomly divided into three groups: blank control group, test group and control sample group. Adopt preventive hyperlipidemia animal mo...

Embodiment 3

[0061] Embodiment 3 Determination of allicin content in the red yeast rice garlic powder composition of the present invention

[0062] This embodiment studies the allicin content in the red yeast rice garlic powder composition, after measuring, the experimental results are as follows:

[0063] Table 4 Determination of garlic powder active ingredient content in the red yeast rice garlic powder composition of the present invention

[0064] project Specification content (%) Result content (%) Detection method active ingredient Allicin ≥ 1 1.17 HPLC

[0065] The test results show that the active ingredient content of garlic powder in the red yeast garlic powder composition of the present invention is 1.17%, which is greater than 1%, which is far higher than the allicin content in the commercially available garlic extract, so that the red yeast garlic powder of the present invention The composition has the function of significantly lowering blood fat. ...

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PUM

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Abstract

The invention provides a monascus garlic powder health care product with a lipid lowering function, the composition includes monascus, green tea extracts and garlic powder, the monascus content is 44% to 45% of the total weight, the green tea extract content is 26% to 27% of the total weight, the garlic powder content is 28% to 29% of the total weight, the composition has auxiliary lipid-lowering and auxiliary antitumor functions, and is especially suitable for persons in sub-health status to back to health status, and experiments prove that the composition is safe, effective, and free of toxic and side effects for long-term use.

Description

technical field [0001] The invention relates to a health product with lipid-lowering function and its application, belonging to the technical field of health food. Background technique [0002] Red yeast rice was first discovered in China in the Han Dynasty. It is a traditional food and Chinese medicinal material with a production and application history of more than one thousand years. Red yeast rice, called Danqu in ancient times, is prepared by inoculating Monascus fungi on rice and fermenting. Tao Gu, a person of the Five Dynasties, recorded "red yeast boiled meat" in "Qing Yi Lu". A variety of traditional Chinese medicine books in the past dynasties, such as "Compendium of Materia Medica", "Congxin Materia Medica", "Supplement to Materia Medica Yanyi", "Compendium of Materia Medica", "Materia Medica Preparation" and "Dictionary of Chinese Medicine" have records on red yeast rice. In particular, Li Shizhen of the Ming Dynasty recorded the most complete record of red ko...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A23L1/29A61P3/06A61P35/00A23L33/00
Inventor 葛文津张雁韩英刘惠敏
Owner BEIJING TIAN AN KANG JIAN BIOTECH
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