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Application of Hypericum longiflorum extract in the preparation of anti-tumor and tumor-inhibiting drugs

A technology of St. John's Wort and anti-tumor drugs, which is applied in the field of traditional Chinese medicine, can solve problems such as the anti-tumor effect of St. John's Wort, and achieve the effect of inhibiting tumor growth.

Inactive Publication Date: 2016-04-27
TIANJIN UNIV OF SCI & TECH
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  • Description
  • Claims
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Problems solved by technology

There is no report on the anti-tumor effect of Hypericum changzhu

Method used

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  • Application of Hypericum longiflorum extract in the preparation of anti-tumor and tumor-inhibiting drugs
  • Application of Hypericum longiflorum extract in the preparation of anti-tumor and tumor-inhibiting drugs
  • Application of Hypericum longiflorum extract in the preparation of anti-tumor and tumor-inhibiting drugs

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Embodiment Construction

[0021] The present invention will be further described in detail below through the specific examples, the following examples are only descriptive, not restrictive, and cannot limit the protection scope of the present invention with this.

[0022] Unless otherwise specified, the reagents used in the present invention are conventional reagents; unless otherwise specified, the methods used are conventional methods.

[0023] The application of Hypericum lanceolata extract provided by the present invention in anti-tumor and inhibiting tumor proliferation, wherein the extract of Hypericum lanceolata is extracted from the whole plant of Hypericum lanceolata, and the extraction is carried out according to the following steps of:

[0024] The preparation method of described Hypericum longifolia extract is as follows:

[0025] ⑴The whole Hypericum lanceolata herb is dried in the shade, crushed into coarse powder, passed through a 60-mesh analytical sieve, and ultrasonically extracted (...

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Abstract

The invention relates to an application of a hypericum ascyron extract in preparation of antitumor and tumor growth suppressing medicines. According to the invention, the hypericum ascyron extract has remarkable inhibiting effect on proliferation of tumor cells through analysis of cytotoxicity, cell viability and apoptosis by the hypericum ascyron extract. The hypericum ascyron extract has proliferation inhibiting effect and apoptotic effect to human cervical carcinoma cell (Hela).

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to the extract of Hypericum lanceolata, especially the application of the extract of Hypericum lanceolata in preparing anti-tumor and inhibiting tumor growth drugs. Background technique [0002] Malignant tumors, as one of the largest public health problems in the world, have greatly endangered human health and will become the number one killer of human beings in the new century. From a global perspective, in 2000, there were 10.1 million new cancer cases, 6.2 million deaths, and 22.4 million cancer cases. 15 million new cases. At the same time, malignant tumors are no longer just a serious disease in developed industrial countries, and developing countries are facing a greater burden of disease. In 2008, developing countries accounted for 56% of the incidence of malignant tumors; in 2009, 80% of cancer patients were concentrated in low- and middle-income countries. By 20...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07B63/00A61K36/185A61P35/00
Inventor 张同存李秀梅罗学刚王楠李琨马宁张瑶白俊珍
Owner TIANJIN UNIV OF SCI & TECH
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