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Sandworm polypeptide enteric capsule

A technology of enteric-coated capsules and sandworms, applied in applications, food preparation, food science, etc., to achieve significant antioxidant activity

Active Publication Date: 2013-06-26
薛命雄
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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After searching, no technical disclosure of sandworm polypeptide enteric-coated capsules was found

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Examples

Experimental program
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Effect test

Embodiment 1

[0018] Concrete preparation steps:

[0019] (1) Cleaning of sandworms: take fresh sandworms, wash them with water, mash them to obtain sandworm slurry for later use;

[0020] (2) Enzymatic hydrolysis: Take 10000mL sandworm pulp and add 20000-60000mL distilled water to stir evenly, adjust the pH value to 7 with 1mol / L NaOH, add papain with an activity of 100,000 U / g per 1g / 100mL and 40,000 U / g of flavor protease complex enzymes were used for hydrolysis, wherein the ratio of papain to flavor protease was 1:0.5-1.5, hydrolyzed at 30-60°C for 4 hours, boiled for 10 minutes to inactivate the enzyme, and centrifuged at 3000-5000r / min for 10 minutes to obtain Enzyme solution for use;

[0021] (3) Microfiltration and dialysis: the enzymatic hydrolysis solution is microfiltered through a microfiltration membrane with a pore size of 30nm to remove suspended solids and bacteria; it is dialyzed through a 2000Da dialysis membrane to remove free amino acids and low-priced salt ions to obta...

Embodiment 2

[0027] Concrete preparation steps:

[0028] (1) Cleaning of sandworms: same as in Example 1;

[0029] (2) Enzymatic hydrolysis: take 10000mL sandworm pulp and add 20000-60000mL distilled water to stir evenly, adjust the pH value to 7.5 with 1mol / L NaOH, and add papain with an activity of 100,000 U / g per 1.5g / 100mL Hydrolyze with 40,000 U / g flavor protease compound enzyme, wherein the ratio of papain to flavor protease is 1:0.5-1.5, hydrolyze at 30-60°C for 4 hours, boil for 10 minutes to kill the enzyme, centrifuge at 3000-5000r / min for 10 minutes, Obtain the enzymatic solution for subsequent use;

[0030] (3) Microfiltration and dialysis: same as Example 1;

[0031] (4) Prepare according to the following prescription:

[0032] Peptide powder 60g Mannitol 60g Magnesium stearate 2.5g

[0033] Sodium deoxycholate 10 grams;

[0034] (5) Mix the above raw materials evenly, and put them into the enteric-coated capsule shell according to the conventional process, and the produc...

Embodiment 3

[0036] Concrete preparation steps except (4), all the other are identical with embodiment 1;

[0037] (4) Prepare according to the following prescription:

[0038] Peptide powder 50g Mannitol 50g Magnesium stearate 2g

[0039] Sodium deoxycholate 8 grams.

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Abstract

The invention discloses a sandworm polypeptide enteric capsule. A sandworm polypeptide capsule is used as an antioxidant material which is applied to eliminating human body free radicals and is absorbed in a weak basic environment in the intestinal tract, so that the absorption rate and the bioavailability are improved. The sandworm polypeptide is extracted by steps of sandworm washing, enzyme hydrolysis, microfiltration, dialysis and the like. Then, the sandworm polypeptide powder is used together with mannitol, magnesium stearate and sodium deoxycholate to prepare the enteric capsule. The sandworm polypeptide enteric capsule provided by the invention has the antioxidant function, can eliminate human body free radicals, and is high in bioavailability and extremely easy to absorb.

Description

technical field [0001] The invention relates to a sandworm polypeptide enteric-coated capsule, which belongs to the fields of biotechnology and food processing. Background technique [0002] Sandworm also known as checkered starworm Sipunculus nudus , belonging to the phylum Astrozoa and the genus Astrocystus, is a no-segmented, worm-like marine coelomate, warm-water. Live in the low tide line area, distributed in tropical and subtropical seas. Sandworms are mainly distributed in the southeast coast of China. They are one of the large-scale benthic economic animals in the mangrove area of ​​China. Their meat is crisp and tender, delicious, rich in protein, various amino acids and trace elements. Medicinal diet. Its edible and medicinal value are recorded in various herbal medicines in my country. In some areas, it is used instead of the traditional Chinese medicine Cordyceps sinensis, and it is mainly used for bone flushes, night sweats due to yin deficiency, chest tightn...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L33/00
Inventor 薛命雄
Owner 薛命雄
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