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Traditional Chinese medicine for treating heat-toxicity accumulation type chronic osteomyelitis and preparation method thereof

A technology of chronic osteomyelitis and accumulation type, which is applied in the field of traditional Chinese medicine and its preparation for the treatment of heat-toxin accumulation type chronic osteomyelitis, can solve the problems of curative effect decline, easy recurrence, drug resistance variation, etc., and achieve exact curative effect and toxicity. Effect with few side effects

Inactive Publication Date: 2014-01-22
秦峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the irrational use of antibiotics, pathogenic bacteria often have drug resistance and mutation, which reduces the curative effect
Although surgical treatment can remove the lesion, it has the disadvantage of easy recurrence

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0059] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine, wherein the dosage form of the traditional Chinese medicine for oral administration is a tablet, and the preparation method comprises the following steps:

[0060] Step 1: Mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 80-90% 3-5 times the mass of the mixture, heat and reflux for 1-2 hours, extract, and filter to obtain the first extract , add ethanol with an alcohol concentration of 80-90% relative to the mass of the medicinal residues that is 1 to 3 times the mass of the medicinal residues obtained by filtering, heat and reflux for 35 to 45 minutes, extract, and filter to obtain a second extract, mix the first extract with The second extracts were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0061] The second step: put the dry...

Embodiment 1

[0078] Embodiment 1: tablet (medicine for oral administration)

[0079] Take 250g of oxtail, 240g of kudiding, 290g of rag grass, 160g of plough grass, 280g of ground beetle, 50g of houttuynia cordata, 70g of lantana flower, 60g of star anise lotus, 150g of mountain branch root, 50g of big leaf vine, keel Wind 130g and swollen joint wind 260g;

[0080] Prepare as follows:

[0081] The first step: mix the various raw materials of the traditional Chinese medicine, add ethanol with an alcohol concentration of 90% that is 5 times the mass of the mixture, heat and reflux for 2 hours, extract, filter to obtain the first extract, and add the dregs obtained by filtering Ethanol with an alcohol concentration of 90% relative to the mass of the dregs is heated to reflux for 45 minutes, extracted, filtered to obtain the second extract, the first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried , to obtain dry paste...

Embodiment 2

[0084] Embodiment 2: Capsules (medicine for oral administration)

[0085] Take 280g of oxtail, 220g of kudiding, 260g of rag grass, 170g of plough grass, 260g of ground beetle, 60g of houttuynia cordata, 70g of lantana flower, 60g of star anise lotus, 170g of mountain branch root, 70g of large leaf vine, keel Feng 110g and swollen joint wind 270g;

[0086] Prepare as follows:

[0087] The first step is to mix the raw materials of the traditional Chinese medicine, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 60 minutes, extract, and filter to obtain the first extract; filter the obtained dregs and then add Ethanol with an alcohol concentration of 90% that is 3 times the mass of the dregs is heated to reflux for 30 minutes, extracted, and filtered to obtain the second extract; the first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried , to o...

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Abstract

The invention provides a traditional Chinese medicine for treating heat-toxicity accumulation type chronic osteomyelitis and a preparation method thereof. The traditional Chinese medicine is prepared from orally-taking medicines and external medicines, wherein the orally-taking medicines comprise the following various bulk drugs: riparian greenbrier root and rhizome, bunge corydalis herb, kweiyang betony herb, japanese violet herb, bees, cordate houttuynia, rhododendron delavayi, sixangular dysosma rhizome, glabrousleaf pittosporum root, tonkin tinomiscium stem, caulis alsophilae, glabrous sarcandra herb; the external medicines comprise the following various bulk drugs: umbrellaleaf, adiantum capillus-veneris, garden balsam stem, purslane speedwell herb, laciniate kalanchoe herb, henbit, four-leaf clover, kamuning, Chinese fevervine herb and common rockvine herb. According to the traditional Chinese medicine, an internal use mode and an external use mode are combined, the traditional Chinese medicine has the functions of clearing away heat and toxic materials, promoting blood circulation and removing meridian obstruction, removing rotten scattered stasis and relieving swelling and pain, and has the exact curative effect in treatment of the heat-toxicity accumulation type chronic osteomyelitis and small side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating heat-toxin-accumulated chronic osteomyelitis and a preparation method thereof. Background technique [0002] Most chronic osteomyelitis develops as a result of inadequate or untimely treatment of acute osteomyelitis. However, if the pathogenic bacteria of acute osteomyelitis have low virulence or the patient's resistance is strong, it may be subacute or chronic osteomyelitis from the beginning, and osteomyelitis infected by skin wounds is often chronic osteomyelitis from the beginning . The pathogenic bacteria of chronic osteomyelitis is mainly Staphylococcus aureus pyogenes. Those with chronic sinuses often have a mixed infection of various bacteria. The disease is prone to occur in the metaphysis of long tubular bones in children. Most of them have a history of acute osteomyeli...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/87A61P19/00A61P31/04
Inventor 赵永东杨美艳秦峰
Owner 秦峰
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