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Weishuning tablet Chinese medicinal composition and preparation method thereof

The technology of Weishuning tablet and composition is applied in the field of Weishuning tablet traditional Chinese medicine composition and preparation thereof, and can solve the problems of high recurrence rate of clinical patients, unacceptable taste of patients, unsatisfactory curative effect and the like.

Inactive Publication Date: 2013-07-17
褚小红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] "Weishuning Granules" under the item of WS3-B-1579-93 in the eighth volume of "Prescriptions of Traditional Chinese Medicine" issued by the Ministry of Standards is a pure Chinese medicine preparation. , chronic gastritis and other stomach diseases have a certain effect, but we also found in clinical practice that the effect is not ideal and the curative effect is unstable; and the dosage is large, the taste is difficult for patients to accept, and it is inconvenient to carry
On May 5, 2010, the Chinese Patent Gazette disclosed a patent application for a traditional Chinese medicine composition for treating stomach diseases and its preparation method and quality control method. The publication number is CN101700287A. The applicant's many years of research found that the curative effect of this process is not very satisfactory, and the recurrence rate of clinical patients is relatively high

Method used

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  • Weishuning tablet Chinese medicinal composition and preparation method thereof
  • Weishuning tablet Chinese medicinal composition and preparation method thereof
  • Weishuning tablet Chinese medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0097] prescription:

[0098] Licorice 595g, sea cuttlefish 595g, white peony 464g

[0099] Atractylodes 310g, Corydalis 310g, Codonopsis 119g;

[0100] The preparation method is: the above six flavors, add 45% ethanol and decoct twice, add 10 times the amount for the first time, add 8 times the amount for the second time, 2 hours each time, filter the decoction liquid, combine the filtrate, stand still, take The supernatant liquid is concentrated to 60°C to obtain a clear ointment with a relative density of 1.08-1.10, which is spray-dried, and an appropriate amount of dextrin is added to form granules, dried at 70°C, compressed into 1000 tablets, and coated to obtain tablets.

Embodiment 2

[0102] prescription:

[0103] Licorice 595g, sea cuttlefish 595g, white peony 464g

[0104] Atractylodes 310g, Corydalis 310g, Codonopsis 119g;

[0105] The preparation method is: the above six flavors, add 40% ethanol to decoct twice, add 10 times the amount for the first time, add 8 times the amount for the second time, 2 hours each time, filter the decoction liquid, combine the filtrate, let stand, take The supernatant liquid is concentrated to 60°C to obtain a clear ointment with a relative density of 1.08-1.10, which is spray-dried, and an appropriate amount of dextrin is added to form granules, dried at 70°C, compressed into 1000 tablets, and coated to obtain tablets.

Embodiment 3

[0107] prescription:

[0108] Licorice 595g, sea cuttlefish 595g, white peony 464g

[0109] Baizhu 310g Corydalis 310g Codonopsis 119g;

[0110] The preparation method is: the above six flavors, add 50% ethanol to decoct twice, add 10 times the amount for the first time, add 8 times the amount for the second time, 2 hours each time, filter the decoction liquid, combine the filtrates, stand still, take The supernatant liquid is concentrated to 60°C to obtain a clear ointment with a relative density of 1.08-1.10, which is spray-dried, and an appropriate amount of dextrin is added to form granules, dried at 70°C, compressed into 1000 tablets, and coated to obtain tablets.

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Abstract

The invention discloses a Weishuning tablet Chinese medicinal composition and a preparation method thereof. The composition is prepared from licorice, cuttlebone, white peony root, white atractylodes rhizome, corydalis tuber and pilose asiabell root in a certain ratio. The composition has the effects of tonifying Qi, tonifying spleen, relieving hyperacidity and relieving pain, and is applied to stomach duct pain, warm and press preference, vomiting of acid water and ulcers of stomach and duodenums due to spleen and stomach qi deficiency and liver-stomach disharmony. Compared with the prior art, the composition has the advantages that the process is advanced, the clinical pharmacodynamic experiment effect is improved remarkably compared with the conventional preparation, and the composition has high bioavailability and does not have any toxic or side effect.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition of Weishuning tablets and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine pharmacy. technical background [0002] "Weishuning Granules" under the Ministry of Standard "Prescriptions of Traditional Chinese Medicines" Volume 8 WS3-B-1579-93 is a pure Chinese medicine preparation. After years of clinical application, the medicine has been used in the treatment of gastric and duodenal ulcers. , Chronic gastritis and other gastric diseases have a certain effect, but we have also found in the clinic that the effect is not ideal and the effect is unstable; and the dosage is large, the taste is difficult to be accepted by the patient, and it is inconvenient to carry. The Chinese Patent Bulletin published a patent application for a Chinese medicinal composition for the treatment of gastric disease and its preparation method and quality control method ...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K9/28A61P1/04A61P29/00A61K35/56A61K35/618
Inventor 褚小红
Owner 褚小红
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