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Medicine for curing non-alcoholic steatohepatitis and preparation method thereof

A steatohepatitis, non-alcoholic technology, applied in the preparation of the drug, in the field of drugs for the treatment of non-alcoholic steatohepatitis (NASH), can solve the problem of less than ideal curative effect, no recognized cure drugs, and no breakthrough progress has been made yet and other problems, to achieve the effect of saving Chinese herbal medicine resources, making economical production, and enriching medicine sources.

Inactive Publication Date: 2013-10-02
邵阳县中医医院
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Literature reports: There are many researches on the treatment of non-alcoholic steatohepatitis, most of which focus on clearing away heat and dampness. Not ideal, breakthrough progress has not been made, so far there is no recognized cure drug at home and abroad

Method used

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  • Medicine for curing non-alcoholic steatohepatitis and preparation method thereof
  • Medicine for curing non-alcoholic steatohepatitis and preparation method thereof
  • Medicine for curing non-alcoholic steatohepatitis and preparation method thereof

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Embodiment Construction

[0013] The medicine for treating non-alcoholic steatohepatitis is composed of the following traditional Chinese medicine raw materials in the weight ratio: 3.5-10 parts of astragalus, 3-10 parts of coix seed, 3.5-10 parts of Alisma, 2-6 parts of seaweed, 4-10 parts of dandelion 3.5-10 parts of Danshen, 3-8 parts of Polygonum cuspidatum, 5-15 parts of Hawthorn, 2-6 parts of Bupleurum, 3.5-10 parts of lotus leaf, 2-6 parts of Polygonum multiflorum.

[0014] The preferred formula is: 6 parts of astragalus, 5 parts of coix seed, 4 parts of Alisma, 6 parts of seaweed, 4 parts of dandelion, 10 parts of salvia, 6 parts of knotweed, 12 parts of hawthorn, 6 parts of Bupleurum, 10 parts of lotus leaf, and 6 parts of Polygonum multiflorum .

[0015] The dosage form of the medicine is honeydew pill. It was named "Qushi Huayu Xiaozhi Pill". It can also be made into other pharmaceutical dosage forms.

[0016] Preparation method 1: Weigh the raw materials according to the stated ratio, 3....

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Abstract

The invention provides medicine for curing non-alcoholic steatohepatitis and a preparation method thereof. The medicine is prepared from traditional Chinese medicine as raw materials, and the ingredients of the raw materials are mainly radix astragali, semen coicis, rhizoma alismatis, seaweed, dandelion, radix salviae miltiorrhizae, polygonum cuspidatum, hawthorn, radix bupleuri, folium nelumbinis and polygonum multiflorum. The medicine is prepared into a water-honeyed pill, namely a dampness-dispelling stasis-dispersing fat-fighting pill. The traditional Chinese medicine is selected according to three-method combination of clearing heat and dampness, activating blood and dissolving stasis, and soothing liver and strengthening spleen, and a prescription is formed according to a principle of dispelling dampness, removing stasis and strengthening spleen, so that the effects of removing fat, dropping enzyme and repairing damaged liver cells can be achieved. Animal acute toxicity tests and pharmacodynamic tests prove that the medicine has good safety, can obviously control blood fat and improve the fatty liver, and has an obvious effect of losing weight. The medicine is clinically applied, the basic cure rate is 57.5 percent, the total effective rate is 94.3 percent, and the curative effect is higher than that of national medicine 'simvastatin' approved by the state and the current medicine for curing the fatty liver in China.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medicine for treating non-alcoholic steatohepatitis (NASH); the invention also relates to a preparation method of the medicine. Background technique [0002] In recent years, due to changes in the diet structure and lifestyle of the masses, the incidence of non-alcoholic fatty liver disease (NAFLD) has continued to rise, and has gradually replaced hepatitis B virus as the main cause of chronic liver disease in my country. The prevention and treatment of NAFLD is not only a medical problem, but also a social problem. Therefore, it is imperative to actively do a good job in the prevention and treatment of NAFLD. [0003] Non-alcoholic fatty liver disease (NAFLD) is a metabolic stress-induced liver injury closely related to insulin resistance (IR) and genetic susceptibility. The disease spectrum includes non-alcoholic simple fatty liver (NAFL), non-alcoholic steatohep...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P1/16
Inventor 阳义成王武军
Owner 邵阳县中医医院
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