Method for preparing artificial bone by secondary sintering using selective laser and temperature-controlled furnace

Abstract

The invention discloses a molding method for realizing secondary sintering preparation of a high-toughness three-dimensional nano ceramic artificial bone by utilizing a selective laser and a temperature control furnace. In the first sintering, the selective laser is utilized for layer-by-layer scanning of a biological ceramic powder according to artificial bone model information, and layers are superposed to obtain a nano artificial bone initial green body having a complex geometric profile and controllable interconnected micropores; and in the second sintering, the laser molded piece is subjected to long-time heat preservation at a relatively low sintering temperature in the temperature control furnace, grain boundary migration is inhibited in the heat preservation stage, grain boundary diffusion is maintained, thus grain growth is under control, and a densification process can be still carried out until the artificial bone is fully densified. The molded artificial bone not only has the profile consistent with an implantation site and has the interconnected and controllable pore space structure, but also is a nano biological ceramic artificial bone scaffold having good mechanical properties.

Description

technical field [0001] The invention belongs to the field of advanced and rapid manufacturing of nano-biological materials, and specifically relates to a method of using nano-biological ceramic powder as a raw material to obtain an initial green body with a complex geometric shape and penetrating interconnected micropores by selective laser sintering to complete the first sintering. A temperature-controlled furnace makes it densified at low temperature to realize the second sintering to prepare a high-toughness nano bioceramic artificial bone. Background technique [0002] Bone is the most important hard tissue in the human body. It plays an irreplaceable role in protecting internal organs, providing attachment for muscles, and producing blood cells. With the development of my country's industry, transportation, sports and other undertakings and the aging of the population, fractures and bone defects caused by trauma and disease have increasingly become a major problem threa...

AI Technical Summary

Problems solved by technology

[0006] Therefore, in order to solve the above technical problems, and aiming at the problem that the ceramic artificial bone materials in tissue engineering cannot take into account the three-dimensional geometric structure and mechanical properties of the artificial bone, a rapid prototyping method was invented to prepare the macroscopic structure and the defect tissue almost completely. 3D nano-bioceramic artificial bone with completely penetrated internal pores and significantly improved mechanical properties, especially toughness, is of great significance