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A pure traditional Chinese medicine preparation for oral ulcers

A technology for oral ulcer and pure traditional Chinese medicine, applied in the field of preparation of the traditional Chinese medicine preparation, can solve the problems of heavy economic and mental burden of patients, no special effect of oral ulcer, interference of diet and work and rest, and achieves no toxic and side effects, significant and reliable curative effect, Less-recurring effect

Active Publication Date: 2015-11-11
梅州市和谐生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although oral ulcer is a "minor problem", it brings great pain and troubles to the patient and his family. After suffering from oral ulcer, the patient's normal diet and work and rest are disturbed, and the pain causes insomnia, irritability and tension. , depression, loss of interest in work and life, etc., especially recurrent oral ulcers, the financial and mental burden on patients is even heavier
[0003] In terms of Western medicine, there is no specific therapy for the treatment of oral ulcers. At present, the principle of treating recurrent oral ulcers is to eliminate the pathogenic factors, relieve symptoms, promote healing, and reduce recurrence.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A traditional Chinese medicine preparation for oral ulcer, which is prepared from the following raw materials in parts by weight,

[0027] 15 parts of Atractylodes macrocephala, 15 parts of dried ginger, 15 parts of Uncaria, 12 parts of Curcuma, 12 parts of Banzhilian,

[0028] 12 parts of Cortex Phellodendri, 10 parts of Gardenia, 10 parts of Licorice, 10 parts of Astragalus, 10 parts of Ophiopogon japonicus,

[0029] 7 parts of ebony plum, 7 parts of Prunella vulgaris, 5 parts of Albizia Julibrissin skin, 5 parts of melon seeds, and 3 parts of mulberry leaves.

[0030] Chinese medicine preparation preparation method of the present invention is:

[0031] (1) Take the bulk drug (proportioning unit: gram) of the above-mentioned parts by weight, and set aside;

[0032] (2) Take the Atractylodes, Gou Teng, Curcuma, Banzhi Lotus, Licorice, Plagractic, and Huan Huan Skin evenly. After soaking 5 times the weight of water for 30 minutes, boil the Wuhuo, then fry the fire for...

Embodiment 2

[0036] zoology experiment

[0037] The acute toxicity test using mice showed that compared with the control group, there was no significant difference in the mice after administration. The experiment was observed for two consecutive weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.

[0038] long-term toxicity test

[0039] Select 60 SD rats, half male and half male. Divide into 2 groups at random according to body weight, i.e. control group (distilled water of equal weight), Chinese medicine group of the present invention. There are 30 rats in each group, half male and half male. Each group of animals was intragastrically administered once a day, and after 1 month of continuous administration, 15 animals of the control group and the Chinese medicine grou...

Embodiment 3

[0041] clinical information:

[0042]Materials and methods: In order to further investigate the clinical curative effect and safety of the traditional Chinese medicine preparation of the present invention, we selected 93 patients with oral ulcers to clinically observe the curative effect of the medicine of the present invention. All cases were diagnosed according to the criteria in the "Guiding Principles for Clinical Research of New Drugs of Traditional Chinese Medicine". The patients were all from the outpatient clinic, and were randomly divided into a treatment group of 46 cases and a control group of 47 cases by double-blind method, including 45 males and 48 females, aged 7 to 62 years, of which 80% were over 30 years old.

[0043] Inclusion criteria of traditional Chinese medicine: heart-spleen accumulation heat type: clinical manifestations are erosion or ulcers of the mouth and tongue, the lesions are mostly red, and can occur on the lips, buccal gums, palate and other ...

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PUM

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Abstract

The invention relates to a pure traditional Chinese medicine preparation for dental ulcers. The pure traditional Chinese medicine preparation is prepared from the following raw materials: 15 parts of white atractylodes rhizome, 15 parts of rhizoma zingiberis, 15 parts of uncaria rhynchophylla, 12 parts of curcuma zedoary, 12 parts of portulaca grandiflora, 12 parts of golden cypress, 10 parts of fructus gardeniae, 10 parts of licorice root, 10 parts of astragalus membranaceus, 10 parts of radix ophiopogonis, 7 parts of smoked plum, 7 parts of spica prunellae, 5 parts of cortex albiziae, 5 parts of muskmelon seeds and 3 parts of folium mori. When the pure traditional Chinese medicine preparation is used for treating the dental ulcers, the treatment course is short; the total effective rate is high; and the dental ulcers are difficult to relapse after being cured. In addition, the pure traditional Chinese medicine preparation is simple in process, so that the production cost is lowered; and the economical burden of a patient is lightened.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pure traditional Chinese medicine preparation for oral ulcer, and also relates to a preparation method of the traditional Chinese medicine preparation. Background technique [0002] Oral ulcers, also known as "oral sores", are superficial ulcers that occur on the oral mucosa. The size can range from rice grains to soybeans, and they are round or oval. The pain caused by irritating food usually heals by itself in one to two weeks. Oral ulcers reoccur periodically, several times a year, several times a month, and even old and new lesions appear alternately. Oral ulcers are characterized by recurring periodic attacks, which can occur in any part of the oral mucosa, and are more common in the oral cavity's lips, cheeks, soft palate, or gums, where single or multiple elliptical or circular ulcers of different sizes occur , the surface is covered wi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P1/02
Inventor 蔡圳管爱忠
Owner 梅州市和谐生物科技有限公司
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