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Breast implant support device based on periplast material and preparation method thereof

一种乳房假体、支撑装置的技术，应用在假体、假乳房、组织再生等方向，能够解决易出现差错、提高手术费用、整形美容效果不易掌控等问题，达到避免下垂和移位、缩短手术时间、好整形美容效果的效果

Active Publication Date: 2013-11-20
BEIJING RUIJIAN GAOKE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because these tissue materials are usually planar membrane materials, during breast reconstruction, doctors have to cut and shape them on the spot according to the size of the required area during the operation. The specifications are different and the shape is irregular, and they often cannot be well matched with the selected breast tissue. The prosthesis and the patient's surgical area match, and the cosmetic effect is not easy to control
For example, it is difficult to avoid folding and contraction, it is difficult to control the shape of the breast, and it is difficult to achieve the straight posture of the reconstructed breast
At the same time, because this kind of material is very expensive, it is cut and formed at the operation site, and doctors rely on visual inspection to cut it, which is prone to errors, which not only wastes materials, but also increases the cost of surgery

Method used

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  • Breast implant support device based on periplast material and preparation method thereof
  • Breast implant support device based on periplast material and preparation method thereof
  • Breast implant support device based on periplast material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Example 1: Fresh pericardium was collected from freshly slaughtered cattle. After manually removing the adhering adipose tissue, it was temporarily stored in a 0.9% sodium chloride solution and placed in a refrigerator at 4 degrees Celsius overnight. After washing with ultrasonic water bath for 30 minutes, the thickness of pericardium was measured to be 0.4-0.7 mm. Decellularize with 1 liter of 2% sodium deoxycholate solution (dissolved in hydroxyethylpiperazine ethanethiosulfonic acid buffer solution, containing 10 mM EDTA, pH 7.4) per 100 g of pericardial material, on a shaker Shake for 16 hours. The decellularized pericardium was treated with 1N sodium hydroxide solution for one hour. Adjust the pH to neutral with 10N hydrochloric acid. Treat with sterile 12% sodium chloride solution for 6 hours and rinse with sterile 0.9% sodium chloride solution 4 times for 8 hours each. The treated pericardium increased in thickness. Decellularized pericardium was temporarily...

Embodiment 2

[0060] Example 2: Decellularized bovine pericardium was used with a thickness of 0.6-0.9 mm, a length of 20 cm and a width of 16 cm. cropped as Figure 3a Two different sizes and shapes of petals are shown, two of which are 9 cm wide and 7 cm high, and the other two are 7 cm wide and 9 cm high. 16 holes with a diameter of 3 mm were drilled in the area where the four petals were connected, and the hole spacing was 1 cm. The flanges connected between the flaps are sutured together with polypropylene sutures to form a biological tissue flat bowl cover or cup cover with a diameter of about 9 cm and a height of about 7 cm ( Figure 3b ). After suturing, wash with 0.9% sodium chloride solution; sterilize with 25kGy gamma radiation after encapsulation. The device can support 250cc to 450cc breast prosthesis, covering about 180 square centimeters of the surface of the breast prosthesis.

Embodiment 3

[0061] Example 3: Fresh pig skins were collected from freshly slaughtered pigs, and after manual plucking, they were layered into dermis with a thickness of about 0.8 mm, and frozen at -20 degrees Celsius. After the dermis was thawed, it was soaked in saline solution containing 100 mg of gentamicin per liter for 4 hours. The porcine dermis was transferred into 0.5% polyethylene glycol octyl phenyl ether solution for washing for 20 hours. After decellularization and washing, rinse twice with normal saline for 120 minutes each time. After cleaning, sterilization and virus inactivation were carried out with 0.2% peracetic acid for 4 hours. Finally, rinse with sterile normal saline until there is no residue of polyethylene glycol octyl phenyl ether and enzyme. The thickness of the treated dermis was increased by about 20%. The treated dermal matrix was temporarily stored in 0.9% sodium chloride solution.

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Abstract

The invention relates to a biological tissue acellular periplast material used for a breast implant support device. The support device is formed by cutting a membrane material into a petaling planar biological periplast blank, and splicing the adjacent edges. The support device can be matched with the breast implant and can provide supporting, fixing and covering for the breast implant in various surgeries including breast shaping and orthopedy, prevent the breast implant from decline and displacement, and obtain excellent shaping and cosmetic results. After being implanted, the periplast material can be integrated with surrounding breast tissue and transform into human body new tissue, and no foreign body remains. The invention further relates to a method for preparing the support device, and a membrane biological periplast material.

Description

technical field [0001] The present invention relates to the field of plastic surgery, in particular to an implantable biological device and a preparation method for breast prosthesis fixation, support and covering in various surgical operations of female breast augmentation, breast reconstruction and breast plastic surgery. Background technique [0002] Female breast augmentation, breast reconstruction and breast plastic orthopedic surgery are widely used in breast cancer patients who have undergone resection and those who need plastic surgery. Over the past 20 years, such surgical techniques have been greatly improved. The chance of complications has been greatly reduced, and breast implants have been widely used in breast augmentation and breast reconstruction surgery. However, using breast implants for breast augmentation, breast reconstruction and breast plastic surgery will still cause many serious problems for a long period of time after the operation. These problems ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/12A61L27/36
CPCA61F2/12A61F2230/0095A61F2240/001A61L27/3641A61L2430/04
Inventor 刘志刚刘新华
Owner BEIJING RUIJIAN GAOKE BIOTECH
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