A pure traditional Chinese medicine preparation for oral ulcers
A technology for oral ulcer and pure traditional Chinese medicine, applied in the field of preparation of the traditional Chinese medicine preparation, can solve the problems of heavy economic and mental burden of patients, no special effect of oral ulcer, interference of diet and work and rest, and achieves no toxic and side effects, significant and reliable curative effect, Less-recurring effect
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Embodiment 1
[0026] A traditional Chinese medicine preparation for oral ulcer, which is prepared from the following raw materials in parts by weight,
[0027] 15 parts of Atractylodes macrocephala, 15 parts of dried ginger, 15 parts of Uncaria, 12 parts of Curcuma, 12 parts of Banzhilian,
[0028] 12 parts of Cortex Phellodendri, 10 parts of Gardenia, 10 parts of Licorice, 10 parts of Astragalus, 10 parts of Ophiopogon japonicus,
[0029] 7 parts of ebony plum, 7 parts of Prunella vulgaris, 5 parts of Albizia Julibrissin skin, 5 parts of melon seeds, and 3 parts of mulberry leaves.
[0030] Chinese medicine preparation preparation method of the present invention is:
[0031] (1) Take the bulk drug (proportioning unit: gram) of the above-mentioned parts by weight, and set aside;
[0032] (2) Take the Atractylodes, Gou Teng, Curcuma, Banzhi Lotus, Licorice, Plagractic, and Huan Huan Skin evenly. After soaking 5 times the weight of water for 30 minutes, boil the Wuhuo, then fry the fire for...
Embodiment 2
[0036] zoology experiment
[0037] The acute toxicity test using mice showed that compared with the control group, there was no significant difference in the mice after administration. The experiment was observed for two consecutive weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.
[0038] long-term toxicity test
[0039] Select 60 SD rats, half male and half male. Divide into 2 groups at random according to body weight, i.e. control group (distilled water of equal weight), Chinese medicine group of the present invention. There are 30 rats in each group, half male and half male. Each group of animals was intragastrically administered once a day, and after 1 month of continuous administration, 15 animals of the control group and the Chinese medicine grou...
Embodiment 3
[0041] clinical information:
[0042]Materials and methods: In order to further investigate the clinical curative effect and safety of the traditional Chinese medicine preparation of the present invention, we selected 93 patients with oral ulcers to clinically observe the curative effect of the medicine of the present invention. All cases were diagnosed according to the criteria in the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine". The patients were all from the outpatient clinic, and were randomly divided into a treatment group of 46 cases and a control group of 47 cases by double-blind method, including 45 males and 48 females, aged 7 to 62 years, of which 80% were over 30 years old.
[0043] Inclusion criteria of traditional Chinese medicine: heart-spleen accumulation heat type: clinical manifestations are erosion or ulcers of the mouth and tongue, the lesions are mostly red, and can occur on the lips, buccal gums, palate and other ...
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